Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
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| Target ID | T89055 | Target Info | |||
| Target Name | ERK activator kinase 2 (MEK2) | ||||
| Synonyms |
PRKMK2; MKK2; MEK 2; MAPKK 2; MAPK/ERK kinase 2; MAP kinase kinase 2; Dual specificity mitogenactivated protein kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 2
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| Target Type | Clinical trial Target | ||||
| Gene Name | MAP2K2 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
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Investigative | Compound Info | ||
| Synonyms |
PD98059; PD 98059; 2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one; PD 98,059; PD-98059; 2-(2-amino-3-methoxyphenyl)chromen-4-one; 2'-AMINO-3'-METHOXYFLAVONE; PD-098059; UNII-SJE1IO5E3I; SJE1IO5E3I; CHEMBL35482; C16H13NO3; MFCD00671789; 2-(2-Amino-3-methoxy-phenyl)-chromen-4-one; SR-01000076097; PD 098059; 2-(2-Amino-3-methoxyphenyl)-chromen-4-one; NSC 679829; 2'-Amino-3'-methoxyflavone; Tocris-1213; Lopac-P-215; BiomolKI_000001; 2-(2-amino-3-methoxy-phenyl)chromen-4-one; BiomolKI2_000011; PD 98,059, solid; Lopac0_001028; BMK1-B1; BSPBio_000996; KBioGR_000336; KBioSS_000336; cc-461; MLS006010134; SCHEMBL157826; GTPL5241; QCR-14; 2''-amino-3''-methoxyflavone; BCBcMAP01_000049; CTK4D2796; KBio2_000336; KBio2_002904; KBio2_005472; KBio3_000671; KBio3_000672; KS-00000GVZ; AOB2598; DTXSID40168416; BCPP000123; Bio1_000475; Bio1_000964; Bio1_001453; Bio2_000338; Bio2_000818; HMS1362B17; HMS1792B17; HMS1990B17; HMS3229M08; HMS3263M17; HMS3267D03; HMS3403B17; HMS3412O09; HMS3649N14; HMS3654I16; HMS3676O09; BCP02423; EX-A2127; ZINC1420826; Tox21_501028; ABP000927; BDBM50108771; NSC679828; s1177; AKOS015995212; BCP9001060; CCG-100605; CS-0169; LP01028; NSC 679828; NSC-679828; SB16629; SDCCGSBI-0051000.P003; IDI1_002093; SMP2_000052; NCGC00015790-01; NCGC00015790-02; NCGC00015790-03; NCGC00015790-04; NCGC00015790-05; NCGC00015790-06; NCGC00015790-07; NCGC00015790-08; NCGC00025045-01; NCGC00025045-02; NCGC00025045-03; NCGC00025045-04; NCGC00025045-05; NCGC00179347-01; NCGC00261713-01; AC-28412; AK-60664; AS-19374; HY-12028; NCI60_028554; SC-96623; SMR001456459; AB0033706; EU-0101028; FT-0716482; P-215; PD-98059/PD98059/; SW218254-2; X7398; EC-000.2425; A25454; P-4313; PD 98059 & Z-100; InSolution PD 98059 - CAS 167869-21-8; J-505513; SR-01000076097-1; SR-01000076097-3; SR-01000076097-6; BRD-K62810658-001-05-6; BRD-K62810658-001-06-4; Q27088281; PD 98059 - CAS 167869-21-8
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| Activity |
IC50 = 50000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | Truncated militarinone fragments identified by total chemical synthesis induce neurite outgrowth. Medchemcomm. 2013;4:135-9. | ||||
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