Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T85943 | Target Info | |||
| Target Name | Proto-oncogene c-Src (SRC) | ||||
| Synonyms |
pp60c-src; Tyrosine kinase (pp60(src)); Src tyrosine kinase; SRC1; Proto-oncogene tyrosine-protein kinase Src; Pp60(src); P60-Src; C-src TK; C-Src
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| Target Type | Successful Target | ||||
| Gene Name | SRC | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 486 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Imatinib
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Approved | Compound Info | ||
| Synonyms |
Cgp 57148; Glamox; Glamox (TN); Gleevec (TN); Glivec (TN); Imatinib (INN); Imatinib (STI571); Imatinib Methansulfonate; Imatinib [INN:BAN]; 112GI019; 152459-95-5; BKJ8M8G5HI; CCRIS 9076; CGP-57148; CHEMBL941; Imatinib free base; STI; UNII-BKJ8M8G5HI
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
HIF-1alpha
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Phase 4 | Compound Info | ||
| Synonyms |
Unii-NA856793UT; 192705-79-6; PD-166866; PD166866; PD 166866; UNII-NA856793UT; CHEMBL299763; NA856793UT; 1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea; 1-(2-Amino-6-(3,5-dimethoxyphenyl)-pyrido(2,3-d)pyrimidin-7-yl)-3-tert-butyl urea; Urea,N-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-; 1-[2-Amino-6-(3,5-dimethoxyphenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butyl urea; 6-arylpyrido[2,3-d]pyrimidine deriv 25; AC1NS3U5; SCHEMBL1248489; BDBM3443; CTK4E1060
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
ABT-869
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Phase 3 | Compound Info | ||
| Synonyms |
Linifanib; ABT 869; S1003_Selleck; AL-39324; RG-3635; ABT869, Linifanib, AL-39324, RG3635; N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea; N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
Enzastaurin
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Phase 3 | Compound Info | ||
| Synonyms |
LY317615; LE-0014; LY317615, Enzastaurin; 3-(1-methyl-1H-indol-3-yl)-4-{1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione; 3-(1-methylindol-3-yl)-4-[1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]indol-3-yl]pyrrole-2,5-dione
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| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
Genistein
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Phase 2/3 | Compound Info | ||
| Synonyms |
Bonistein; GEN; Genestein; Genisteol; Genisterin; Prunetol; Sophoricol; Differenol A; G 6649; G10000; IN1327; NPI 031L; STO514; TNP00151; GENISTEIN (ENDOCRINE DISRUPTER); Lactoferrin-genistein; PTI G4660 (Genistein); PTI-G4660; SIPI 807-1; C.I. 75610; SIPI-9764-I; ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)); 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; ,5,7-Trihydroxyisoflavone; 4',5, 7-Trihydroxyisoflavone; 4',5,7-Trihydroxy isoflavone; 4',5,7-Trihydroxyisoflavone; 4,5,7-Trihydroxyiso-flavone; 4,6,7-Trihydroxyisoflavone; 5,7,4'-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
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| Activity |
IC50 = 75000 nM
|
[5] | |||
| Compound Name |
LY333531
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Phase 2 | Compound Info | ||
| Synonyms |
Ruboxistaurin; 169939-94-0; LY-333531; Ruboxistaurin [INN]; LY 333531; UNII-721809WQCP; 721809WQCP; K00587a; 13-((Dimethylamino)methyl)-10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H,13H-dibenzo(e,k)pyrrolo(3,4-h)(1,4,13)oxadiazacyclohexadecene-1,3(2H)-dione; CHEMBL432130; (9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-di(metheno)dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione; Br-WR99210
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| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
CGP-53353
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Terminated | Compound Info | ||
| Synonyms |
145915-60-2; CGP 53353; CGP-53353; DAPH 2; DAPH-7; CGP53353; PKCbetaII/EGFR Inhibitor; 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE; CHEMBL7939; CGP 53 353; 4,5-bis(4-Fluoroanilino)-phthalimide; CG53353; 5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione; 5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione; 4,5-Bis(4-fluoroanilino)phthalimide; 4,5-Bis[4-fluoroanilino]phthalimide; PKCbII/EGFR Inhibitor; AC1O8KXF; 5,6-bis(4-fluoroanilino)isoindole-1,3-dione; MolMap_000016; DAPH-2; CGP-53353, solid; SCHEMBL230492
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| Activity |
IC50 = 50000 nM
|
[7] | |||
| Compound Name |
1-Phenyl-1H-benzoimidazol-5-ol
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Investigative | Compound Info | ||
| Synonyms |
1-Phenyl-5-hydroxybenzimidazole; 1-phenyl-1H-Benzimidazol-5-ol; 69445-45-0; 1-Phenylbenzimidazole deriv. 65; AC1LDIKP; 1-phenylbenzimidazol-5-ol; CHEMBL80873; SCHEMBL4280861; BDBM3848; 5-hydroxy-1-phenylbenzimidazole; CTK5C9901; ZINC17525; DTXSID70349872; 1-Phenyl-1H-benzimidazole-5-ol; 1H-Benzimidazol-5-ol,1-phenyl-; OQAPWZCMAFFBBL-UHFFFAOYSA-N; 1-phenyl-1H-1,3-benzodiazol-5-ol; AKOS022650144; 5-Substituted 1-Phenylbenzimidazole 5; DA-04176; KB-219704; FT-0734974
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
1-Phenyl-1H-benzoimidazole
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Investigative | Compound Info | ||
| Synonyms |
1-Phenyl-1H-benzoimidazole; 2622-60-8; 1-phenyl-1H-benzo[d]imidazole; 1-phenylbenzimidazole; 1-Phenyl-1H-benzimidazole; 97542-80-8; 1H-Benzimidazole,1-phenyl-; BAS 00350928; 1H-Benzimidazole, 1-phenyl-; XNCMQRWVMWLODV-UHFFFAOYSA-N; 1-PHENYL-1H-1,3-BENZODIAZOLE; AK123264; AC1LCTXI; PubChem19972; 1-Phenyl benzoimidazole; 1-Phenylbenzimidazole 3; phenyl-1H- Benzimidazole; 1-phenyl-1,3-benzodiazole; MLS000765952; SCHEMBL157265; 1-Phenyl-1H-benzimidazole #; CHEMBL310080; BDBM3794; CTK4F7433; DTXSID10345732; 1-Phenylbenzimidazole deriv.
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
PMID19364658C33
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Investigative | Compound Info | ||
| Synonyms |
GTPL8163; BDBM50259563
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
5-Methoxy-1-phenyl-1H-benzoimidazole
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Investigative | Compound Info | ||
| Synonyms |
1H-Benzimidazole, 5-methoxy-1-phenyl-; 38205-85-5; 1-Phenylbenzimidazole deriv. 64; AC1NS4LX; CHEMBL76202; BDBM3847; SCHEMBL8006768; 5-methoxy-1-phenylbenzimidazole; CTK1B5049; DTXSID40416161; 5-Methoxy-1-phenyl-1H-benzimidazole; AKOS023169650; 5-Substituted 1-Phenylbenzimidazole 6
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
A-432411
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Investigative | Compound Info | ||
| Synonyms |
43A; (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE; 2ayp; indolinone analog 13; A-432411; CHEMBL202930; SCHEMBL6674605; BDBM14649; DB07078; 29690-EP2311842A2; 29690-EP2289868A1; 29690-EP2289894A2; (3Z)-6-(4-hydroxy-3-methoxyphenyl)-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one; (3Z)-6-(4-hydroxy-3-methoxyphenyl)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
4-(5-Methoxy-benzoimidazol-1-yl)-phenylamine
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Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 22; AC1NS4PO; SCHEMBL7989819; CHEMBL309035; BDBM3933; AKOS023129997; 4-(5-methoxybenzimidazol-1-yl)aniline; 5-Methoxy-1-(4-aminophenyl)-1H-benzimidazole; 4-(5-methoxy-1H-1,3-benzodiazol-1-yl)aniline; 1-(4-aminophenyl)-5-methoxybenzimidazole dihydrochloride
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
BUTEIN
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Investigative | Compound Info | ||
| Synonyms |
butein; 487-52-5; 2',3,4,4'-Tetrahydroxychalcone; 3,4,2',4'-Tetrahydroxychalcone; 2',4',3,4-Tetrahydroxychalcone; UNII-4WVS5M0LGF; EINECS 207-659-5; 4WVS5M0LGF; (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one; CHEMBL128000; CHEBI:3237; (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one; 1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one; ,3,4-Tetrahydroxychalcone; Chalcone, 2',3,4,4'-tetrahydroxy- (7CI,8CI); Acrylophenone, 2',4'-dihydroxy-3-(3,4-dihy
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| Activity |
IC50 = 65000 nM
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[11] | |||
| Compound Name |
8-chloro-quinoline-3-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL436817; Cyanoquinoline, 11; SCHEMBL6071997; BDBM21898; CHEBI:94979; BRD-K00088062-001-01-3; 4-[(3-Chloro-4-fluorophenyl)amino]-6-[(1H-imidazole-5-ylmethyl)amino]-8-chloro-3-quinolinecarbonitrile
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| Activity |
IC50 ~ 100000 nM
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[12] | |||
| Compound Name |
LY-326449
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Investigative | Compound Info | ||
| Synonyms |
LY-326449; CHEMBL292495; BDBM50052039; 3,4-[[(S)-3-Oxa-4-(hydroxymethyl)hexane-1,6-diyl]bis(1H-indole-1,3-diyl)]-3-pyrroline-2,5-dione
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| Activity |
IC50 ~ 100000 nM
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[6] | |||
| Compound Name |
3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL7827; SCHEMBL3355884; 62845-10-7; 3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one; CTK2B1467; ZINC23489; DTXSID10445847; BDBM50074745; AKOS030553076; 5,7-Dihydroxy-3-(3-chlorophenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 3-(3-chlorophenyl)-5,7-dihydroxy-
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| Activity |
IC50 ~ 100000 nM
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[13] | |||
| Compound Name |
5,6-Bis-p-tolylamino-isoindole-1,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL7914; 5,6-Bis-p-tolylamino-isoindole-1,3-dione; SCHEMBL8834183; BDBM50040920
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| Activity |
IC50 ~ 100000 nM
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[7] | |||
| Compound Name |
3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL481248; BDBM50259638
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
Pyrido[2,3-d]pyrimidin-7(8H)-one deriv. 6d
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Investigative | Compound Info | ||
| Synonyms |
BDBM4202; CHEMBL107177; 6-(2,6-dichlorophenyl)-2-{[2-(diethylamino)ethyl]amino}-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
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| Activity |
IC50 ~ 50000 nM
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[14] | |||
| Compound Name |
1-[2-Amino-6-(3,5-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
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Investigative | Compound Info | ||
| Synonyms |
PD089828 analog 17; CHEMBL81474; BDBM4836; SCHEMBL8130155; 1-[2-Amino-6-(3,5-dimethyl-phenyl)-pyrido[2,3-d]-pyrimidin-7-yl]-3-tert-butyl-urea; 1-[2-Amino-6-(3,5-dimethyl-phenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butyl-urea
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
N-[2-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-7-yl]-2,2,2-trifluoroacetamide
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Investigative | Compound Info | ||
| Synonyms |
1,6-naphthyridine deriv. 18; BDBM4616; CHEMBL134334; N'-(Trifluoroacetyl)-3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine
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| Activity |
IC50 ~ 50000 nM
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[15] | |||
| Compound Name |
5-Butoxy-1-phenylbenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 10; CHEMBL80510; BDBM3921; SCHEMBL7993339; 5-Butoxy-1-phenyl-1H-benzimidazole; 5-butoxy-1-phenyl-1H-1,3-benzodiazole; 5-butoxy-1-phenylbenzimidazole hydrochloride
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
3-(Dimethylamino)-1-(3-hydroxy-4-phenylmethoxyphenyl)propan-1-one;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL552860
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| Activity |
IC50 ~ 50000 nM
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[5] | |||
| Compound Name |
1-Methyl-2-methylsulfanyl-N-phenylindole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
1-Methyl-2-(methylthio)-N-phenyl-1H-indole-3-carboxamide; 2-thioxo-1H-indole-3-carboxamide deriv. 12; CHEMBL64814; BDBM4046; 1-methyl-2-(methylsulfanyl)-N-phenyl-1H-indole-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
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[16] | |||
| Compound Name |
N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL357756; CHEMBL3822972; BDBM206104; DB-085143; US9255110, 17
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| Activity |
IC50 ~ 50000 nM
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[17] | |||
| Compound Name |
PD089828 analog 31
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL50371; BDBM4850; 1-{2-amino-6-[3,5-bis(dimethylamino)phenyl]pyrido[2,3-d]pyrimidin-7-yl}-3-tert-butylurea; N-[2-Amino-6-[3,5-bis(dimethylamino)phenyl]pyrido[2,3-d]pyrimidine-7-yl]-N'-tert-butylurea
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
1-Phenyl-1H-benzimidazole-5-thiol
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Investigative | Compound Info | ||
| Synonyms |
1-phenyl-1h-benzo[d]imidazole-5-thiol; 1-phenylbenzimidazole-5-thiol; 5-Substituted 1-Phenylbenzimidazole 23; BDBM3934; CHEMBL419653; SCHEMBL7975709; DTXSID80416165; ZINC13798298; 1-phenyl-1H-1,3-benzodiazole-5-thiol; 5-Mercapto-1-phenylbenzimidazole Hydrochloride
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
PD158780 Analog 5h
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Investigative | Compound Info | ||
| Synonyms |
4-N-(3-bromophenyl)-6-N-[2-(dimethylamino)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine; BDBM3704; CHEMBL162034; 4-[(3-Bromophenyl)amino]-6-[[2-(dimethylamino)-ethyl]amino]pyrido[3,4-d]pyrimidine
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| Activity |
IC50 ~ 50000 nM
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[18] | |||
| Compound Name |
PD158780 Analog 5k
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Investigative | Compound Info | ||
| Synonyms |
BDBM3707; CHEMBL433520; 4-[(3-Bromophenyl)amino]-6-[[3-(diethylamino)-2-hydroxypropyl]amino]pyrido[3,4-d]pyrimidine; 4-N-(3-bromophenyl)-6-N-[3-(diethylamino)-2-hydroxypropyl]pyrido[3,4-d]pyrimidine-4,6-diamine
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| Activity |
IC50 ~ 50000 nM
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[18] | |||
| Compound Name |
Rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)propanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL591457; BDBM50306678
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| Activity |
IC50 ~ 50000 nM
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[19] | |||
| Compound Name |
Rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)acrylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL602470; BDBM50306685
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| Activity |
IC50 ~ 50000 nM
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[19] | |||
| Compound Name |
4',6-Diamino-5-hydroxyflavone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL116051; 4h-1-benzopyran-4-one,6-amino-2-(4-aminophenyl)-5-hydroxy-; BDBM50037405; ZINC13738764; 6-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one
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| Activity |
IC50 ~ 50000 nM
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[20] | |||
| Compound Name |
Di(1,3-dimethyl-1H-2-indolyl) disulfide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL158879; BDBM50036018
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| Activity |
IC50 ~ 50000 nM
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[21] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5m
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Investigative | Compound Info | ||
| Synonyms |
BDBM5074; CHEMBL336644
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| Activity |
IC50 = 50000 nM
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[22] | |||
| Compound Name |
7-(2,6-Dimethylphenyl)-5-methyl-N-(quinolin-8-yl)benzo[e][1,2,4]triazin-3-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL218160; SCHEMBL4268128; BDBM50193900; ZINC35816104; US8481536, 329; [7-(2,6-dimethyl-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-quinolin-8-yl-amine; [7-(2,6-dimethyl-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]quinolin-8-yl-amine; 7-(2,6-dimethylphenyl)-5-methyl-N-quinolin-8-yl-1,2,4-benzotriazin-3-amine
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| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
Methyl 4-(6-(4-(methoxycarbonylamino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
WYE-354; WYE 354; pyrazolo pyrimidine, 19; cc-506; MLS006011008; SCHEMBL300431; CHEMBL561708; GTPL9361; WYE354; BDBM35587; DTXSID00657912; C24H29N7O5; HMS3654N09; BCP02898; ZINC43013490; CCG-264882; CS-0183; SB19260; NCGC00242484-01; NCGC00242484-02; NCGC00242484-09; AC-28454; AS-55957; HY-12034; SMR004702806; BCP0726000260; DB-059456; FT-0675866; S1266; SW219671-1; X7422; W-5702; J-001552; J-514253; BRD-K77008974-001-01-6; Q27166532; mTOR Kinase Inhibitor II, WYE-354 - CAS 1062169-56-5
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| Activity |
IC50 ~ 50000 nM
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[24] | |||
| Compound Name |
3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1949788; SCHEMBL12134179; BDBM50364832; CH-4932748
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[25] | |||
| Compound Name |
Methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095626; SCHEMBL3984085; BDBM50316252; methyl 4-[6-(4-aminophenyl)-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[26] | |||
| Compound Name |
1-Isopropyl-3-(pyrimidin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL3616915; CHEMBL1241391; US9765037, Compound 18; BDBM340891; 1-propan-2-yl-3-pyrimidin-5-ylpyrazolo[3,4-d]pyrimidin-4-amine; 1-isopropyl-3-(pyrimidin-5-yl)-1H-pyrazolo[3,4- d]pyrimidin-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[27] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9p
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4198; CHEMBL323017; 3-(2,6-Dichlorophenyl)-7-[(4-methoxyphenyl)amino]-1-methyl-1,8-naphthyridin-2(1H)-one; 3-(2,6-dichlorophenyl)-7-[(4-methoxyphenyl)amino]-1-methyl-1,2-dihydro-1,8-naphthyridin-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
4-(3-((4-Hydroxy-3-oxobenzofuran-2(3H)-ylidene)methyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(2-hydroxyethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1092754; SCHEMBL4385411; BDBM50314344
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[28] | |||
| Compound Name |
3N-(3-Pyridyl)-1-methyl-2-[1-methyl-3-(3-pyridylcarbamoyl)-1H-2-indolyldisulfanyl]-1H-3-indolecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL352010; SCHEMBL8999317; BDBM50036007
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[21] | |||
| Compound Name |
1-[2-Amino-6-(2,3,4,5,6-pentamethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD089828 analog 20; CHEMBL78555; BDBM4839
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
[4-[2-[(Dimethylamino)methyl]prop-2-enoyl]phenyl] 4-(dimethylcarbamoyl)benzenesulfonate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL552634
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
1-Phenylbenzimidazol-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-Hydroxy-1-phenylbenzimidazole Hydrochloride; 1-Phenylbenzimidazole deriv. 56; 1-Phenylbenzimidazole 4; CHEMBL75964; BDBM3839; SCHEMBL7986692; 1-Phenyl-1H-benzimidazole-4-ol; 1-phenyl-1H-1,3-benzodiazol-4-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
1-[2-Amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL56236; 6-arylpyrido[2,3-d]pyrimidine deriv. 23; BDBM3441; SCHEMBL8135562; PD162628; 1-[2-Amino-6-(2,3,5,6-tetramethyl-phenyl)-pyrido-[2,3-d]pyrimidin-7-yl]-3-tert-butyl-urea; 1-[2-Amino-6-(2,3,5,6-tetramethyl-phenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butyl-urea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
[5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(6-phenyl-1H-indol-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3681244; SCHEMBL10003622; BDBM130832; BDBM50197687; US8829199, 74
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
7-Mesityl-5-methyl-N-phenylbenzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218109; SCHEMBL3746268; BDBM50193893; ZINC40576197; US8481536, 317; 5-methyl-N-phenyl-7-(2,4,6-trimethylphenyl)-1,2,4-benzotriazin-3-amine; [5-Methyl-7-(2,4,6-trimethyl-phenyl)-benzo[1,2,4]triazin-3-yl]-phenyl-amine; [5-Methyl-7-(2,4,6-trimethyl-phenyl)benzo[1,2,4]triazin-3-yl]-phenyl-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 19
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77242; BDBM3930; SCHEMBL7990149; 5-(2-Morpholinoethoxy)-1-phenyl-1H-benzimidazole; 4-{2-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]ethyl}morpholine; 5-[2-(4-morpholino)ethoxy]-1-phenylbenzimidazole dihydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
5-(Oxiran-2-ylmethoxy)-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-(2,3-Epoxypropoxy)-1-phenylbenzimidazole; 5-Substituted 1-Phenylbenzimidazole 13; BDBM3924; CHEMBL310726; SCHEMBL7989348; 5-(Oxiranylmethoxy)-1-phenyl-1H-benzimidazole; 5-(oxiran-2-ylmethoxy)-1-phenyl-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
(2S)-1-(1H-Indol-3-yl)-3-(5-isoquinolin-6-ylpyridin-3-yl)oxy-propan-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
isoquinoline-pyridine, 1; isoquinoline-pyridine, 3; 5-isoquinolinyl pyridine 2; pyridine-base inhibitor 13a; CHEMBL383264; SCHEMBL6855488; BDBM15067; 13a (S-); 6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridin-3-yl}isoquinoline
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[30] | |||
| Compound Name |
Rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)-N-methylacrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598912; BDBM50306680
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[19] | |||
| Compound Name |
1-Phenylbenzimidazole-5,6-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 36; BDBM3947; CHEMBL311449; SCHEMBL7993203; 1-Phenyl-1H-benzimidazole-5,6-diol; 1-phenyl-1H-1,3-benzodiazole-5,6-diol; 5,6-dihydroxy-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
6-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]quinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598727; CH-5192751
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[19] | |||
| Compound Name |
1-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-3-ethylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,6-naphthyridine deriv. 14; BDBM4612; CHEMBL422625; N-(Ethylcarbamoyl)-3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine; N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-N-ethylurea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 26
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3937; CHEMBL309270; 1-Phenyl-1H-benzimidazole-5-ol dimethylthiocarbamate; N,N-dimethyl-1-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]methanethioamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(3Ar)-13,13,16-Trimethyl-15-Oxo-1,2,3,3a,4,5,12,14,15,17,18,19-Dodecahydro-13h-10,6-(Metheno)pyrrolo[2',1':3,4][1,4,9]triazacyclotetradecino[9,8-A]indole-7-Carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1738705; BDBM50345150; Q27449875
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
Wee1 Inhibitor
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Wee1 Inhibitor I; CHEMBL379975; 4-(2-Chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3-(2H,6H)-dione; Kinome_3672; SCHEMBL5828030; CTK8F1059; DTXSID70439085; HMS3229P19; BDBM50192371; 2-(2-Chlorophenyl)-6-hydroxy-9H-carbazole-3,4-dicarbimide; 4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione; 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[32] | |||
| Compound Name |
4-[[4-[2-Methylene-3-(dimethylamino)propionyl]phenoxy]sulfonyl]salicylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL310580; BDBM50031659; 4-[4-(2-Dimethylaminomethyl-acryloyl)-phenoxysulfonyl]-2-hydroxy-benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[5] | |||
| Compound Name |
1-Phenyl-5-propoxybenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 8; CHEMBL78444; BDBM3919; SCHEMBL7992992; 5-Propoxy-1-phenyl-1H-benzimidazole; 1-phenyl-5-propoxy-1H-1,3-benzodiazole; 1-phenyl-5-propoxybenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Methyl 2-oxo-2-[[3-[5-(3-phenoxyprop-1-ynyl)thiophen-3-yl]-1,4-dihydroindeno[1,2-c]pyrazol-5-yl]amino]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL246166; BDBM50209148
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
4',6,8-Triamino-7-hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL115601; BDBM50037409; 6,8-Diamino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
2-(1-Phenylbenzimidazol-5-yl)oxyethanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 15; BDBM3926; CHEMBL311777; SCHEMBL7989532; 5-(2-Aminoethoxy)-1-phenyl-1H-benzimidazole; 5-(2-aminoethoxy)-1-phenyl-1H-1,3-benzodiazole; 5-(2-aminoethoxy)-1-phenylbenzimidazole dihydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1949789; SCHEMBL12134185; BDBM50364833; CH-4932750
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[25] | |||
| Compound Name |
1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quinoxaline-6,8-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL266255; BDBM50040913; 1,4-Diphenyl-1,2,3,4-tetrahydroquinoxaline-6,7-dicarbimide; 1,4-diphenyl-2,3-dihydropyrrolo[3,4-g]quinoxaline-6,8-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
[5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(6-bromo-1H-indol-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3676329; SCHEMBL10003722; BDBM130815; BDBM50197712; US8829199, 48
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
3-{[(1R)-1-Phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466496; SCHEMBL4365652; BDBM50259376; DB07234; Q27096459; 3-((R)-1-Phenyl-ethylamino)-4-(pyridin-4-ylamino)-cyclobut-3-ene-1,2-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 32
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3943; CHEMBL310243; SCHEMBL7991043; 4-bromo-5-allyloxy-1-phenylbenzimidazole; 4-bromo-1-phenyl-5-(prop-2-en-1-yloxy)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
6-Methoxy-3-phenylbenzimidazole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 40; CHEMBL80171; BDBM3951; SCHEMBL7986304; 5-methoxy-1-phenylbenzimidazole-6-carboxylic acid; 5-methoxy-1-phenyl-1H-1,3-benzodiazole-6-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
CID 49806721
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1823221; SCHEMBL896410; BDBM50352760; 9-ethyl-6,6-dimethyl-8-[4-(oxetan-3-yl)piperazin-1-yl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[34] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4194; CHEMBL107372; 1-Methyl-7-amino-3-(2,6-dichlorophenyl)-1,8-naphthyridine-2(1H)-one; 7-Amino-3-(2,6-dichlorophenyl)-1-methyl-1,8-naphthyridin-2(1H)-one; 7-amino-3-(2,6-dichlorophenyl)-1-methyl-1,2-dihydro-1,8-naphthyridin-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
7-Hydroxy-2-[[7-hydroxy-1-methyl-3-(phenylcarbamoyl)indol-2-yl]disulfanyl]-1-methyl-N-phenylindole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
dithiobis(1H-indole-3-carboxamide) deriv. 10y; CHEMBL62843; BDBM4040; SCHEMBL8998776
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[16] | |||
| Compound Name |
1-Methyl-2-[[1-methyl-3-(thiophen-2-ylcarbamoyl)indol-2-yl]disulfanyl]-N-thiophen-2-ylindole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL345622; SCHEMBL8999355; BDBM50035997
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[21] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 20
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL80915; BDBM3931; SCHEMBL7986193; 5-(3-Morpholinopropoxy)-1-phenyl-1H-benzimidazole; 4-{3-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]propyl}morpholine; 5-[3-(4-Morpholino)propoxy]-1]phenylbenzimidazole Dihydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1081198; SCHEMBL5480112; BDBM50312153
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[35] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 11
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3922; CHEMBL311318; SCHEMBL7989555; 5-(Allyloxy)-1-phenyl-1H-benzimidazole; 5-allyloxy-1-phenylbenzimidazole hydrochloride; 1-phenyl-5-(prop-2-en-1-yloxy)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2-Thioxo-1H-indole-3-carboxamide deriv. 11
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63009; BDBM4045; 1,3-dimethyl-N-phenyl-2-thioxoindoline-3-carboxamide; 1,3-dimethyl-N-phenyl-2-sulfanylidene-2,3-dihydro-1H-indole-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[16] | |||
| Compound Name |
N-(3-Bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
bpiq-ii; CHEMBL66031; Imidazoquinazoline deriv. 8; Anilinopyrimidine deriv. 7a; BDBM3570; SCHEMBL13898313; CTK0E4714; 8-[(3-Bromophenyl)amino]-1H-imidazo[4,5-g]-quinazoline; DTXSID20274367; ZINC3815028; HSCI1_000062; SC-91510; BRD-K35473459-001-01-7; N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-am; 8-[(3-Bromophenyl)amino]-1H-imidazo[4,5-g]quinazoline; 1H-Imidazo[4,5-g]quinazolin-8-amine, N-(3-bromophenyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
7-Phenylbenzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218411; 1,2,4-Benzotriazin-3-amine,7-phenyl-; BDBM50193905
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
2-[(Dimethylamino)methyl]-1-(4-phenylmethoxyphenyl)-3-phenylsulfanylpropan-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540292
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
6-{5-[(2S)-2-Amino-3-(1H-indol-3-yl)propoxy]-2-ethynylpyridin-3-yl}isoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Isoquinoline-pyridine, 10e; CHEMBL207544; SCHEMBL6857580; BDBM16958; (2S)-1-(6-ethynyl-5-isoquinolin-6-ylpyridin-3-yl)oxy-3-(1H-indol-3-yl)propan-2-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[37] | |||
| Compound Name |
4,5-Bis(cyclohexylamino)phthalimide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL266969; 5,6-bis(cyclohexylamino)isoindole-1,3-dione; SCHEMBL8834712; BDBM50040912; 5,6-Bis-cyclohexylamino-isoindole-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
4,5-Dimethoxy-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 30; CHEMBL80558; BDBM3941; SCHEMBL7989444; 4,5-dimethoxy-1-phenyl-1H-1,3-benzodiazole; 4,5-dimethoxy-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2-[(Dimethylamino)methyl]-1-(3-hydroxy-4-phenylmethoxyphenyl)prop-2-en-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL542887
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||||
| Activity |
IC50 = 50000 nM
|
[5] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9h
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4196; CHEMBL104532; 3-(2,6-Dichlorophenyl)-1-methyl-7-[[3-(4-methylpiperazinyl)propyl]amino]-1,8-naphthyridin-2(1H)-one
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
1,6-Naphthyridine deriv. 19
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4617; CHEMBL135074; N,N'-Bis(tert-butylcarbamoyl)-3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine; 3-tert-butyl-1-{7-[(tert-butylcarbamoyl)amino]-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl}urea; N-(tert-Butyl)-N-[7-(3-tert-butylureido)-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]urea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
3-[4-(3-Amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-(3-chlorophenyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Aminobenzoisoxazole, 51; SCHEMBL420822; CHEMBL269884; BDBM21105; 1-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-3-(3-chlorophenyl)urea
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[38] | |||
| Compound Name |
3',6-Diamino-7-hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL115102; 4h-1-benzopyran-4-one,6-amino-2-(3-aminophenyl)-7-hydroxy-; BDBM50037397; ZINC13738769; 6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
6-Methoxy-3-phenylbenzimidazole-5-carbaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 44; CHEMBL76962; BDBM3955; SCHEMBL7988898; 5-methoxy-1-phenyl-1H-1,3-benzodiazole-6-carbaldehyde; 5-methoxy-1-phenylbenzimidazole-6-carboxaldehyde hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
4',8-Diamino-6-methoxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL116353; BDBM50037401; 8-Amino-2-(4-amino-phenyl)-6-methoxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
2-(2-Methoxy-ethoxy)-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen-3-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL245968; BDBM50209144
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 33
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3944; CHEMBL307817; 4-Allyl-5-hydroxy-1-phenylbenzimidazole; 1-phenyl-4-(prop-2-en-1-yl)-1H-1,3-benzodiazol-5-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(2E)-2-[(3,5-Dibromo-4-hydroxyphenyl)methylidene]-5-methoxyindene-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL82560; BDBM50071677; 2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylidene]-5-methoxy-indan-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[39] | |||
| Compound Name |
5-Methylsulfanyl-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 24; CHEMBL80810; BDBM3935; SCHEMBL7993237; ZINC3815798; 5-(Methylthio)-1-phenyl-1H-benzimidazole; 5-(methylsulfanyl)-1-phenyl-1H-1,3-benzodiazole; 5-(methylthio)-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
3-[4-(4-Hydroxyphenyl)phenyl]-N-(pyridin-4-ylmethyl)-1,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL242753; SCHEMBL6794625; BDBM50204693
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[40] | |||
| Compound Name |
3-[[2-(2-Fluorophenyl)pyridin-4-yl]amino]-4-[[(1R)-1-phenylethyl]amino]cyclobut-3-ene-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468125; 3-{[2-(2-Fluorophenyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione; SCHEMBL4371574; BDBM50259601
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
4',8-Diamino-5-methoxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL115397; BDBM50037396; 8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
3-(4'-Hydroxybiphenyl-4-Yl)-N-(4-Hydroxycyclohexyl)-1,4-Dihydroindeno[1,2-C]pyrazole-6-Carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL438485; SCHEMBL4809259; SCHEMBL4809267; BDBM91830; BDBM50204694; ZINC100469705; ZINC253994709; Q27456666
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[40] | |||
| Compound Name |
1-[2-Amino-6-(3,5-diethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD089828 analog 23; BDBM4842; CHEMBL445893
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-3-methylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,6-naphthyridine deriv. 13; BDBM4611; CHEMBL134801; N-(Methylcarbamoyl)-3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine; N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-N-methylurea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL519113; SCHEMBL4366875; BDBM50259637; 3-[[2-(furan-2-yl)pyridin-4-yl]amino]-4-[[(1R)-1-phenylethyl]amino]cyclobut-3-ene-1,2-dione
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
3-(1-Phenylbenzimidazol-5-yl)oxypropane-1,2-diol
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 14; BDBM3925; CHEMBL310137; SCHEMBL7975765; 5-(2,3-Dihydroxypropoxy)-1-phenyl-1H-benzimidazole; 3-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]propane-1,2-diol; 5-(2,3-dihydroxypropoxy)-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
4',8-Diamino-7-hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL114568; 4h-1-benzopyran-4-one,8-amino-2-(4-aminophenyl)-7-hydroxy-; BDBM50037407; ZINC13738766; 8-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
1,2,4-Benzotriazin-3-amine,7-(2-chlorophenyl)-5-methyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376052; BDBM50193917; 7-(2-chlorophenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
1-[2-Amino-6-(3,4-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD089828 analog 27; CHEMBL78802; BDBM4846
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-(4-Methyl-piperazin-1-yl)-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen-3-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL245377; SCHEMBL4820003; BDBM50209158
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9n
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4197; CHEMBL420473; 3-(2,6-dichlorophenyl)-1-methyl-7-(phenylamino)-1,2-dihydro-1,8-naphthyridin-2-one; 3-(2,6-Dichlorophenyl)-1-methyl-7-(phenylamino)-1,8-naphthyridin-2(1H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
1-[2-Amino-6-(4-methoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD089828 analog 26; BDBM4845; CHEMBL312055
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
1-Phenyl-5-propan-2-yloxybenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 9; CHEMBL79328; BDBM3920; SCHEMBL7975892; 5-Isopropoxy-1-phenyl-1H-benzimidazole; 5-isopropoxy-1-phenylbenzimidazole hydrochloride; 1-phenyl-5-(propan-2-yloxy)-1H-1,3-benzodiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
7-(2,6-Dimethylphenyl)-5-methyl-N-(pyridin-2-yl)benzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218738; SCHEMBL4275225; BDBM50193878; ZINC35899981; US8481536, 330; 7-(2,6-dimethylphenyl)-5-methyl-N-pyridin-2-yl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
4',8-Diaminoflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL323660; 4h-1-benzopyran-4-one,8-amino-2-(4-aminophenyl)-; BDBM50037410; ZINC13738757; 8-Amino-2-(4-amino-phenyl)-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
Tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095627; SCHEMBL3991434; BDBM50316253
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[26] | |||
| Compound Name |
6-Methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1080995; SCHEMBL2934911; BDBM50311954
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[41] | |||
| Compound Name |
3-(2,6-Dichlorophenyl)-7-(dimethylamino)-1-methyl-1,6-naphthyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,6-naphthyridin-2(1H)-one deriv. 7c; BDBM4170; CHEMBL108170; SCHEMBL6638893; 1-Methyl-7-(dimethylamino)-3-(2,6-dichlorophenyl)-1,6-naphthyridine-2(1H)-one; 3-(2,6-dichlorophenyl)-7-(dimethylamino)-1-methyl-1,2-dihydro-1,6-naphthyridin-2-one; 3-(2,6-Dichlorophenyl)-7-(dimethylamino)-1-methyl-1,6-naphthyridin-2(1H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
2-{[3,4-Dioxo-2-(pyridin-4-ylamino)cyclobut-1-en-1-yl]amino}-2-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467079; SCHEMBL4379540; BDBM50259532; 2-[[3,4-dioxo-2-(pyridin-4-ylamino)cyclobuten-1-yl]amino]-2-phenylacetamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
4',8-Diamino-5-hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL114578; BDBM50037402; 8-Amino-2-(4-amino-phenyl)-5-hydroxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
5-Methoxy-6-methyl-1-phenylbenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 38; CHEMBL77712; BDBM3949; SCHEMBL7986240; 1-Phenyl-5-methoxy-6-methyl-1H-benzimidazole; 5-methoxy-6-methyl-1-phenyl-1H-1,3-benzodiazole; 5-methoxy-6-methyl-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-(4-Butylphenyl)-7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218842; SCHEMBL4265944; BDBM50193888; ZINC38268153; US8481536, 341; N-(4-butylphenyl)-7-(2,6-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
1-[2-Amino-6-(3,5-diethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL48809; PD089828 analog 30; BDBM4849; N-[2-Amino-6-(3,5-diethoxyphenyl)pyrido[2,3-d]pyrimidine-7-yl]-N'-tert-butylurea
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N6,N6-Dimethyl-N4-[1-(phenylmethyl)-5-indazolyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
GW2974; EGFR/HER2 Inhibitor; CHEMBL30432; GW282974X; 4-N-(1-benzylindazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine; Lopac-G-0668; Lopac0_000509; SCHEMBL1737530; CTK8E8381; DTXSID40424963; HMS3261F19; HMS3303J07; HMS3305C14; Tox21_500509; BDBM50099963; GW-974; MFCD04974495; ZINC18371391; CCG-204600; LP00509; SDCCGSBI-0050493.P002; KS-0000183M; SMP2_000268; SMP2_000301; NCGC00015468-01; NCGC00015468-02; NCGC00015468-03; NCGC00015468-04; NCGC00015468-05; NCGC00015468-06; NCGC00015468-07; NCGC00093907-01; NCGC00093907-02; NCGC00261194-01; GW2974, >=98% (HPLC), solid; EU-0100509; G 0668; AB01092265-01; SR-01000075892; J-013131; SR-01000075892-1; Q27167122
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[42] | |||
| Compound Name |
4-Methoxy-1-phenylbenzimidazol-5-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 29; BDBM3940; CHEMBL308385; SCHEMBL7975839; 5-hydroxy-4-methoxy-1-phenylbenzimidazole; 4-methoxy-1-phenyl-1H-1,3-benzodiazol-5-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
6-(3,5-Dimethoxyphenyl)pyrido[2,3-d]pyrimidine-2,7-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-arylpyrido[2,3-d]pyrimidine deriv. 24; CHEMBL56942; BDBM3442; SCHEMBL5619571; 6-(3,5-Dimethoxy-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine; ZINC13834860; FT-0667379
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
4',6-Diamino-7-hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL432416; 4h-1-benzopyran-4-one,6-amino-2-(4-aminophenyl)-7-hydroxy-; 6,4'-diamino-7-hydroxyflavone; BDBM50037408; ZINC13738758; 6-Amino-2-(4-amino-phenyl)-7-hydroxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 34
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75637; BDBM3945; 4,5-Dihydro-5-methyl-1-phenylfuro[3,2-e]benzimidazole Hydrochloride; 11-methyl-5-phenyl-10-oxa-3,5-diazatricyclo[7.3.0.0^{2,6}]dodeca-1,3,6,8-tetraene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
1,6-naphthyridine deriv. 12; BDBM4610; CHEMBL133604
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
2-[9-(4-Amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-3-yl]-N-(4-morpholin-4-ylphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL395080; BDBM50218700
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[43] | |||
| Compound Name |
1,8-Naphthyridin-2(1H)-one deriv. 9e
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4195; CHEMBL107247; 3-(2,6-Dichlorophenyl)-7-[[3-(diethylamino)propyl]amino]-1-methyl-1,8-naphthyridin-2(1H)-one
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
PD158780 Analog 5n
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3710; CHEMBL162622; PD-0165557; 4-[(3-Bromophenyl)amino]-6-[[2-(4-morpholino)ethyl]amino]pyrido[3,4-d]pyrimidine; 4-N-(3-bromophenyl)-6-N-[2-(morpholin-4-yl)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
N-(2,3-Dimethylphenyl)-7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218551; SCHEMBL4273712; BDBM50193875; ZINC38224650; US8481536, 334; N-(2,3-dimethylphenyl)-7-(2,6-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
N-(7-(2,6-Dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL221739; SCHEMBL4271776; BDBM50193896; ZINC40584425; US8481536, 327; N-[7-(2,6-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-yl]acetamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
PD089828 analog 12
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL49658; BDBM4831; 1-{2-amino-6-[3,5-bis(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-yl}-3-tert-butylurea; N-[2-Amino-6-[3,5-bis(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidine-7-yl]-N'-tert-butylurea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1089082; SCHEMBL4656083; BDBM50314051; N-(3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[44] | |||
| Compound Name |
3',6-Diaminoflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL115103; 4h-1-benzopyran-4-one,6-amino-2-(3-aminophenyl)-; BDBM50037399; ZINC13738768; 6-Amino-2-(3-amino-phenyl)-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
7-((1H-1,2,4-Triazol-1-yl)methyl)-3-(5-(3-(2-methoxyethoxy)-prop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL223971; SCHEMBL17004664; BDBM50210271
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[45] | |||
| Compound Name |
1,6-Naphthyridine deriv. 20
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,6-naphthyridine 14; BDBM4618; CHEMBL339856
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
(3Z)-6-(4-Hydroxy-3-methoxyphenyl)-3-(1H-imidazol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
indolinone analog 29; CHEMBL199299; BDBM14665
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
1,6-Naphthyridine deriv. 16
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4614; CHEMBL134066; 3-[7-amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-1-phenylurea; N-(Phenylcarbamoyl)-3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine; N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-N-phenylurea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
3-[4-(3-Amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-[3-(trifluoromethyl)phenyl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Aminobenzoisoxazole, 50; SCHEMBL425740; CHEMBL430090; BDBM21104; 1-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[38] | |||
| Compound Name |
4-Bromo-1-phenylbenzimidazol-5-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-Bromo-5-Hydroxy-1-phenylbenzimidazole hydrochloride; 5-Substituted 1-Phenylbenzimidazole 31; CHEMBL76839; BDBM3942; SCHEMBL7989967; 4-bromo-1-phenyl-1H-1,3-benzodiazol-5-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N,N-Dimethyl-4-(1-phenylbenzimidazol-5-yl)oxybutan-1-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 18; CHEMBL78698; BDBM3929; SCHEMBL7989900; 5-[4-(Dimethylamino)butoxy]-1-phenyl-1H-benzimidazole; dimethyl({4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl})amine; 5-[4-(N,N-Dimethylamino)butoxy]-1-phenylbenzimidazole Dihydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
4',6,8-Triaminoflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL112422; BDBM50037394; 6,8-Diamino-2-(4-amino-phenyl)-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
1-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,6-naphthyridine deriv. 15; BDBM4613; CHEMBL134354; N-(tert-Butylcarbamoyl)-3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine; N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-N-tert-butylurea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
(1S)-2-(1H-Indol-3-YL)-1-[({5-[(E)-2-pyridin-4-ylvinyl]pyridin-3-YL}oxy)methyl]ethylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
bispyridinylethylene, 2; pyridine-base inhibitor 1b; CHEMBL383541; SCHEMBL6853457; BDBM15022; trans-bispyridinylethylene analog 2q; Q27096021
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[30] | |||
| Compound Name |
(E)-3-[6-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598911; CH-5201927
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[19] | |||
| Compound Name |
1-[2-Amino-6-(3-ethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD089828 analog 29; CHEMBL78485; BDBM4848
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Substituted 1-Phenylbenzimidazole 25
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3936; CHEMBL443800; 4-{3-[(1-phenyl-1H-1,3-benzodiazol-5-yl)sulfanyl]propyl}morpholine; 5-[(3-(4-Morpholino)propyl)thio]-1-phenylbenzimidazole Dihydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
7-(2,6-Dimethylphenyl)-N-(2-methoxyphenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376860; SCHEMBL4264635; BDBM50193911; ZINC35906977; US8481536, 342; 7-(2,6-dimethylphenyl)-N-(2-methoxyphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
3',8-Diamino-6-methoxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL114550; BDBM50037392; 8-Amino-2-(3-amino-phenyl)-6-methoxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
9-Hydroxy-4-phenylpyrrolo[3,4-C]carbazole-1,3(2H,6H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD 407824; PD-407824; 9-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONE; PD0407824; CHEMBL214253; PD407824; SCHEMBL6516584; CTK2C3047; DTXSID40402483; HMS3262B15; HMS3269N21; HMS3413B22; HMS3677B22; ZINC6475935; Tox21_500807; BDBM50192349; MFCD09753286; AKOS024457242; CCG-222111; DB04608; NCGC00167836-01; NCGC00167836-04; NCGC00261492-01; HY-18961; CS-0014679; FT-0673544; PD-407824, >=98% (HPLC); BRD-K82823804-001-01-7; Q27095347; 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione; Pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione, 9-hydroxy-4-phenyl-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[46] | |||
| Compound Name |
N-(2,4-Dimethylphenyl)-7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL441545; SCHEMBL4271618; BDBM50193914; ZINC40828426; US8481536, 335; N-(2,4-dimethylphenyl)-7-(2,6-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
N-(2,5-Dimethylphenyl)-7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL374868; SCHEMBL4271769; BDBM50193906; ZINC35858918; US8481536, 336; N-(2,5-dimethylphenyl)-7-(2,6-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[23] | |||
| Compound Name |
1-(2-Amino-6-phenylpyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76599; PD089828 analog 4; 1-{2-amino-6-phenylpyrido[2,3-d]pyrimidin-7-yl}-3-tert-butylurea; BDBM4823; SCHEMBL8130610; ZINC13763794; SC-49037; 1-(2-Amino-6-phenyl-pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butyl-urea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
1-Methyl-2-[[1-methyl-3-(pyridin-4-ylcarbamoyl)indol-2-yl]disulfanyl]-N-pyridin-4-ylindole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL156281; SCHEMBL8998915; BDBM50036002
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[21] | |||
| Compound Name |
6-Methyl-1-phenylbenzimidazol-5-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 39; BDBM3950; CHEMBL311913; SCHEMBL7989577; 1-Phenyl-6-methyl-1H-benzimidazole-5-ol; 6-methyl-1-phenyl-1H-1,3-benzodiazol-5-ol; 5-hydroxy-6-methyl-1-phenylbenzimidazole hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
7-Phenyl-[1,3]dioxolo[4,5-f]benzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Substituted 1-Phenylbenzimidazole 37; CHEMBL80651; BDBM3948; SCHEMBL7986233; 7-Phenyl-7H-1,3-dioxolo[4,5-f]benzimidazole; 5,6-methylenedioxy-1-phenylbenzimidazole hydrochloride; 12-phenyl-4,6-dioxa-10,12-diazatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),8,10-tetraene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Ethyl 3-oxo-3-[[3-[5-(3-phenoxyprop-1-ynyl)thiophen-3-yl]-1,4-dihydroindeno[1,2-c]pyrazol-5-yl]amino]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL395427; BDBM50209156
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
3-[4-(3-Amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Aminobenzoisoxazole, 49; SCHEMBL419044; CHEMBL270084; BDBM21103; 1-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[38] | |||
| Compound Name |
4',8-Diamino-6-hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL112421; BDBM50037406; 8-Amino-2-(4-amino-phenyl)-6-hydroxy-chromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
(6-Methoxy-3-phenylbenzimidazol-5-yl)methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-Hydroxymethyl-5-methoxy-1-phenylbenzimidazole hydrochloride; 5-Substituted 1-Phenylbenzimidazole 43; BDBM3954; CHEMBL306184; SCHEMBL7987204; ZINC3832252; (5-methoxy-1-phenyl-1H-1,3-benzodiazol-6-yl)methanol
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
4',5,7-Triamino-6-hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL114814; CTK4C9734; 5,7,4'-triamino-6-hydroxyflavone; BDBM50037395; 5,7-Diamino-2-(4-amino-phenyl)-6-hydroxy-chromen-4-one; 4H-1-Benzopyran-4-one,5,7-diamino-2-(4-aminophenyl)-6-hydroxy-, hydrochloride (1:3)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
Rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)-N,N-dimethylacrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL608738; BDBM50306679
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[19] | |||
| Compound Name |
N,alpha-Diphenyl-N-methyl-1H-indole-3-methaneamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779738; BDBM50345171; N-((1h-indol-3-yl)(phenyl)methyl)-N-methylaniline; N-((1H-Indol-3-yl)(phenyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 50600 nM
|
[47] | |||
| Compound Name |
2-(3-Chlorophenyl)-3-(3,4-dichlorophenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933738; BDBM50360642
Click to Show/Hide
|
||||
| Activity |
IC50 = 50700 nM
|
[48] | |||
| Compound Name |
Dithiobis(1H-indole-3-alkanoic acid) deriv. 27
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL79704; BDBM3979; 2,2 -Dithiobis(1H-indole-3-propanoic acid); 2,2'-Dithiobis(1H-indole-3-propanoic acid); 3-(2-{[3-(2-carboxyethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[49] | |||
| Compound Name |
4-(4-Fluorophenyl)-2-phenyl-5-pyridin-4-ylpyrazol-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011292; SCHEMBL14833476; BDBM50379228; 4-(4-Fluorophenyl)-1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-5-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[50] | |||
| Compound Name |
N-[4-Methyl-3-[(E)-2-[6-(methylamino)purin-9-yl]ethenyl]phenyl]-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL558475; SCHEMBL4124493; SCHEMBL4124500; BDBM50294016; (E)-N-(4-Methyl-3-(2-(6-(methylamino)-9H-purin-9-yl)vinyl)phenyl)-3-(trifluoromethyl)benzamide; (E)-N-(4-Methyl-3-(2-(6-(methylamino)-9Hpurin-9-yl)vinyl)phenyl)-3-(trifluoromethyl)-benzamide; N-[3-[2-[6-(Methylamino)-9H-purine-9-yl]ethenyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[51] | |||
| Compound Name |
3-[(2S,5S,8S,11S,14S,17S,20S,23S)-8,14,20-Tris(2-carboxyethyl)-5,11,17,23-tetrakis[3-(diaminomethylideneamino)propyl]-3,6,9,12,15,18,21,24-octaoxo-1,4,7,10,13,16,19,22-octazacyclotetracos-2-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2382012
Click to Show/Hide
|
||||
| Activity |
IC50 = 52600 nM
|
[52] | |||
| Compound Name |
N-{1-[3-(3,4-Dichloro-benzyl)-[1,2,4]oxadiazol-5-yl]-ethyl}-3-(4-phosphonooxy-benzyl)-succinamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL102765; BDBM50082327
Click to Show/Hide
|
||||
| Activity |
IC50 = 53000 nM
|
[53] | |||
| Compound Name |
Cot inhibitor-2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Wyeth Cot Inhibitor 2; C26H25Cl2FN8; CHEMBL527026; SCHEMBL4962096; BDBM29923; DTXSID50657644; HMS3295K05; 3403AH; MFCD13184702; ZINC42921365; NCGC00273985-02; NCGC00273985-03; NCGC00273985-04; HY-32018; DB-015004; FT-0759876; W-5556; substituted 6-aminoquinoline-3-carbonitrile, 34; 363Q563; BRD-K49468759-001-01-8; Q27163268
Click to Show/Hide
|
||||
| Activity |
IC50 = 53000 nM
|
[54] | |||
| Compound Name |
4-(4-Fluorophenyl)-2-(4-methylphenyl)-5-pyridin-4-ylpyrazol-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011296; SCHEMBL14839391; BDBM50379216
Click to Show/Hide
|
||||
| Activity |
IC50 = 53000 nM
|
[50] | |||
| Compound Name |
N-{1-[3-(3,4-Dichloro-benzyl)-[1,2,4]oxadiazol-5-yl]-2-hydroxy-ethyl}-3-(4-phosphonooxy-benzyl)-succinamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL102766; BDBM50082328
Click to Show/Hide
|
||||
| Activity |
IC50 = 54000 nM
|
[53] | |||
| Compound Name |
Ca-YEEIE
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327820; BDBM50118659; N-(3,4-Dihydroxy-trans-cinnamoyl)-L-Tyr-L-Glu-L-Glu-L-Ile-L-Glu-OH
Click to Show/Hide
|
||||
| Activity |
IC50 = 54000 nM
|
[55] | |||
| Compound Name |
(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-N-[(2S)-1-[[(3S,6S,9S)-3,6-bis[(4-hydroxyphenyl)methyl]-2,5,8-trioxo-1,4,7-triazacyclotridec-9-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-3-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791364; BDBM50370719
Click to Show/Hide
|
||||
| Activity |
IC50 = 54500 nM
|
[56] | |||
| Compound Name |
Ca-DOPA-EEIE
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328034; BDBM50118654; N-(3,4-Dihydroxy-trans-cinnamoyl)-3-hydroxy-L-Tyr-L-Glu-L-Glu-L-Ile-L-Glu-OH
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[55] | |||
| Compound Name |
[4-[[(3S,6R,9S,12R,15S,22R)-6-(2-Amino-2-oxoethyl)-15-(ethanethioylamino)-2,5,8,11,14,21-hexaoxo-3,9-di(propan-2-yl)-1,4,7,10,13,20-hexazabicyclo[20.3.0]pentacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433805; BDBM50074715
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[57] | |||
| Compound Name |
5-Amino-3-pyridin-4-yl-1-(2,4,6-trichlorophenyl)pyrazole-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011302; SCHEMBL14833637; BDBM50379220; 5-Amino-3-(pyridine-4-yl)-1-(2,4,6-trichlorophenyl)-1H-pyrazole-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[50] | |||
| Compound Name |
3-Cyclohexyl-2-(4-methylphenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933755; BDBM50360660
Click to Show/Hide
|
||||
| Activity |
IC50 = 57700 nM
|
[48] | |||
| Compound Name |
N-((1H-Indol-3-yl)(3-nitrophenyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779746; BDBM50345179
Click to Show/Hide
|
||||
| Activity |
IC50 = 58300 nM
|
[47] | |||
| Compound Name |
2-(3-Chlorophenyl)-3-cyclohexyl-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933754; BDBM50360659
Click to Show/Hide
|
||||
| Activity |
IC50 = 58400 nM
|
[48] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 13c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5103; CHEMBL336949
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[22] | |||
| Compound Name |
PharmaGSID_48505
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1258821; DSSTox_CID_28479; DSSTox_RID_82757; DSSTox_GSID_48505; DTXSID0048505; HMS3401P15; Tox21_303517; BDBM50328255; NCGC00257389-01
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[58] | |||
| Compound Name |
N-Methyl-N-((1-methyl-1H-indol-3-yl)(p-tolyl)methyl)benzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779745; BDBM50345178; N-Phenyl-N,1-dimethyl-alpha-(4-methylphenyl)-1H-indole-3-methaneamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 60500 nM
|
[47] | |||
| Compound Name |
2,3,7,8-Tetrahydroxy-5-[(4-nitrophenyl)methyl]phenanthridin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Phenanthridinone deriv. 5h; CHEMBL71205; BDBM4086; SCHEMBL7987368; 2,3,7,8-Tetrahydroxy-5-(4-nitrobenzyl)phenanthridin-6(5H)-one; 2,3,7,8-tetrahydroxy-5-[(4-nitrophenyl)methyl]-5,6-dihydrophenanthridin-6-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 61000 nM
|
[59] | |||
| Compound Name |
(S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-[3-(3-methyl-butyl)-[1,2,4]oxadiazol-5-yl]-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76813; BDBM50080192
Click to Show/Hide
|
||||
| Activity |
IC50 = 61000 nM
|
[60] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 14f
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5091; CHEMBL131229
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[22] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[(1S)-1-[3-(cyclohexylmethyl)-1,2,4-oxadiazol-5-yl]-2-(1H-indol-3-yl)ethyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL310193; BDBM50080175
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[60] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-6,6-dimethyl-2-phenyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933737; BDBM50360641
Click to Show/Hide
|
||||
| Activity |
IC50 = 62100 nM
|
[48] | |||
| Compound Name |
2-(4-p-Tolyl-1H-1,2,3-triazol-1-yl)cyclopentanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642288; BDBM50334627
Click to Show/Hide
|
||||
| Activity |
IC50 = 62100 nM
|
[61] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5e
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5096; CHEMBL335628
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[22] | |||
| Compound Name |
4-(4-Methoxyanilino)-5-anilinophthalimide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL8095; SCHEMBL8833729; BDBM50040914; 4-anilino-5-(4-methoxy-anilino)-phthalimide; 5-anilino-6-(4-methoxyanilino)isoindole-1,3-dione; 5-(4-Methoxy-phenylamino)-6-phenylamino-isoindole-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[7] | |||
| Compound Name |
1-[1-(3-Aminophenyl)-3-Tert-Butyl-1h-Pyrazol-5-Yl]-3-Naphthalen-1-Ylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
pyrazolourea, 1b; CHEMBL522387; SCHEMBL12245425; BDBM31825; DB06882; Q27095788; 1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)-3-(4-chlorophenyl)urea, 1c; 1-[2-(3-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl]-3-naphthalen-1-yl-urea
Click to Show/Hide
|
||||
| Activity |
IC50 = 64100 nM
|
[62] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5065; CHEMBL335284
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[22] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-oxo-3-[[(1S)-1-(3-pentyl-1,2,4-oxadiazol-5-yl)propyl]amino]propyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL311370; BDBM50080184
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[60] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-phenyl-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933743; BDBM50360648
Click to Show/Hide
|
||||
| Activity |
IC50 = 65800 nM
|
[48] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5066; CHEMBL334891
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[22] | |||
| Compound Name |
8-(4-Hydroxyanilino)-1-(3-morpholin-4-ylpropyl)-[1,3]oxazolo[4,5-g]quinazolin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2064381; BDBM50389378
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[63] | |||
| Compound Name |
2-(4-p-Tolyl-1H-1,2,3-triazol-1-yl)cycloheptanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642298; BDBM50334630
Click to Show/Hide
|
||||
| Activity |
IC50 = 66100 nM
|
[61] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(4-hydroxyphenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933734; BDBM50360638
Click to Show/Hide
|
||||
| Activity |
IC50 = 66600 nM
|
[48] | |||
| Compound Name |
12-(4-Methoxyphenyl)-3,8-diphenyl-1,3,4,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-2(6),4,9,11-tetraen-7-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3954137; BDBM50206301
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[64] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5070; CHEMBL129842
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[22] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 15c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5106; CHEMBL336958
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[22] | |||
| Compound Name |
3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55394; SCHEMBL6423238; BDBM50128290; 3-[1-[1-(cyclopropylmethyl)piperidin-4-yl]indol-3-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[4] | |||
| Compound Name |
4-[[[3-Acetyl-4-(cyclohexylmethoxy)benzyl]amino]carbonyl]phenylphosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160317
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[65] | |||
| Compound Name |
(2S)-2-[[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2382019
Click to Show/Hide
|
||||
| Activity |
IC50 = 69100 nM
|
[52] | |||
| Compound Name |
(2S,3R)-2-[[(2S)-2-[[(4S)-4-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790805; BDBM50370354
Click to Show/Hide
|
||||
| Activity |
IC50 = 69500 nM
|
[66] | |||
| Compound Name |
N-((5-Bromo-1H-indol-3-yl)(phenyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779747; BDBM50345180
Click to Show/Hide
|
||||
| Activity |
IC50 = 71600 nM
|
[47] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5d
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318300; BDBM5095
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[22] | |||
| Compound Name |
8-Chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-({[1-(1-propylpiperidin-4-yl)-1H-1,2,3-triazol-4-yl]methyl}amino)quinoline-3-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495617; SCHEMBL4959910; BDBM29924; substituted 6-aminoquinoline-3-carbonitrile, 35
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[54] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5f
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL103838; BDBM5097
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[53] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77067; BDBM5092
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[22] | |||
| Compound Name |
1-(4-Methoxyphenyl)-2-(4-m-tolyl-1H-1,2,3-triazol-1-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642271; BDBM50334614
Click to Show/Hide
|
||||
| Activity |
IC50 = 72800 nM
|
[61] | |||
| Compound Name |
[4-[[(3S,6R,9S,12R,15R,22R)-15-Acetamido-6-(2-amino-2-oxoethyl)-2,5,8,11,14,21-hexaoxo-3,9-di(propan-2-yl)-1,4,7,10,13,20-hexazabicyclo[20.3.0]pentacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL359934; BDBM50074705
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[57] | |||
| Compound Name |
7-Amino-3-decyl-4-methylchromen-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3612751; BDBM50116792
Click to Show/Hide
|
||||
| Activity |
IC50 = 73500 nM
|
[67] | |||
| Compound Name |
Caftaric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-WCV7W3174L; WCV7W3174L; cis-caftaric acid; Caffeoyltartaric acid; 2-Caffeoyl-L-tartaric acid; C13H12O9; Caffeoyl tartaric acid; monocaffeoyltartaric acid; Caftaric acid , HPLC Grade; Caftaric acid, >=97.0%; CHEMBL558557; DTXSID3036866; SCHEMBL16426394; Caftaric acid, analytical standard; HY-N0321; ZINC2389524; 9139AF; MFCD02094177; s3308; AKOS022175477; N2169; A12025; 879C587; Q-100761; Q5017207; Caftaric acid, United States Pharmacopeia (USP) Reference Standard; (2R,3R)-2-((E)-3-(3,4-dihydroxyphenyl)acryloyloxy)-3-hydroxysuccinic acid; (2R,3R)-2-{[3-(3,4-Dihydroxyphenyl)prop-2-enoyl]oxy}-3-hydroxybutanedioic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[68] | |||
| Compound Name |
3-(3-Chloro-4-methylphenyl)-6,6-dimethyl-2-pyridin-4-yl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933749; BDBM50360654
Click to Show/Hide
|
||||
| Activity |
IC50 = 74300 nM
|
[48] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 12b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL316967; BDBM5098
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[53] | |||
| Compound Name |
7-(3,5-Dimethyl-1,2-oxazol-4-yl)-N-[4-[2-(1,4-dimethylpiperazin-1-ium-1-yl)ethoxy]phenyl]-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3648042; SCHEMBL13609693; BDBM97844; US8481536, 387
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[69] | |||
| Compound Name |
2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)-1-phenylethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683301; BDBM50337684
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(3S,6S,9R,20S)-6-[(2S)-Butan-2-yl]-3-[(4-hydroxyphenyl)methyl]-2,5,8,11,14-pentaoxo-9-(sulfanylmethyl)-1,4,7,10,15-pentazacycloicosane-20-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791365; BDBM50370732
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[56] | |||
| Compound Name |
1-(2-(4-Decyl-1H-1,2,3-triazol-1-yl)ethyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683295; BDBM50337689
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
1-(2-(4-Butyl-1H-1,2,3-triazol-1-yl)ethyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683292; BDBM50337692
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)-1-(thiophen-2-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683303; BDBM50337682
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
2-[4-[(4-Amino-3-phenylpyrazolo[3,4-d]pyrimidin-1-yl)methyl]triazol-1-yl]-N-(4-chlorophenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683306; BDBM50337679
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
1-(4-(1-(2-(4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-1H-1,2,3-triazol-4-yl)phenyl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683299; BDBM50337686
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
7-(3,5-Dimethyl-1,2-oxazol-4-yl)-N-[4-[2-(1,4-dimethylpiperazin-1-ium-1-yl)ethoxy]phenyl]-5-methyl-1,2,4-benzotriazin-3-amine;2,2,2-trifluoroacetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3956619; SCHEMBL14472144
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[71] | |||
| Compound Name |
2-(6-Amino-9H-purin-9-yl)-1-(pyridin-3-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL501256; BDBM50268239; 2-(6-Amino-9H-purine-9-yl)-1-(pyridine-3-yl)ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[72] | |||
| Compound Name |
1-(2-(4-Heptyl-1H-1,2,3-triazol-1-yl)ethyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683294; BDBM50337690
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
1H-Pyrazolo[3,4-d]pyrimidine-3,4-diamine, N,N'-diphenyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM3006; CHEMBL332333; SCHEMBL8117270; CTK0A5947; ZINC21592; DTXSID70416134; 1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine,n3,n4-diphenyl-; 3-N,4-N-diphenyl-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine; 3,4-diphenylamino-1H-pyrazolo[3,4-d]pyrimidine; 4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 7; 3,4-Di-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidine; N,N'-Diphenyl-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine; 3-N,4-N-diphenyl-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[73] | |||
| Compound Name |
2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)-1-p-tolylethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683302; BDBM50337683
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
2-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)-1-(4-chlorophenyl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1681804; BDBM50337685
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[70] | |||
| Compound Name |
(2S,3R)-2-[[(2S)-2-[[(3S)-3-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790809; BDBM50370353
Click to Show/Hide
|
||||
| Activity |
IC50 = 75400 nM
|
[66] | |||
| Compound Name |
(S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-[4-(3-methyl-butyl)-thiazol-2-yl]-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77068; BDBM50080202
Click to Show/Hide
|
||||
| Activity |
IC50 = 76000 nM
|
[60] | |||
| Compound Name |
(S)-2-((S)-3-{(S)-2-[2-Amino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-carboxy-butyrylamino}-4-carboxy-butyrylamino)-3-methyl-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL431249; BDBM50148024
Click to Show/Hide
|
||||
| Activity |
IC50 = 76300 nM
|
[66] | |||
| Compound Name |
3-Cyclohexyl-6,6-dimethyl-2-thiophen-2-yl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933751; BDBM50360656
Click to Show/Hide
|
||||
| Activity |
IC50 = 77300 nM
|
[48] | |||
| Compound Name |
N-[3-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-isonicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55592; SCHEMBL1430; BDBM50290421; N-[3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]pyridine-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[74] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 13b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5102; CHEMBL407143
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[22] | |||
| Compound Name |
(2S,3R)-2-[[(4S)-4-[[(2S)-2-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790804; BDBM50370349
Click to Show/Hide
|
||||
| Activity |
IC50 = 80700 nM
|
[66] | |||
| Compound Name |
2-(4-(4-Fluoro-3-methylphenyl)-1H-1,2,3-triazol-1-yl)-1-phenylethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642266; BDBM50334609
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[61] | |||
| Compound Name |
[2-[[(1S)-1-[3-[(3,4-Dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]ethyl]carbamoyl]-1H-indol-5-yl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3706656; BDBM50217232
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[53] | |||
| Compound Name |
2-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933074; BDBM50360643
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[48] | |||
| Compound Name |
2-(6-Amino-7H-purine-7-yl)-1-(1H-indole-3-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL485246; BDBM50268224
Click to Show/Hide
|
||||
| Activity |
IC50 = 82000 nM
|
[72] | |||
| Compound Name |
4-(4-Fluorophenyl)-1-(4-nitrophenyl)-3-(pyridin-4-yl)-1H-pyrazol-5-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011295; SCHEMBL16232219; BDBM50379225; 4-(4-Fluorophenyl)-1-(4-nitrophenyl)-3-(pyridin-4-yl)-1H-pyrazol- 5-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 82000 nM
|
[50] | |||
| Compound Name |
2-(4-(4-Fluoro-3-methylphenyl)-1H-1,2,3-triazol-1-yl)-1-p-tolylethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642270; BDBM50334612
Click to Show/Hide
|
||||
| Activity |
IC50 = 82300 nM
|
[61] | |||
| Compound Name |
3-(3-Chloro-4-methylphenyl)-2-(3-methoxyphenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933747; BDBM50360652
Click to Show/Hide
|
||||
| Activity |
IC50 = 82700 nM
|
[48] | |||
| Compound Name |
3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1H-indol-3-yl]-pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52654; BDBM50128282; 3-[1-(1-Methyl-4-piperidinyl)-1H-indole-3-yl]-4-(1H-indole-3-yl)-3-pyrroline-2,5-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[4] | |||
| Compound Name |
(R)-4-{(S)-2-[2-Amino-3-(4-phosphonooxy-phenyl)-propionylamino]-2-carboxy-acetylamino}-5-((S)-1-carboxy-2-methyl-propylcarbamoyl)-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL106664; BDBM50148020
Click to Show/Hide
|
||||
| Activity |
IC50 = 83200 nM
|
[66] | |||
| Compound Name |
2-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933729; BDBM50360633
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[48] | |||
| Compound Name |
(E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-(2-fluoro-5-(trifluoromethyl)phenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551838; BDBM50294003
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[51] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 14d
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5089; CHEMBL131944
Click to Show/Hide
|
||||
| Activity |
IC50 = 87000 nM
|
[22] | |||
| Compound Name |
{(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl]-1-[5-(3-cyclohexyl-propyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL430262; BDBM50103044
Click to Show/Hide
|
||||
| Activity |
IC50 = 87000 nM
|
[75] | |||
| Compound Name |
N-((4-Chlorophenyl)(5-methoxy-1H-indol-3-yl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779752; BDBM50345185; N-Phenyl-N-methyl-alpha-(4-chlorophenyl)-5-methoxy-1H-indole-3-methaneamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 87000 nM
|
[47] | |||
| Compound Name |
[4-[[(3S,6R,9S,12R,15R,22R)-6-(2-Amino-2-oxoethyl)-15-(ethanethioylamino)-2,5,8,11,14,21-hexaoxo-3,9-di(propan-2-yl)-1,4,7,10,13,20-hexazabicyclo[20.3.0]pentacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL366543; BDBM50074706
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[57] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[(1S)-2-(1H-indol-3-yl)-1-[3-(4-methylpentyl)-1,2,4-oxadiazol-5-yl]ethyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL405008; BDBM50080203
Click to Show/Hide
|
||||
| Activity |
IC50 = 89000 nM
|
[60] | |||
| Compound Name |
(18S)-18-(Aminomethyl)-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL316239; BDBM50052037
Click to Show/Hide
|
||||
| Activity |
IC50 = 89000 nM
|
[6] | |||
| Compound Name |
3-(4-(2-(4-Phenyl-1H-1,2,3-triazol-1-yl)acetyl)phenyl)-2H-chromen-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642280; BDBM50334619
Click to Show/Hide
|
||||
| Activity |
IC50 = 89500 nM
|
[61] | |||
| Compound Name |
6-(2-Morpholinoethylamino)-4-(4-phenoxyphenylamino)-1,7-naphthyridine-3-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL371095; SCHEMBL4773967; BDBM50173837; 6-(2-morpholin-4-ylethylamino)-4-(4-phenoxyanilino)-1,7-naphthyridine-3-carbonitrile; 6-[(2-morpholin-4-ylethyl)amino]-4-[(4-phenoxyphenyl)amino]-[1,7]naphthyridine-3-carbonitrile; 6-[(2-morpholin-4-ylethyl)amino]-4-[(4-phenoxyphenyl)amino]-1,7-naphthyridine-3-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[76] | |||
| Compound Name |
Methyl 3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL56671; SCHEMBL1927119; BDBM50290418; 3-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[74] | |||
| Compound Name |
N-[3-[(4-Pyridin-3-ylpyrimidin-2-yl)amino]phenyl]pyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292866; SCHEMBL1442; BDBM50290428; Pyridine-2-carboxylic acid [3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[74] | |||
| Compound Name |
(2R)-2-[[(2S,3S)-4-[(E)-3-[(1R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]-hydroxymethoxy]-3-(3,4-dihydroxyphenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL541265
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[68] | |||
| Compound Name |
(2S,3R)-2-[[(3S)-3-[[(2S)-2-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-3-carboxypropanoyl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790815; BDBM50370344
Click to Show/Hide
|
||||
| Activity |
IC50 = 90700 nM
|
[66] | |||
| Compound Name |
(E)-N-(4-Methyl-3-(2-(6-(cyclopropylamino)-9H-purin-9-yl)vinyl)-phenyl)-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL564575; SCHEMBL10277503; SCHEMBL10277508; BDBM50293994; N-[3-[(E)-2-[6-(cyclopropylamino)purin-9-yl]ethenyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[51] | |||
| Compound Name |
(S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-(3-benzyl-[1,2,4]oxadiazol-5-yl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL311135; BDBM50080190
Click to Show/Hide
|
||||
| Activity |
IC50 = 92000 nM
|
[60] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 10
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5080; CHEMBL334539
Click to Show/Hide
|
||||
| Activity |
IC50 = 92000 nM
|
[22] | |||
| Compound Name |
(3-Nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL56081; SCHEMBL1977; 2-Pyrimidinamine,N-(3-nitrophenyl)-4-(3-pyridinyl)-; BDBM50290423; VCC117886; N-(3-nitrophenyl)-4-pyridin-3-ylpyrimidin-2-amine; 4-(3-Pyridinyl)-N-(3-nitrophenyl)pyrimidin-2-amine; N-(3-nitrophenyl)-4-(3-pyridyl)-2-pyrimidine-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[74] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-aminohexanoyl]amino]-3-(4-aminophenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791367; BDBM50370736
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[56] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(4-methoxyphenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933736; BDBM50360640
Click to Show/Hide
|
||||
| Activity |
IC50 = 94100 nM
|
[48] | |||
| Compound Name |
(2R,3S,4R,5S)-2-(Hydroxymethyl)-5-(3-methoxyphenoxy)oxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205390; BDBM50401865
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[77] | |||
| Compound Name |
((S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl]-1-{2-(4-methoxy-phenyl)-5-[(2-methoxy-phenylcarbamoyl)-methyl]-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306146; BDBM50103058
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[75] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 13a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5101; CHEMBL337253
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[22] | |||
| Compound Name |
2-Fluoro-N'-[2-(1H-indol-3-yl)-2-oxoacetyl]benzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1796184; BDBM50346831
Click to Show/Hide
|
||||
| Activity |
IC50 = 96000 nM
|
[78] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5058; CHEMBL130871
Click to Show/Hide
|
||||
| Activity |
IC50 = 96000 nM
|
[22] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 11
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5081; CHEMBL134042
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[22] | |||
| Compound Name |
N-((4-Chlorophenyl)(1-methyl-1H-indol-3-yl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779744; BDBM50345177
Click to Show/Hide
|
||||
| Activity |
IC50 = 98300 nM
|
[47] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 12c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5099; CHEMBL336314
Click to Show/Hide
|
||||
| Activity |
IC50 = 99000 nM
|
[22] | |||
| Compound Name |
4-[5-Amino-4-(4-fluorophenyl)-3-pyridin-4-ylpyrazol-1-yl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011297; SCHEMBL14839292; BDBM50379224; 4-[5-Amino-4-(4-fluorophenyl)-3-(pyridin-4-yl)-1H- pyrazol-1-yl]benzonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
3-[1-(1-Benzyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL300549; BDBM50128284; 3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione; 3-(1-Methyl-1H-indole-3-yl)-4-[1-(1-benzylpiperidine-4-yl)-1H-indole-3-yl]-1H-pyrrole-2,5-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
(S)-4-[(S)-2-((2S,3S)-2-Amino-3-methyl-pentanoylamino)-4-carboxy-butyrylamino]-4-[(S)-1-carboxy-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL194835; BDBM50174136
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[79] | |||
| Compound Name |
Ethyl 1-[3-oxo-3-(4-phenylmethoxyphenyl)propyl]piperidine-4-carboxylate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL542891
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-m-tolyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307062; SCHEMBL2460990; BDBM50051300
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
(3-Bromo-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL72393; SCHEMBL2459255; BDBM50051306; N-(3-Bromophenyl)-5,6,7,8-tetrahydro-9H-pyrimido[4,5-b]indol-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-N-(2,5-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4264052; CHEMBL3648021; BDBM97822; ZINC96167699; US8481536, 351
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
(8S,16S)-3,16-Dihydroxy-9,10-seco-1,3,5(10)-cholestatrien-9-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456294; Calicoferol I; USFQLAVWHQCNDG-AYEIPMSGSA-; BDBM50358248; LMST03020180
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10p
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4031; CHEMBL303127; N,N'-Diphenyl[2,2'-dithiobis(6-chloro-1-methyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
[4-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-propyl)-methyl-carbamoyl]-propylcarbamoyl}-ethyl)-phenyl]-phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL58421; BDBM50289745
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[82] | |||
| Compound Name |
1-(4-Phenylmethoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL545006; DTXSID80669831; NSC25590; NSC-25590; 1-[4-(Benzyloxy)phenyl]-3-(piperidin-1-yl)propan-1-one--hydrogen chloride (1/1)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[1-(4-Methylpiperazin-1-yl)-3-phenylpropan-2-yl] N-(3-bromophenyl)-N-[6-methylsulfanyl-1-(2-phenylpropyl)pyrazolo[3,4-d]pyrimidin-4-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4060917
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[83] | |||
| Compound Name |
N-[[(18S)-3,5-Dioxo-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaen-18-yl]methyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315389; BDBM50052036
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
5-Pyridin-4-yl-2-(2,4,6-trichlorophenyl)pyrazol-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011303; SCHEMBL14839420; BDBM50379219
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
Phenyl-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433305; SCHEMBL2461588; BDBM50051310
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
5-[(1E)-2-(5,6-Dibromo-2-hydroxy-3-methoxyphenyl)-1-azavinyl]-3-hydrobenzimida zol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335244; Oprea1_441164; Oprea1_611703; ZINC3148634; BDBM50026039; AKOS024352751; MCULE-4354812735; ST50978263
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[84] | |||
| Compound Name |
4,5-Bis[phenyl(methyl)amino]phthalimide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL267941; SCHEMBL8834735; BDBM50040918; 4,5-Bis(N-methyl-N-phenylamino)phthalimide; 5,6-bis(N-methylanilino)isoindole-1,3-dione; 5,6-Bis-(methyl-phenyl-amino)-isoindole-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
2-[(Dimethylamino)methyl]-3-(3,4-dimethylphenyl)sulfanyl-1-(4-phenylmethoxyphenyl)propan-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL538507
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
4-Methyl-N-[3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL59036; SCHEMBL9763; BDBM50290430; VCC783678; 4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
4-Phenyl-1H-1,2,3-triazole-1-acetic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642285; 4-phenyl-1-(2-methoxyethan-2-on-1-yl)-1H-1,2,3-triazole; BDBM50334624; methyl 2-(4-phenyl-1H-1,2,3-triazol-1-yl)acetate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
[4-[[(3R,6S,9R,12S,23S)-6-(2-Amino-2-oxoethyl)-2,5,8,11,14,22-hexaoxo-3,9-di(propan-2-yl)-15-oxa-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL435738; BDBM50074704
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[57] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10q
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64459; BDBM4032; N,N'-Diphenyl[2,2'-dithiobis(1,6-dimethyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[16] | |||
| Compound Name |
{(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl]-1-[5-(3-cyclohexyl-propyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL65844; BDBM50103049
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[75] | |||
| Compound Name |
(3-Nitro-phenyl)-(4-pyridin-2-yl-pyrimidin-2-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60816; SCHEMBL1886; BDBM50290424; N-(3-nitrophenyl)-4-pyridin-2-ylpyrimidin-2-amine; 4-(2-Pyridinyl)-N-(3-nitrophenyl)pyrimidin-2-amine; N-(3-nitrophenyl)-4-(2-pyridyl)-2-pyrimidine-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
N-[4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CGP-53716; CGP53716;CGP 53716; CHEMBL20926; cgp53716; SCHEMBL9782; BCP34642; BDBM50240407; MFCD00945675; VCC347042; AK688902; BS-15548; N-(4-Methyl-3(4-(pyridine-3-yl)pyrimidin-2-ylamino)phenyl)benzamide; N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide; N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
2-[(Dimethylamino)methyl]-1-(4-phenylmethoxyphenyl)prop-2-en-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL552859
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[[2-[(Dimethylamino)methyl]-3-oxo-3-(4-phenylmethoxyphenyl)propyl]amino]urea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL541307
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
4-[4-(2-Dimethylaminomethyl-acryloyl)-phenoxysulfonyl]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL80030; BDBM50031651; 4-[[4-[2-Methylene-3-(dimethylamino)propionyl]phenoxy]sulfonyl]benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4018; CHEMBL292287; N,N'-Diphenyl[2,2'-dithiobis(1,4-dimethyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
1-Isopropyl-3-(2-methylquinolin-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1241682
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[27] | |||
| Compound Name |
N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL423288; SCHEMBL19556857; BDBM50240406; N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
4-Pyridin-4-yl-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55662; SCHEMBL1269; BDBM50290420; 4-(4-Pyridinyl)-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine; N-[3-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-4(4-pyridyl)-2-pyrimidineamine; N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-4-(4-pyridyl)-2-pyrimidine-amine; (4-Pyridin-4-yl-pyrimidin-2-yl)-[3-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
(2S,3S)-2-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-1-oxo-propylamino]-4-carboxy-1-oxo-butylamino}-4-carboxy-1-oxo-butylamino)-3-methyl-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL199202; BDBM50174135
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[79] | |||
| Compound Name |
2-Thioxo-1H-indole-3-carboxamide deriv. 13
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64781; BDBM4047; l-Methyl-N-phenyl-2-(phenyldithio)-1H-indole-3-carboxamide; 1-Methyl-2-(phenyldithio)-N-phenyl-1H-indole-3-carboxamide; 1-methyl-N-phenyl-2-(phenyldisulfanyl)-1H-indole-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL20252; SCHEMBL9837; BDBM50287091; VCC051689; Naphthalene-2-carboxylic acid [4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10d
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4019; CHEMBL294205; N,N'-Diphenyl[2,2'-dithiobis(4-methoxy-1-methyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Ethyl 5-amino-3-pyridin-4-yl-1-(2,4,6-trichlorophenyl)pyrazole-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011300; SCHEMBL14833707; BDBM50379221; Ethyl 5-amino-3-(pyridin-4-yl)-1-(2,4,6-trichlorophenyl)-1H-pyrazole-4-carb-oxylate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
5-[(1E)-2-(5,6-Dibromo-3-ethoxy-2-hydroxyphenyl)-1-azavinyl]-3-hydrobenzimidaz ol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335245; Oprea1_030343; Oprea1_495189; ZINC868331; BDBM50026038; AKOS024361565; MCULE-8743433907; ST50992035
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[84] | |||
| Compound Name |
(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-(3-fluoro-phenyl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL308582; SCHEMBL2460989; BDBM50051307; N-(3-fluorophenyl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
2-Cyano-2-(3,4-dihydroxy-benzyl)-thioacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78249; TRYPHOSTIN; BDBM50031654
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[4-[[(3R,6S,9R,12S,23S)-6-(2-Amino-2-oxoethyl)-2,5,8,11,14,22-hexaoxo-3,9-di(propan-2-yl)-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL177372; BDBM50074712
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[57] | |||
| Compound Name |
(2S,3R)-2-[[(4S)-4-[[(2S)-2-[[(2S)-2-Amino-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790813; BDBM50370345
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
Di(3-phenyl-1H-2-indolyl) disulfide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL422540; BDBM50036005; Bis(3-phenyl-1H-indole-2-yl) persulfide; 3-phenyl-2-[(3-phenyl-1H-indol-2-yl)disulfanyl]-1H-indole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
2-Propen-1-one, 2-((dimethylamino)methyl)-1-phenyl-, hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CCRIS 8957; CHEMBL468975; 1-Phenyl-2-dimethylaminomethyl-2-propen-1-one hydrochloride; 2-((Dimethylamino)methyl)-1-phenyl-2-propen-1-one hydrochloride; SCHEMBL4799828; DTXSID50143416; NSC382011; NSC-382011; 2-((DIMETHYLAMINO)METHYL)-1-PHENYL-2-PROPEN-1-ONE HYDROCLORIDE
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
N-(4-Butylphenyl)-7-(3,5-dimethoxyphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4273523; CHEMBL3648023; BDBM97824; ZINC96167701; US8481536, 353
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ro-31-8425; Ro31.8425; ACMC-20ckvd; BDBM2700; CHEMBL421565; SCHEMBL4360666; CTK4B7562; DTXSID60927365; BCP27621; HSCI1_000343; BIM 10; Bisindolylmaleimide X, HCl; ES-0009; NCGC00262061-02; K00205; Ro-31-8425 - CAS 131848-97-0
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[85] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-N-(4-ethoxyphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4266605; CHEMBL3648024; BDBM97825; ZINC96167702; US8481536, 354
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
2-Methoxy-N-[3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL299707; SCHEMBL9338; BDBM50290429; VCC092935; 2-Methoxy-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide; 2-Methoxy-N-[3-[[4-(3-pyridinyl)pyrimidin-2-yl]amino]phenyl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10i
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60200; BDBM4024; N,N'-Diphenyl[2,2'-dithiobis(1,5-dimethyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-N-(3,4-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4271489; CHEMBL3648022; BDBM97823; ZINC96167700; US8481536, 352
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
6-methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine; 2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine; JR9RZF7KDS; UNII-JR9RZF7KDS; CHEMBL278103; 4-methyl-3-N-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine; 1,3-Benzenediamine, 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-; N-(5-Amino-o-tolyl)-4-(3-pyridyl)-2-pyrimidinamine; N-(5-Amino-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidineamine; 4-Methyl-N3-[4-(3-Pyridinyl)-2-Pyrimidinyl]-1,3-Benzenediamine; 4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline; 1,3-Benzenediamine, 4-methyl-N3-(4-(3-pyridinyl)-2-pyrimidinyl)-; 4-Methyl-N*3*-(4-pyridin-3-yl-pyrimidin-2-yl)-benzene-1,3-diamine; N-(5-Amino-2-methylphenyl)-4-(3-pridyl)-2-pyrimidineamine; Imatinib amine; 4-Methyl-N3-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine; 4-Methyl-N3-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine; 6-METHYL-N1-[4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL]BENZENE-1,3-DIAMINE; zlchem 1354; Imatinib amine [USP]; PubChem18212; Imatinib EP Impurity F; ACMC-209d7r; SCHEMBL2392; KSC174K2P; BEN021; CTK0H4527; DTXSID30433443; ZLE0132; Imatinib related compound F [USP]; ACT04895; BCP22918; AC-619; ANW-21397; BDBM50287097; CA0157; MFCD09028125; VCC489937; ZINC21985310; AKOS015888614; AC-2147; ACN-026829; CCG-310976; CS-W014568; DS-0284; LS41060; MCULE-2150821496; QC-1118; 112GI007; AK-23922; AT-20154; BR-23922; SC-19340; AB0005260; A3351; AM20050827; FT-0647597; FT-0655675; FT-0696298; VU0549314-1; M-1404; 460A101; Q-100177; N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimid; F9995-0188; 3-[[4-(3-Pyridinyl)pyrimidine-2-yl]amino]-4-methylaniline; n-(2-methyl-5-aminophenyl)-4-(3-pyridyl)-2-pyrimidine amine; N-(5-Amino-2-methyl phenyl)-4-(3-pyridyl)-2-pyrimidineamine; N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2- pyrimidineamine; N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine amine; N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine; 1,3-Benzenediamine, 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl; 4-Methyl-N-3-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine; 4-methyl-N~3~-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine; 4-Methyl-N3-(4-pyridin-3-yl-pyrimidin-2-yl)-benzene-1,3-diamine; 4-methyl-N3-[4-(3-piridinyl)-2-pirimidinyl]-1,3-benzendiamine; 4-Methyl-N3-[4-(3-pyridyl)-2-pyrimidinyl]-1,3-phenylenediamine; 6-Methyl-N-(4-(pyridine-3-yl)pyrimidin-2-yl)benzene-1,3-diamine; 6-Methyl-N1-(4-(pyridine-3-yl)pyrimidin-2-yl)benzene-1,2-diamine; N-(5-amino-2-methyl phenyl)-4-(3-pyridinyl)2-pyrimidine-amine; N-(5-amino-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidine-amine; 4-Methyl-N~3~-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
4,5-Bis[4-(diethylamino)anilino]phthalimide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL8223; BDBM50040921; 5,6-Bis-(4-diethylamino-phenylamino)-isoindole-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-(2-Methyl-5-nitrophenyl)-4-pyridin-3-ylpyrimidin-2-amine; N-(2-Methyl-5-nitrophenyl)-4-(3-pyridyl)-2-pyrimidine-amine; n-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-pyrimidineamine; CHEMBL20426; 2-Pyrimidinamine, N-(2-methyl-5-nitrophenyl)-4-(3-pyridinyl)-; (2-Methyl-4-nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amine; MFCD02179269; N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-pyrimidinamine; 2-Pyrimidinamine,N-(2-methyl-5-nitrophenyl)-4-(3-pyridinyl)-; 2-Methyl-5-nitro-N-[4-(pyridin-3-yl)pyrimidin-2-yl]benzenamine; SCHEMBL1550; ACMC-1C66W; KSC527I5D; N-(2-methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimid; PYR402; SCHEMBL13597737; CTK4C7451; DTXSID50443544; ACT04899; BCP12559; N-(2-methyl-5-nitro-phenyl)-4-pyridin-3-yl-pyrimidin-2-amine; ANW-41942; BDBM50287093; VCC987289; ZINC21298122; AKOS015909809; AC-2148; ACN-026830; MCULE-9226886591; QC-1117; 112GI008; AK-47893; DS-14539; SC-47708; AB0005259; AM20050826; FT-0654432; M2584; X2637; VU0549313-1; M-8440; 460M098; A809314; J-008922; 2-(2-methyl-5-nitroanilino)-4-(3-pyridinyl)pyrimidine; F9995-0184; N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-pyrimidine-amine; N-(2-methyl-5-nitrophenyl)-4-(3-pyridinyl)-2-pyrimidinamine; N-(2-Methyl-5-nitrophenyl)-4-(3-pyridyl)-2-pyrimidinylamine; N-(5-nitro-2-methylphenyl)-4-(3-pyridinyl)-2-pyrimidineamine; (2-Methyl-5-nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amine; N-(2-Methyl-5-nitrophenyl)-4- (pyridin-3-yl)pyrimidin-2-amine; N-(2-methyl-5-nitrophenyl)-4-(3-pyridinyl)-2 pyrimidine amine; N-(2-methyl-5-nitrophenyl)-4-(3-pyridinyl)-2-pyrimidine amine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[86] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-N-(2,4-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4271461; CHEMBL3648020; BDBM97821; ZINC96167698; US8481536, 350
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
4-Phenyl-1-(4-phenyl-1H-1,2,3-triazol-1-yl)but-3-en-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642267; BDBM50334610
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
2-(Morpholin-4-ylmethyl)-1-(4-phenylmethoxyphenyl)prop-2-en-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL544067
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(2S,3R)-2-[[(3S)-3-[[(2S)-2-[[(2S)-2-Amino-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-3-carboxypropanoyl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790816; BDBM50370350
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
6-(4-Amino-1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)quinolin-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1241864
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[27] | |||
| Compound Name |
[4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL57581; SCHEMBL8837820; BDBM50290425; 4-(4-chlorophenyl)-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine; N-[3-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-4-(4-chloro-phenyl)-2-pyrimidineamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
2-Thioxo-1H-indole-3-carboxamide deriv. 14
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64231; BDBM4048; 2-(benzyldisulfanyl)-1-methyl-N-phenyl-1H-indole-3-carboxamide; 2-(Benzyldithio)-1-methyl-N-phenyl-1H-indole-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-N-(2,3-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4273892; CHEMBL3639468; BDBM97827; ZINC96167704; US8481536, 356
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
2-(4-Methylpiperazin-1-yl)ethyl N-(3-bromophenyl)-N-[6-methylsulfanyl-1-(2-phenylpropyl)pyrazolo[3,4-d]pyrimidin-4-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2407628; SCHEMBL20356842
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[83] | |||
| Compound Name |
(2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-carboxy-butyrylamino]-4-carboxy-1-oxo-butylamino}-3-methyl-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL197909; BDBM50174134
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[79] | |||
| Compound Name |
Calicoferol C
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515982; BDBM50358249
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
1-(4-Phenylmethoxyphenyl)-2-(piperazin-1-ylmethyl)prop-2-en-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL544538
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Bisindolylmaleimide xi, HCl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ro-32-0432; Ro 31-0432, solid; C28H28N4O2 HCl; SCHEMBL9388239; CHEMBL1202927; CTK8E8395; J-008802
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[85] | |||
| Compound Name |
N-((5-Methoxy-1H-indol-3-yl)(4-methoxyphenyl)methyl)-Nmethylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779748; BDBM50345181
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[47] | |||
| Compound Name |
2,2-Dihydroxy-3-oxo-3-phenylpropionic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL45149; BDBM50101080; DB-119338; 2,2-Dihydroxy-3-oxo-3-phenyl-propionic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[87] | |||
| Compound Name |
4-Cyano-N-[3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL58580; SCHEMBL9642; BDBM50290411; VCC015466; 4-Cyano-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide; 4-Cyano-N-[3-[[4-(3-pyridinyl)pyrimidin-2-yl]amino]phenyl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
[4-[[(3R,6S,9R,12S,18R)-6-(2-Amino-2-oxoethyl)-2,5,8,11,14,17-hexaoxo-3,9-di(propan-2-yl)-1,4,7,10,13,16-hexazabicyclo[16.3.0]henicosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL174819; BDBM50074707
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[57] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-5-methyl-N-pyridin-4-yl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4269215; CHEMBL3648025; BDBM97826; ZINC96167703; US8481536, 355
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
Calicoferol B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL464351; BDBM50358250
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
N-Phenyl-4-(pyridin-3-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL57690; N-phenyl-4-pyridin-3-ylpyrimidin-2-amine; SCHEMBL6262145; BDBM50045424; STL122121; ZINC29559018; AKOS005738153; MCULE-6845987679; 4-(3-Pyridinyl)-N-phenylpyrimidin-2-amine; Phenyl-(4-pyridin-3-yl-pyrimidin-2-yl)-amine; N-phenyl-N-[4-(3-pyridyl)-2-pyrimidinyl]amine; Phenyl-(4-pyridin-3-yl-pyrimidin-2-yl)-amine sulphate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
2-(2-Aminoethylsulfanylmethyl)-3-(dimethylamino)-1-(4-phenylmethoxyphenyl)propan-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL543361
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10g
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL293889; BDBM4022; N,N'-Diphenyl[2,2'-dithiobis(5-chloro-1-methyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10j
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4025; CHEMBL294341; N,N'-Diphenyl[2,2'-dithiobis(5-methoxy-1-methyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-(3-Chlorophenyl)-9H-pyrimido[4,5-b]indol-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306315; SCHEMBL7497652; ZINC3815156; BDBM50051308; (3-Chloro-phenyl)-(9H-pyrimido[4,5-b]indol-4-yl)-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
(2S,3R)-2-[[(2S)-2-[[(3S)-3-[[(2S)-2-Amino-3-(4-phosphonooxyphenyl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790817; BDBM50370342
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-N-(4-methoxyphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4273687; CHEMBL3648027; BDBM97829; ZINC96167706; US8481536, 358
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
4-Chloro-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL21162; SCHEMBL9677; BDBM50287090; VCC374125; 4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
1-Propanone, 3-(4-morpholinyl)-1-(4-(phenylmethoxy)phenyl)-, hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL542893; 3-(4-Morpholinyl)-1-(4-(phenylmethoxy)phenyl)-1-propanone hydrochloride; DTXSID20199344; MCULE-5918920246
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
BrC=1C=C(C=CC=1)N(C(OCCN1CCN(CC1)C)=O)C1=C2C(=NC(=N1)SCCN1CCOCC1)N(N=C2)CC(C1=CC=CC=C1)Cl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4087882; SCHEMBL17725976
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[83] | |||
| Compound Name |
(S)-4-[(S)-2-((1S,4S)-2-Amino-3-methyl-pentanoylamino)-4-carboxy-1-oxo-butylamino]-4-((S)-1-carboxy-2-phenyl-ethylcarbamoyl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL199107; BDBM50174138
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[79] | |||
| Compound Name |
7-(2-Chlorophenyl)-5-methyl-N-phenyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4266478; CHEMBL3648014; BDBM97815; ZINC35930503; US8481536, 339
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
4-(3-Chlorophenylamino)-5,6-dimethyl-7H-pyrrolo(2,3-d)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CGP-59326; UNII-YP9UZR062O; YP9UZR062O; CHEMBL306081; N-(3-chlorophenyl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 1H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-; 4-(3-chlorophenylamino)-5,6-dimethyl-7h-pyrrolo[2,3-d]pyrimidine; TRX-13; 1H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-; SCHEMBL2463632; CTK0E4305; DTXSID30169619; 4-(m-chloroanilino)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine; BDBM50051317; 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-; Q27294641; (3-Chloro-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
Src SH2 inhibitor, 4
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160323; BDBM93195; 4-[[[4-(Cyclohexylmethoxy)benzyl]amino]carbonyl]phenylphosphate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[65] | |||
| Compound Name |
3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL7339; BDBM50074741; 5-Hydroxy-7-methoxy-3-(3-chlorophenyl)-4H-1-benzopyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Benzyl-N-methyl-4-(phenylsulfamoyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355482; BDBM50043416; ZINC17334508; AKOS008571954; Z31474376
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-5-methyl-N-(3-methylphenyl)-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4265043; CHEMBL3648018; BDBM97819; ZINC96167696; US8481536, 348
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
1 H-Indole-3-alkanamide deriv. 10m
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4004; CHEMBL154822; 2,2 -Dithiobis[N-[[3-hydroxy-4-(methoxycarbonyl)phenyl]methyl]-1H-indole-3-propanamide]; 2,2'-Dithiobis[N-(3-hydroxy-4-methoxycarbonylbenzyl)-1H-indole-3-propanamide]
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[49] | |||
| Compound Name |
N-(3-Bromophenyl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL74722; SCHEMBL2461158; CTK0E4304; DTXSID20442569; BDBM50051312; (3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine; 1H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-(3-bromophenyl)-5,6-dimethyl-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
3-[1-(1-Methyl-piperidin-4-yl)-indol-3-yl]-4-(1-methyl-indol-3-yl)-1H-pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL53596; SCHEMBL3146547; BDBM50128287; 3-(1-methylindol-3-yl)-4-[1-(1-methylpiperidin-4-yl)indol-3-yl]pyrrole-2,5-dione; 3-[1-(1-Methyl-piperidin-4-yl)-indol-3-yl]-4-(1methyl-indol-3-yl)-1H-pyrrole-2,5-dione; 3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1H-indol-3-yl]-pyrrole-2,5-dione; 3-(1-Methyl-1H-indole-3-yl)-4-[1-(1-methylpiperidine-4-yl)-1H-indole-3-yl]-1H-pyrrole-2,5-dione; 3-[1-(1-methyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10u
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4036; CHEMBL291667
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
1-Ethyl-2-[[1-ethyl-3-(phenylcarbamoyl)indol-2-yl]disulfanyl]-N-phenylindole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL156020; BDBM50035994; 3N-phenyl-1-ethyl-2-(1-ethyl-3-phenylcarbamoyl-1H-2-indolyldisulfanyl)-1H-3-indolecarboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
3-(4-Ethoxy-3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1242471; SCHEMBL16665685
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[27] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-5-methyl-N-(4-methylphenyl)-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4275200; CHEMBL3648019; BDBM97820; ZINC96167697; US8481536, 349
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
1-Phenacyl-4-phenyl-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1276040; SCHEMBL15863726; BDBM50334607; 1-phenyl-2-(4-phenyltriazol-1-yl)ethanone; Phenyl-2-(4-phenyl-1,2,3 triazol-1-yl)ethanone; 1-Phenyl-2-(4-phenyl-[1,2,3]triazol-1-yl)-ethanone; 1-phenyl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)ethanone; 4-phenyl-1-(2-phenylethan-2-on-1-yl)-1,2,3-triazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
(3-Chloro-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75177; SCHEMBL2461340; BDBM50051297; N-(3-Chlorophenyl)-5,6,7,8-tetrahydro-9H-pyrimido[4,5-b]indol-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
5-[4-Amino-1-(2,2-dimethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3800138
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-m-tolyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307026; SCHEMBL2459209; BDBM50051304; 5,6-dimethyl-N-(3-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10h
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4023; CHEMBL293251; SCHEMBL8998858; N,N'-Diphenyl[2,2'-dithiobis(5-bromo-1-methyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[16] | |||
| Compound Name |
(3-Nitro-phenyl)-(4-pyridin-4-yl-pyrimidin-2-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55683; SCHEMBL1144; BDBM50290426; VCC792768; N-(3-nitrophenyl)-4-pyridin-4-ylpyrimidin-2-amine; 4-(4-Pyridinyl)-N-(3-nitrophenyl)pyrimidin-2-amine; N-(3-nitrophenyl)-4-(4-pyridyl)-2-pyrimidine-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
N-(3-Chlorophenyl)-5-methyl-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL311129; SCHEMBL2462441; BDBM50051302; (3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
N-(3,4-Dichlorophenyl)-7-(2,6-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4278768; CHEMBL3648017; BDBM97818; US8481536, 347
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM4017; CHEMBL293986; N,N'-Diphenyl[2,2'-dithiobis(4-chloro-1-methyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(3-Chloro-phenyl)-(5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307209; SCHEMBL2462851; CTK0E4303; DTXSID80443592; BDBM50051305; 1H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-diphenyl-; N-(3-chlorophenyl)-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; N-(3-Chlorophenyl)-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidine-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
(S)-4-[(S)-2-((2S,3S)-2-Amino-3-methyl-pentanoylamino)-4-carboxy-butyrylamino]-4-[(S)-1-carboxy-2-(4-phosphonooxy-phenyl)-ethylcarbamoyl]-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373179; BDBM50174137
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[79] | |||
| Compound Name |
Diguanosine tetraphosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
GppppG; bis(guanylyl) diphosphate; (ppG)2; P1,P4-Bis(5'-guanosyl) tetraphosphate; Bis(5'-guanosyl) tetraphosphate; P(1),P(4)-bis(5'-guanosyl) tetraphosphate; CHEMBL448348; G(5')p4(5')G; guanosine(5')tetraphospho(5')guanosine; P1,P4-Di(guanosine-5') tetraphosphate ammonium salt; SCHEMBL851357; BDBM50292505; G(5'')p4(5'')G; guanosine(5'')tetraphospho(5'')guanosine; C01261; P(1),P(4)-bis(5''-guanosyl) tetraphosphate; J-000790; Q27098279; P(1),P(4)-bis(5''-guanosyl) tetrahydrogen tetraphosphate; P(1),P(4)-bis(5'-guanosyl) tetrahydrogen tetraphosphate; Guanosine 5'-(pentahydrogen tetraphosphate), P'''-5'-ester with guanosine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
5-[4-Amino-1-(1,3-dioxolan-2-ylmethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3797590
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
4-Methyl-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL20867; SCHEMBL9820; BDBM50175491; VCC643561; 4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
1-(4-Phenylmethoxyphenyl)-2-(piperidin-1-ylmethyl)prop-2-en-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL544074
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
1-Propanone, 3-(dimethylamino)-1-(4-(phenylmethoxy)phenyl)-, hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL544770; 3-(Dimethylamino)-1-(4-(phenylmethoxy)phenyl)-1-propanone hydrochloride; DTXSID60199343
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
7-(3,5-Dimethoxyphenyl)-N-(2-methoxyphenyl)-5-methyl-1,2,4-benzotriazin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4278717; CHEMBL3648026; BDBM97828; ZINC96167705; US8481536, 357
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[69] | |||
| Compound Name |
1-(4-Bromophenyl)-2-(4-(4-(4-chlorobutyl)phenyl)-1H-1,2,3-triazol-1-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642279; BDBM50334618
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
N-[4-Methyl-3-(4-thiophen-2-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL21078; BDBM50287087
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[86] | |||
| Compound Name |
Methyl 2-[2-[(dimethylamino)methyl]-3-oxo-3-(4-phenylmethoxyphenyl)propyl]sulfanylbenzoate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL538757
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Dithiobis(1H-indole-3-carboxamide) deriv. 10v
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64165; BDBM4037; N,N'-Diphenyl[2,2'-dithiobis(1,7-dimethyl-1H-indole-3-carboxamide)]
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(2-Formyloxymethyl-4-methyl-phenyl)-malonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77070; BDBM50113765
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[91] | |||
| Compound Name |
Chembl4276946
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
GTPL9965; compound 3a [Pipionne et al, 2018]; 1-[5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl]ethan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
5-Chloro-1-methyl-N-phenyl-2-sulfanylidene-3H-indole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-thioxo-1H-indole-3-carboxamide deriv. 9g; CHEMBL62067; BDBM4043; 2,3-Dihydro-5-chloro-1-methyl-2-thioxo-N-phenyl-1H-indole-3-carboxamide; 5-chloro-1-methyl-N-phenyl-2-sulfanylidene-2,3-dihydro-1H-indole-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(18S)-18-[(Benzylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328229; BDBM50052040
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
[4-[[(3R,6S,9R,12S,18S)-6-(2-Amino-2-oxoethyl)-2,5,8,11,14,17-hexaoxo-3,9-di(propan-2-yl)-1,4,7,10,13,16-hexazabicyclo[16.3.0]henicosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL172299; BDBM50074703
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[57] | |||
| Compound Name |
4-Fluoro-N-[3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418279; SCHEMBL9565; BDBM50290412; 4-Fluoro-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
(3-Chloro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL300817; SCHEMBL6254782; BDBM50045485; ZINC29559022; 4-(3-Pyridinyl)-N-(3-chlorophenyl)pyrimidin-2-amine; N-(3-chlorophenyl)-4-pyridin-3-ylpyrimidin-2-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
2-[4-(4-Methoxy-phenyl)-[1,2,3]triazol-1-yl]-1-phenylethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1277907; BDBM50334613; 1-(4-methoxyphenyl)-2-(4-phenyl-1h-1,2,3-triazol-1-yl) ethanone; 1-(4-methoxyphenyl)-2-(4-phenyl-1H-1,2,3-triazol-1-yl)ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
5-[4-Amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
eCF309; eCF-309; eCF 309; GTPL9571; CHEMBL3800481; SCHEMBL22773819; BDBM200300; cid_122163152; AKOS030211008; ZINC585672921; compound 12 [Fraser et al., 2016]; J3.595.265I
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
[4-[(2S)-3-[[(2S)-1-[[(2S)-4-Amino-1-[[(2S)-1-[(2S)-2-(butylcarbamoyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-oxo-2-(propanoylamino)propyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL367276; BDBM50074713
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[57] | |||
| Compound Name |
(2S,3R)-2-[[(2S)-2-[[(4S)-4-[[(2S)-2-Amino-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790812; BDBM50370346
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
1-(4-Methylpiperazin-1-yl)propan-2-yl N-(3-bromophenyl)-N-[6-methylsulfanyl-1-(2-phenylpropyl)pyrazolo[3,4-d]pyrimidin-4-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4084427; SCHEMBL17714367
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[83] | |||
| Compound Name |
(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-phenyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75049; SCHEMBL2461344; BDBM50051319; 5,6-dimethyl-N-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
5-(1H-Indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3358966
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
(3-Chloro-phenyl)-(6-methyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL308593; SCHEMBL2464688; BDBM50051309; N-(3-chlorophenyl)-6-methyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; N-(3-Chlorophenyl)-6-methyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[80] | |||
| Compound Name |
{[4-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-propyl)-methyl-carbamoyl]-propylcarbamoyl}-ethyl)-phenyl]-difluoro-methyl}-phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298813; BDBM50289746
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[82] | |||
| Compound Name |
5-Hydroxy-7-methoxy-3-(3-chlorophenyl)quinoline-4(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL440453; SCHEMBL8574371; BDBM50074744; 3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinolin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-Methoxy-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418010; SCHEMBL9666; BDBM50287096; VCC863136; 2-Methoxy-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
3-(4-Phosphonooxy-benzyl)-N-{1-[3-(4-trifluoromethyl-benzyl)-[1,2,4]oxadiazol-5-yl]-ethyl}-succinamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419539; BDBM50082330
Click to Show/Hide
|
||||
| Activity |
IC50 = 102000 nM
|
[53] | |||
| Compound Name |
7,8-Dimethoxy-3-(2-morpholin-4-yl-ethyl)-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL267180; BDBM50286757
Click to Show/Hide
|
||||
| Activity |
IC50 = 105000 nM
|
[94] | |||
| Compound Name |
2-(4-Phenyl-1H-1,2,3-triazol-1-yl)cyclopentanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642287; BDBM50334626; 2-(4-Phenyl-1H-1,2,3-triazole-1-yl)cyclopentanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 105500 nM
|
[61] | |||
| Compound Name |
N-((5-Bromo-1H-indol-3-yl)(4-methoxyphenyl)methyl)-N-methylaniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779751; BDBM50345184
Click to Show/Hide
|
||||
| Activity |
IC50 = 106000 nM
|
[47] | |||
| Compound Name |
1-(4-Chlorophenyl)-2-(4-p-tolyl-1H-1,2,3-triazol-1-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642272; BDBM50334616
Click to Show/Hide
|
||||
| Activity |
IC50 = 108700 nM
|
[61] | |||
| Compound Name |
8-Chloro-4-(3-chloro-4-fluorophenylamino)-6-((1-(1-cyclobutylpiperidin-4-yl)-1H-1,2,3-triazol-4-yl)methylamino)quinoline-3-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL501709; SCHEMBL4959879; BDBM29926; substituted 6-aminoquinoline-3-carbonitrile, 37
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[54] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[(1S)-1-[3-(3-methylbutyl)-1,2,4-oxadiazol-5-yl]propyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76812; BDBM50080188
Click to Show/Hide
|
||||
| Activity |
IC50 = 111000 nM
|
[60] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5g
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5067; CHEMBL130106
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[22] | |||
| Compound Name |
[(S)-1-[4-(3-Cyclohexyl-propyl)-5-oxo-[1,4]thiazepan-6-ylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL68300; BDBM50103053
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[75] | |||
| Compound Name |
[(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl]-1-(2-(4-methoxy-phenyl)-5-{[(naphthalen-1-ylmethyl)-carbamoyl]-methyl}-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL67271; BDBM50103040
Click to Show/Hide
|
||||
| Activity |
IC50 = 118000 nM
|
[75] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 14a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5086; CHEMBL130931
Click to Show/Hide
|
||||
| Activity |
IC50 = 123000 nM
|
[22] | |||
| Compound Name |
(2R,3S,4R,5S)-2-(Hydroxymethyl)-5-(4-phenylphenoxy)oxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205384; BDBM50401868
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[77] | |||
| Compound Name |
3-[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL57556; 3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzoic Acid; SCHEMBL1655099; BDBM50290410; ZINC29557832; 3-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid; 3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzoic acid; Benzoic acid,3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-
Click to Show/Hide
|
||||
| Activity |
IC50 = 126000 nM
|
[74] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 14c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5088; CHEMBL134004
Click to Show/Hide
|
||||
| Activity |
IC50 = 130000 nM
|
[22] | |||
| Compound Name |
3-(3-Chloro-4-methylphenyl)-2-(4-chlorophenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933748; BDBM50360653
Click to Show/Hide
|
||||
| Activity |
IC50 = 131800 nM
|
[48] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 12e
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5083; CHEMBL134030
Click to Show/Hide
|
||||
| Activity |
IC50 = 132000 nM
|
[22] | |||
| Compound Name |
{(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl]-1-[2-(4-methoxy-phenyl)-5-(naphthalen-1-ylcarbamoylmethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL302113; BDBM50103059
Click to Show/Hide
|
||||
| Activity |
IC50 = 133000 nM
|
[75] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(3S,6S,9R,20S)-6-[(2S)-Butan-2-yl]-3-[(4-hydroxyphenyl)methyl]-2,5,8,11,14-pentaoxo-9-(sulfanylmethyl)-1,4,7,10,15-pentazacycloicosane-20-carbonyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791378; BDBM50370739
Click to Show/Hide
|
||||
| Activity |
IC50 = 134000 nM
|
[56] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4i
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL310313; BDBM5063
Click to Show/Hide
|
||||
| Activity |
IC50 = 135000 nM
|
[22] | |||
| Compound Name |
1-(4-Chlorophenyl)-2-(4-phenyl-1H-1,2,3-triazol-1-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1277989; BDBM50334615; 1-(4-Chlorophenacyl)-4-phenyl-1H-1,2,3-triazole; 1-(4-Chloro-phenyl)-2-(4-phenyl-[1,2,3]triazol-1-yl)-ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 139000 nM
|
[61] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 14b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5087; CHEMBL133644
Click to Show/Hide
|
||||
| Activity |
IC50 = 143000 nM
|
[22] | |||
| Compound Name |
(2R,3S,4R,5S)-2-(Hydroxymethyl)-5-(4-methylphenoxy)oxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205388; BDBM50401866
Click to Show/Hide
|
||||
| Activity |
IC50 = 143400 nM
|
[77] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 12a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5082; CHEMBL133185
Click to Show/Hide
|
||||
| Activity |
IC50 = 149000 nM
|
[22] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(4-methoxyphenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933742; BDBM50360647
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-6,6-dimethyl-2-(4-methylphenyl)-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933732; BDBM50360636
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-6,6-dimethyl-2-(1H-pyrrol-2-yl)-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933735; BDBM50360639
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
N-((4-Chlorophenyl)(1H-indol-3-yl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779735; BDBM50345168; N-Methyl-N-phenyl-alpha-(4-chlorophenyl)-1H-indole-3-methaneamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
3-(4-Tert-butylphenyl)-2-(3,4-dimethoxyphenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933757; BDBM50360662
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(2-(4-p-Tolyl-1H-1,2,3-triazol-1-yl)acetyl)-2H-chromen-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642281; BDBM50334620
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[61] | |||
| Compound Name |
N,alpha-Diphenyl-N,1-dimethyl-1H-indole-3-methaneamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779743; BDBM50345176; N-Methyl-N-((1-methyl-1H-indol-3-yl)(phenyl)methyl)benzenamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
2-(4-Chlorophenyl)-3-cyclohexyl-6,6-dimethyl-[1,3]dioxino[4,5-c]pyrazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933753; BDBM50360658
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
N-((1H-Indol-3-yl)(p-tolyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779736; BDBM50345169; N-Phenyl-N-methyl-alpha-(4-methylphenyl)-1H-indole-3-methaneamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
3,5-Dihydroxy-N-(3-hydroxyphenyl)naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL145229; SCHEMBL2760104; CTK0J3197; DTXSID60610301; BDBM50086683; N-(3-Hydroxyphenyl)-3,5-dihydroxynaphthalene-2-carboxamide; 2-Naphthalenecarboxamide, 3,5-dihydroxy-N-(3-hydroxyphenyl)-; 3,5-Dihydroxy-naphthalene-2-carboxylic acid (3-hydroxy-phenyl)-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[95] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(4-hydroxyphenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933744; BDBM50360649
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
1-(2-Oxopropyl)-4-phenyl-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642283; BDBM50334622; 1-(4-phenyl-1H-1,2,3-triazol-1-yl)propan-2-one; 4-phenyl-1-(propan-2-on-1-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[61] | |||
| Compound Name |
6-(1,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420909; BDBM50439464; 9-(9H-purin-6-yl)-1,9-diazaspiro[5.5]undecane; Q27465376; SIJ
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[96] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(3-hydroxy-4-methoxyphenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933745; BDBM50360650
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-6,6-dimethyl-2-(4-nitrophenyl)-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933730; BDBM50360634
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
[4-[[(3S,6R,9S,12R,15S,22R)-15-Acetamido-6-(2-amino-2-oxoethyl)-9-(cyclohexylmethyl)-2,5,8,11,14,21-hexaoxo-3-propan-2-yl-1,4,7,10,13,20-hexazabicyclo[20.3.0]pentacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451250; BDBM50074717
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[57] | |||
| Compound Name |
N-((1H-Indol-3-yl)(4-hydroxy phenyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779739; BDBM50345172
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
N-Ethyl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642286; BDBM50334625
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[61] | |||
| Compound Name |
[4-[[(3S,6R,9S,12R,15S,22R)-15-Acetamido-6-(2-amino-2-oxoethyl)-3-(cyclohexylmethyl)-2,5,8,11,14,21-hexaoxo-9-propan-2-yl-1,4,7,10,13,20-hexazabicyclo[20.3.0]pentacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL355759; BDBM50074711
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[57] | |||
| Compound Name |
1-(4-Chlorophenyl)-2-(4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642275; BDBM50334617
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[61] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(3-hydroxy-4-methoxyphenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933733; BDBM50360637
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(4-nitrophenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933746; BDBM50360651
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
N-((5-Bromo-1H-indol-3-yl)(p-tolyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779750; BDBM50345183; N-Phenyl-N-methyl-alpha-(4-methylphenyl)-5-bromo-1H-indole-3-methaneamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
[4-[[(3S,6R,9S,12R,15S,22R)-15-Acetamido-6-(2-amino-2-oxoethyl)-9-(2-methylpropyl)-2,5,8,11,14,21-hexaoxo-3-propan-2-yl-1,4,7,10,13,20-hexazabicyclo[20.3.0]pentacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL177616; BDBM50074708
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[57] | |||
| Compound Name |
N-((5-Methoxy-1H-indol-3-yl)(p-tolyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779749; BDBM50345182; N-Phenyl-N-methyl-alpha-(4-methylphenyl)-5-methoxy-1H-indole-3-methaneamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
[4-[[(3S,6R,9S,12R,15S,22R)-15-Acetamido-6-(2-amino-2-oxoethyl)-2,5,8,11,14,21-hexaoxo-3,9-di(propan-2-yl)-1,4,7,10,13,20-hexazabicyclo[20.3.0]pentacosan-12-yl]methyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL435910; BDBM50074710
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[57] | |||
| Compound Name |
N-((1H-Indol-3-yl)(4-methoxyphenyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779737; BDBM50345170; N-Phenyl-N-methyl-alpha-(4-methoxyphenyl)-1H-indole-3-methaneamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
3-Cyclohexyl-6,6-dimethyl-2-(4-nitrophenyl)-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933752; BDBM50360657
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(4-Tert-butylphenyl)-2-(4-chlorophenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933758; BDBM50360663
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(3-Chloro-4-methylphenyl)-6,6-dimethyl-2-(1H-pyrrol-2-yl)-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933750; BDBM50360655
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-thiophen-2-yl-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933739; BDBM50360644
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
N-((1H-Indol-3-yl)(2,4-dimethoxyphenyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779742; BDBM50345175
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(4-methylphenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933740; BDBM50360645
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-6,6-dimethyl-2-thiophen-2-yl-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933731; BDBM50360635
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-2-(2-fluorophenyl)-6,7-dihydro-5H-indazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933741; BDBM50360646
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
1-(4-p-Tolyl-1H-1,2,3-triazol-1-yl)propan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642284; BDBM50334623
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[61] | |||
| Compound Name |
3-(4-Tert-butylphenyl)-6,6-dimethyl-2-(4-methylphenyl)-5,7-dihydroindazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933760; BDBM50360665
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
3-(4-Tert-butylphenyl)-2-(4-chlorophenyl)-6,6-dimethyl-[1,3]dioxino[4,5-c]pyrazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933759; BDBM50360664
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[48] | |||
| Compound Name |
N-((4-Hydroxy-3-bromophenyl)(1H-indol-3-yl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779740; BDBM50345173
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
N-((1H-Indol-3-yl)(3-methoxyphenyl)methyl)-N-methylbenzenamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779741; BDBM50345174
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[47] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4k
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76963; BDBM5064
Click to Show/Hide
|
||||
| Activity |
IC50 = 156000 nM
|
[22] | |||
| Compound Name |
N-[3-[(E)-2-[6-[3-(Dimethylamino)propylamino]purin-9-yl]ethenyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559068; SCHEMBL4128294; BDBM50294000
Click to Show/Hide
|
||||
| Activity |
IC50 = 159000 nM
|
[51] | |||
| Compound Name |
1-[2-(Furan-2-yl)pyrrolidin-1-yl]prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3617729; BDBM50119571
Click to Show/Hide
|
||||
| Activity |
Ki = 160000 nM
|
[97] | |||
| Compound Name |
AC-Dopa-eee
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370170; BDBM50118661
Click to Show/Hide
|
||||
| Activity |
IC50 = 160000 nM
|
[55] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 15a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5104; CHEMBL337737
Click to Show/Hide
|
||||
| Activity |
IC50 = 161000 nM
|
[22] | |||
| Compound Name |
[(S)-1-[5-(3-Cyclohexyl-propyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl]-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL304340; BDBM50103046
Click to Show/Hide
|
||||
| Activity |
IC50 = 164000 nM
|
[75] | |||
| Compound Name |
(S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-(3-isobutyl-[1,2,4]oxadiazol-5-yl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL309687; BDBM50080178
Click to Show/Hide
|
||||
| Activity |
IC50 = 166000 nM
|
[60] | |||
| Compound Name |
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-naphthalen-1-yloxyoxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205381; SCHEMBL6838084; BDBM50401871
Click to Show/Hide
|
||||
| Activity |
IC50 = 184700 nM
|
[77] | |||
| Compound Name |
2-(4-Hydroxyphenyl)-2-sulfoacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451544; SCHEMBL7898010; BDBM50113758; (4-Hydroxy-phenyl)-sulfo-acetic acid; alpha-Sulfo-4-hydroxybenzeneacetic acid; p-Hydroxy-alpha-sulfobenzeneacetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[91] | |||
| Compound Name |
alpha-Sulfophenylacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-phenyl-2-sulfoacetic acid; Benzeneacetic acid, a-sulfo-; PHENYL(SULFO)ACETIC ACID; Phenyl-sulfo-acetic acid; CHEMBL80333; Alpha-PhenylsulfoaceticAcid; Epitope ID:120380; alpha-sulphophenylacetic acid; 2-sulfo-2-phenylacetic acid; SCHEMBL11166146; BDBM14677; CTK4I4738; KS-00000FMG; DTXSID30328744; ACT06267; EBD37105; MFCD09952336; AKOS005203095; VZ31247; AC-23373; AK114033; AS-16021; FT-0655001; M-2000; S-9630; 360S321; Q27225710
Click to Show/Hide
|
||||
| Activity |
IC50 = 192000 nM
|
[91] | |||
| Compound Name |
5-[(3,4-Dichlorophenyl)methyl]-2,3,7,8-tetrahydroxyphenanthridin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Phenanthridinone deriv. 5j; CHEMBL71206; BDBM4088; SCHEMBL7987637; 2,3,7,8-Tetrahydroxy-5-(3,4-dichlorobenzyl)phenanthridin-6(5H)-one; 5-[(3,4-dichlorophenyl)methyl]-2,3,7,8-tetrahydroxy-5,6-dihydrophenanthridin-6-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 197000 nM
|
[59] | |||
| Compound Name |
[5-[[(1S)-1-[3-[(3,4-Dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]ethyl]carbamoylamino]naphthalen-2-yl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL319179; BDBM50082326
Click to Show/Hide
|
||||
| Activity |
IC50 = 198000 nM
|
[53] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 5h
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5068; CHEMBL133511
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[22] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 73 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Tpl2 kinase inhibitor
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Tpl2 Kinase Inhibitor; 871307-18-5; 4-((3-Chloro-4-fluorophenyl)amino)-6-((pyridin-3-ylmethyl)amino)-1,7-naphthyridine-3-carbonitrile; CHEMBL200381; 4-[(3-CHLORO-4-FLUOROPHENYL)AMINO]-6-[(3-PYRIDINYLMETHYL)AMINO]-1,7-NAPHTHYRIDINE-3-CARBONITRILE; 4-(3-Chloro-4-fluorophenylamino)-6-(pyridin-3-yl-methylamino)-3-cyano-[1,7]-naphthyridine; K00599a; 4-[(3-chloro-4-fluorophenyl)amino]-6-[(pyridin-3-ylmethyl)amino]-1,7-naphthyridine-3-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[76] | |||
| Compound Name |
Ac-YEEIE
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329886; BDBM50118653
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[55] | |||
| Compound Name |
(E)-N-(4-Methyl-3-(2-(6-(pyridine-2-yl-amino)-9H-purin-9-yl)vinyl)phenyl)-3-(trifluoromethyl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551030; SCHEMBL4128265; SCHEMBL4128274; BDBM50293995; N-[4-methyl-3-[(E)-2-[6-(pyridin-2-ylamino)purin-9-yl]ethenyl]phenyl]-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 201000 nM
|
[51] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4d
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5059; CHEMBL336978
Click to Show/Hide
|
||||
| Activity |
IC50 = 205000 nM
|
[22] | |||
| Compound Name |
[4-[(2S)-2-(Tert-butylsulfonylmethyl)-3-oxo-3-[[(1S)-1-[3-[[4-(trifluoromethyl)phenyl]methyl]-1,2,4-oxadiazol-5-yl]ethyl]amino]propyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320372; BDBM50082331
Click to Show/Hide
|
||||
| Activity |
IC50 = 205000 nM
|
[53] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4f
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5093; CHEMBL337459
Click to Show/Hide
|
||||
| Activity |
IC50 = 206000 nM
|
[22] | |||
| Compound Name |
(S)-4-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-(4-isobutyl-thiazol-2-yl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77116; BDBM50080185
Click to Show/Hide
|
||||
| Activity |
IC50 = 218000 nM
|
[60] | |||
| Compound Name |
(2R,3S,4R,5S)-2-(Hydroxymethyl)-5-naphthalen-2-yloxyoxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205382; BDBM50401870
Click to Show/Hide
|
||||
| Activity |
IC50 = 224800 nM
|
[77] | |||
| Compound Name |
(4S)-4-[[(2S)-2-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-amino-4-oxobutanoyl]amino]-5-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL430059
Click to Show/Hide
|
||||
| Activity |
IC50 = 237000 nM
|
[22] | |||
| Compound Name |
3-(2-{(S)-1-[(S)-1-((S)-(S)-1-Carbamoyl-2-methyl-butylcarbamoyl)-3-carboxy-propylcarbamoyl]-3-carboxy-propylcarbamoyl}-ethyl)-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL297011; BDBM50101082
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[87] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4e
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5060; CHEMBL423330
Click to Show/Hide
|
||||
| Activity |
IC50 = 259000 nM
|
[22] | |||
| Compound Name |
(3S)-3-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL336957
Click to Show/Hide
|
||||
| Activity |
IC50 = 261000 nM
|
[22] | |||
| Compound Name |
(2R,3S,4R,5S)-2-(Hydroxymethyl)-5-(4-hydroxyphenoxy)oxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205394; SCHEMBL6842150; BDBM50401863
Click to Show/Hide
|
||||
| Activity |
IC50 = 272100 nM
|
[77] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4j
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5094; CHEMBL134243
Click to Show/Hide
|
||||
| Activity |
IC50 = 274000 nM
|
[22] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[(1S)-2-(1H-indol-3-yl)-1-[3-(naphthalen-1-ylmethyl)-1,2,4-oxadiazol-5-yl]ethyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL263245; BDBM50080176
Click to Show/Hide
|
||||
| Activity |
IC50 = 279000 nM
|
[60] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 12d
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5100; CHEMBL334979
Click to Show/Hide
|
||||
| Activity |
IC50 = 282000 nM
|
[98] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5057; CHEMBL130401
Click to Show/Hide
|
||||
| Activity |
IC50 = 292000 nM
|
[22] | |||
| Compound Name |
3H-Pyrimido[4,5-B]indol-4(9H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL267004; 3,9-Dihydro-4H-pyrimido[4,5-b]indol-4-one; 1,9-dihydropyrimido[4,5-b]indol-4-one; 3H,4H,9H-pyrimido[4,5-b]indol-4-one; 3,9-Dihydro-pyrimido[4,5-b]indol-4-one; Oprea1_100782; Oprea1_379532; SCHEMBL3123673; CTK7H0290; 4-hydroxyindolo[2,3-d)pyrimidine; 4-oxo-9h-pyrimido[4,5-b]indole; BDBM50286751; MFCD01568664; ZINC16849964; 3-hydropyrimidino[4,5-b]indol-4-one; AKOS024015237; MCULE-6179925480; 3H-pyrimido[4,5-b]indole-4(9H)-on; ST088553; CS-0109610; SR-01000522008; 3,9-DIHYDRO-1,3,9-TRIAZA-FLUOREN-4-ONE; SR-01000522008-1; Z2235810179
Click to Show/Hide
|
||||
| Activity |
IC50 = 293000 nM
|
[94] | |||
| Compound Name |
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-naphthalen-2-yloxyoxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205383; BDBM50401869
Click to Show/Hide
|
||||
| Activity |
IC50 = 297300 nM
|
[77] | |||
| Compound Name |
Phosphoric acid mono-(8-hydroxy-3,4-dihydro-2H-quinolin-1-yl) ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL26549; BDBM50112464
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[99] | |||
| Compound Name |
(3S,6S,9S,12S,15S,18S,21S,24S)-3,9,15,21-Tetrakis(4-aminobutyl)-6,12,18,24-tetramethyl-1,4,7,10,13,16,19,22-octazacyclotetracosane-2,5,8,11,14,17,20,23-octone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2382021
Click to Show/Hide
|
||||
| Activity |
IC50 >= 300000 nM
|
[52] | |||
| Compound Name |
3-[(2S,5S,8S,11S,14S,17S,20S,23S)-5,11,17,23-Tetrakis(4-aminobutyl)-8,14,20-tris(2-carboxyethyl)-3,6,9,12,15,18,21,24-octaoxo-1,4,7,10,13,16,19,22-octazacyclotetracos-2-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2382011
Click to Show/Hide
|
||||
| Activity |
IC50 >= 300000 nM
|
[52] | |||
| Compound Name |
[Hydroxy-(6-nitro-1,3-benzodioxol-5-yl)methyl]phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL346901
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[100] | |||
| Compound Name |
N-(4-Methyl-3-(2-(6-(methylamino)-9H-purin-9-yl)ethyl)phenyl)-3-(trifluoromethyl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL550623; SCHEMBL4131786; BDBM50294015; N-[4-methyl-3-[2-[6-(methylamino)purin-9-yl]ethyl]phenyl]-3-(trifluoromethyl)benzamide; N-(4-Methyl-3-(2-(6-(methylamino)-9H-purin-9-yl)ethyl)phenyl)-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[51] | |||
| Compound Name |
3-[(2S,5S,8S,11S,14S,17S,20S,23S)-5,11,17,23-Tetrabenzyl-14-(2-carboxyethyl)-8,20-bis[3-(diaminomethylideneamino)propyl]-3,6,9,12,15,18,21,24-octaoxo-1,4,7,10,13,16,19,22-octazacyclotetracos-2-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2382022
Click to Show/Hide
|
||||
| Activity |
IC50 >= 300000 nM
|
[52] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[(1S)-1-[3-(cyclohexylmethyl)phenyl]propyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76250; BDBM50080170
Click to Show/Hide
|
||||
| Activity |
IC50 = 306000 nM
|
[101] | |||
| Compound Name |
N-(5-Tert-butyl-1,3-thiazol-2-yl)-3-[(E)-2-[6-(cyclopropylamino)purin-9-yl]ethenyl]-4-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559438; BDBM50294007; (E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-(5-(tert-butyl)thiazo-2-yl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 310000 nM
|
[51] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[(1S)-4-amino-4-oxo-1-[3-[(4,6,6-trimethylcyclohexa-2,4-dien-1-yl)methyl]-1,2,4-oxadiazol-5-yl]butyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL134191
Click to Show/Hide
|
||||
| Activity |
IC50 = 312000 nM
|
[22] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[(1S)-4-amino-1-[3-(3-methylbutyl)-1,2,4-oxadiazol-5-yl]-4-oxobutyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76201; BDBM50080194
Click to Show/Hide
|
||||
| Activity |
IC50 = 320000 nM
|
[60] | |||
| Compound Name |
Benzyl [4-[3-[[2-(4-methoxyphenyl)-5-[2-(naphthalen-1-ylmethylamino)-2-oxoethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl]amino]-3-oxopropyl]phenyl] hydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL304745; BDBM50103061
Click to Show/Hide
|
||||
| Activity |
IC50 = 339000 nM
|
[75] | |||
| Compound Name |
(4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-phenoxy)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75182; BDBM50103787
Click to Show/Hide
|
||||
| Activity |
IC50 = 370000 nM
|
[102] | |||
| Compound Name |
{4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-benzylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL263721; BDBM50103785
Click to Show/Hide
|
||||
| Activity |
IC50 = 378000 nM
|
[102] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[(1S)-4-amino-1-(3-butyl-1,2,4-oxadiazol-5-yl)-4-oxobutyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75974; BDBM50080191
Click to Show/Hide
|
||||
| Activity |
IC50 = 384000 nM
|
[60] | |||
| Compound Name |
(2-Formyl-4-methyl-phenyl)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL80192; BDBM50113766
Click to Show/Hide
|
||||
| Activity |
IC50 = 385000 nM
|
[91] | |||
| Compound Name |
4-({(S)-1-[(Benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-2-phenyl-ethylcarbamoyl}-methoxy)-pyridine-2,6-dicarboxylic acid dimethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL365906; BDBM50150357
Click to Show/Hide
|
||||
| Activity |
IC50 = 396000 nM
|
[103] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-aminohexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791370; BDBM50370738
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[56] | |||
| Compound Name |
Cyclo[Ac-Cys-Ile-Tyr-Lys-Phe]-Tyr
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL378962; BDBM50187724
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[56] | |||
| Compound Name |
(2S)-2-[[(12S,15S)-12-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,6,13-trioxo-2,7,14-triazabicyclo[15.2.2]henicosa-1(19),17,20-triene-15-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791366; BDBM50370741
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[56] | |||
| Compound Name |
[(R)-1-[5-(3-Cyclohexyl-propyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL66442; BDBM50103067
Click to Show/Hide
|
||||
| Activity |
IC50 = 422000 nM
|
[75] | |||
| Compound Name |
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(3-methylphenoxy)oxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205387; BDBM50401867
Click to Show/Hide
|
||||
| Activity |
IC50 = 451000 nM
|
[77] | |||
| Compound Name |
N-[(S)-1-[3-(3,4-Dichlorobenzyl)-1,2,4-oxadiazole-5-yl]ethyl]-4-(phosphonooxy)benzenepropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419353; BDBM50082329
Click to Show/Hide
|
||||
| Activity |
IC50 = 459000 nM
|
[53] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[4-(cyclohexylmethyl)-1,3-thiazol-2-yl]methylamino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76625; BDBM50080169
Click to Show/Hide
|
||||
| Activity |
IC50 = 483000 nM
|
[60] | |||
| Compound Name |
(2R,3S,4R,5S)-2-(Hydroxymethyl)-5-(4-methoxyphenoxy)oxolane-3,4-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205392; SCHEMBL1178662; BDBM50401864
Click to Show/Hide
|
||||
| Activity |
IC50 = 483900 nM
|
[77] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 6
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5076; CHEMBL131768
Click to Show/Hide
|
||||
| Activity |
IC50 = 489000 nM
|
[22] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 4g
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5061; CHEMBL341314
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[22] | |||
| Compound Name |
(5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-hydroxy-phenyl)-phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76937; BDBM50103788
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[102] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 7
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5077; CHEMBL132014
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[22] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 8
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5078; CHEMBL130751
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[22] | |||
| Compound Name |
[5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-(tetrazol-1-ylmethoxy)-phenyl]-phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL311114; BDBM50103778
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[102] | |||
| Compound Name |
Trifluoro-methanesulfonic acid 4-{2-[1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL430825; BDBM50103779
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[102] | |||
| Compound Name |
1,2,4-Oxadiazole Analogue 9
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM5079; CHEMBL132963
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[22] | |||
| Compound Name |
{4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-phenylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL308164; BDBM50103783
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[102] | |||
| Compound Name |
Phosphoric acid 2,6-diformylphenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL279466; BDBM50112470; Phosphoric acid mono-(2,6-diformyl-phenyl) ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[99] | |||
| Compound Name |
(E)-1-(3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methylphenyl)-3-(3-(trifluoromethyl)phenyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559069; SCHEMBL4129293; SCHEMBL4129297; BDBM50294002
Click to Show/Hide
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| Activity |
IC50 = 517000 nM
|
[51] | |||
| Compound Name |
10-Ethyl-5,10-dihydro-3H-pyrimido[4,5-b]quinolin-4-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL7404; BDBM50286754; 4-hydroxy-10-ethyl-5,10-dihydropyrimido[4,5-b]quinoline
Click to Show/Hide
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| Activity |
IC50 = 550000 nM
|
[94] | |||
| Compound Name |
4-Aminophenyl phosphate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
(4-aminophenyl) dihydrogen phosphate; CHEMBL287216; p-aminophenol phosphate; SCHEMBL61616; 4-aminophenyl dihydrogen phosphate; ZINC2558168; BDBM50112456; FT-0600240; Phenol, 4-amino-, 1-(dihydrogen phosphate); Phosphoric acid mono-(4-amino-phenyl) ester
Click to Show/Hide
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| Activity |
IC50 = 600000 nM
|
[99] | |||
| Compound Name |
Phosphoric acid 3-formylphenyl ester
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL287306; BDBM50112457; (3-formylphenyl) dihydrogen phosphate; Phosphoric acid mono-(3-formyl-phenyl) ester
Click to Show/Hide
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||||
| Activity |
IC50 = 600000 nM
|
[91] | |||
| Compound Name |
4-{[(S)-1-(3-Methoxy-benzylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methoxy}-pyridine-2,6-dicarboxylic acid dimethyl ester
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL183397; BDBM50150359
Click to Show/Hide
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||||
| Activity |
IC50 = 663000 nM
|
[103] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-aminohexanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791357; BDBM50370726
Click to Show/Hide
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||||
| Activity |
IC50 > 700000 nM
|
[56] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-aminohexanoyl]amino]-3-[4-(methanesulfonamido)phenyl]propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791363; BDBM50370723
Click to Show/Hide
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||||
| Activity |
IC50 > 700000 nM
|
[56] | |||
| Compound Name |
Ac-Cys-Tyr-Lys-Tyr(4-PO3H2)-Tyr
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL378042; BDBM50187744
Click to Show/Hide
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||||
| Activity |
IC50 > 700000 nM
|
[56] | |||
| Compound Name |
Ac-Cys-Ile-Tyr-Lys-Tyr(4-PO3H2)-Tyr
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL380085; BDBM50187725
Click to Show/Hide
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||||
| Activity |
IC50 > 700000 nM
|
[56] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-aminohexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-aminophenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791355; BDBM50370734
Click to Show/Hide
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||||
| Activity |
IC50 > 700000 nM
|
[56] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-aminohexanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791377; BDBM50370733
Click to Show/Hide
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||||
| Activity |
IC50 > 700000 nM
|
[56] | |||
| Compound Name |
Asp-Arg-Val-Tyr-Val-His-Pro-Phe
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
Val(5)-angiotensin II; Angiotensin II 5-valine; (Val5)-Angiotensin II; bovine angiotensin II; CHEMBL216830; (Val5)angiotensin II; AspArgValTyrValHisProPh; [Val5] - ANGIOTENSIN II; HY-P0108; BDBM50048128; MFCD00167495; CS-5786; 58A491; Asp-Arg-Val-Tyr-Val-His-Pro-Phe (Angiotensin II); Q27121202; [Asp1-Arg2-Val3-Tyr4-Val5-His6-Pro7-Phe8](angiotensin II)
Click to Show/Hide
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||||
| Activity |
Ki = 700000 nM
|
[90] | |||
| Compound Name |
4-{[(S)-1-(3-Methoxy-benzylcarbamoyl)-2-methyl-propylcarbamoyl]-methoxy}-pyridine-2,6-dicarboxylic acid dimethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL185409; BDBM50150356
Click to Show/Hide
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||||
| Activity |
IC50 = 713000 nM
|
[103] | |||
| Compound Name |
4-[({(S)-[(Benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-phenyl-methyl}-carbamoyl)-methoxy]-pyridine-2,6-dicarboxylic acid dimethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL359728; BDBM50150355
Click to Show/Hide
|
||||
| Activity |
IC50 = 714000 nM
|
[103] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-3-(4-aminophenyl)propanoyl]amino]-6-aminohexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791359; BDBM50370740
Click to Show/Hide
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||||
| Activity |
IC50 = 760000 nM
|
[56] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[3-(cyclohexylmethyl)phenyl]methylamino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL308344; BDBM50080172
Click to Show/Hide
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||||
| Activity |
IC50 = 769000 nM
|
[101] | |||
| Compound Name |
4-(Benzyloxy)phenylcarbamoylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL24656; BDBM50112450; {[4-(benzyloxy)phenyl]amino}carbonylphosphonic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 800000 nM
|
[99] | |||
| Compound Name |
5-{[(S)-1-(4-Methoxy-benzylcarbamoyl)-3-methyl-butylcarbamoyl]-methoxy}-isophthalic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL435293; BDBM50150358
Click to Show/Hide
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||||
| Activity |
IC50 = 864000 nM
|
[103] | |||
| Compound Name |
{(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl]-1-[2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306655; BDBM50103060
Click to Show/Hide
|
||||
| Activity |
IC50 = 873000 nM
|
[75] | |||
| Compound Name |
[4-[(2S)-2-Acetamido-3-[[3-(cyclohexylmethyl)-1,2,4-oxadiazol-5-yl]methylamino]-3-oxopropyl]phenyl] dihydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL80769; BDBM50080200
Click to Show/Hide
|
||||
| Activity |
IC50 = 896000 nM
|
[60] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 83 | Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model. J Med Chem. 2017 Jul 27;60(14):6305-6320. | ||||
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