Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T79473 | Target Info | |||
| Target Name | Luteinizing hormone receptor (LHCGR) | ||||
| Synonyms |
Luteinizing hormone-releasing hormone receptor; LSH-R; LHRH receptor; LHCGR; LH/CG-R
Click to Show/Hide
|
||||
| Target Type | Successful Target | ||||
| Gene Name | LHCGR | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(S)-N-(1-Amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-4-(1-(4-tert-butylphenyl)-3-(pyridin-4-yl)-1H-pyrazol-5-ylamino)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL247504; SCHEMBL4946481; BDBM50206404
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
(S)-2-{3-[2-(4-Tert-butyl-phenyl)-5-pyridin-3-yl-2H-pyrazol-3-yl]-propionylamino}-3-(4-hydroxy-phenyl)-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL438685; SCHEMBL4944883; BDBM50206396
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2080-5. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.