Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T84117 | Target Info | |||
Target Name | 5-HT 1E receptor (HTR1E) | ||||
Synonyms |
Serotonin receptor 1E; S31; 5-hydroxytryptamine receptor 1E; 5-HT1E; 5-HT-1E; 5-HT 1E
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Target Type | Successful Target | ||||
Gene Name | HTR1E | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID |
Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
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Compound Name |
1-[2-Hydroxy-3-methyl-4-[[4-[4-(2H-tetrazol-5-yl)pyridin-2-yl]oxyphenyl]methoxy]phenyl]ethanone
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Investigative | Compound Info | ||
Synonyms |
CHEMBL3899832; SCHEMBL3163790; BDBM50207400
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Activity |
Ki > 5370000 nM
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[1] |
References | Top | ||||
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REF 1 | Discovery of dual positive allosteric modulators (PAMs) of the metabotropic glutamate 2 receptor and CysLT1 antagonists for treating migraine headache. Bioorg Med Chem Lett. 2017 Jan 15;27(2):323-328. |
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