Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T86918 | Target Info | |||
Target Name | Pancreatic alpha-amylase (AMY2A) | ||||
Synonyms |
PA; 1,4-alpha-D-glucan glucanohydrolase
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Target Type | Clinical trial Target | ||||
Gene Name | AMY2A | ||||
Biochemical Class | Glycosylase | ||||
UniProt ID |
Non Binders of This Target (in total, 2 non binders) | Download | Top | |||
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Compound Name |
D-Gluconhydroximo-1,5-Lactam
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Investigative | Compound Info | ||
Synonyms |
D-GLUCONHYDROXIMO-1,5-LACTAM; CHEMBL1213470; (Z)-D-Gluconhydroximo-1,5-lactam; GOX; (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL; CID445248; GHIL; 1e6s; AC1L9HO3; BDBM36390; 3d51; 2j78; BDBM50120840; DB02376; (Z)-D-Gluconhydroximo-1,5-lactam, 15; (2Z,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)piperidin-2-one oxime
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Activity |
Ki = 18000000 nM
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[1] | |||
Compound Name |
Maltosyl-alpha (1,4)-(Z,3S,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-piperidin-2-one oxime
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Investigative | Compound Info | ||
Synonyms |
CHEMBL1233953; MALTOSYL-ALPHA (1,4)-D-GLUCONHYDROXIMO-1,5-LACTAM; BDBM50120838; DB01922; Q27462363
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Activity |
Ki = 1800000 nM
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[1] |
References | Top | ||||
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REF 1 | From carbohydrates to drug-like fragments: Rational development of novel alpha-amylase inhibitors. Bioorg Med Chem. 2015 Oct 15;23(20):6725-32. |
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