Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T98092 | Target Info | |||
| Target Name | HUMAN cyclophilin A (CYPA) | ||||
| Synonyms |
PPIA; Cyclophilin A; CyPA
Click to Show/Hide
|
||||
| Gene Name | PPIA | ||||
| Biochemical Class | Cis-trans-isomerases | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 6 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(2R)-N-[2-(Benzylcarbamoyl)cyclopentyl]-1-[2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-methylbutanoylamino)propanoyl]amino]propanoyl]amino]acetyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358925; BDBM50121238
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[1] | |||
| Compound Name |
(2S)-N-[1-(Benzylcarbamoyl)cyclopentyl]-1-[2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-methylbutanoylamino)propanoyl]amino]propanoyl]amino]acetyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1793898; BDBM50369808; Dav-His-Ala-Gly-Pro-Acp-NH-CH2-Ph; 1-[[N-(3-Methylbutanoyl)-L-His-L-Ala-Gly-L-Pro-]amino]-N-benzylcyclopentane-1-carboxamide; Deaminovaline (isovaleric acid)-His-Ala-Gly-Pro-2-aminocyclopentanecarboxylate-NH-CH2-Ph
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[2] | |||
| Compound Name |
Ac-Val-His-Ala-Gly-Pro-Ile-NH-CH2-Ph
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790326; BDBM50369806
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[2] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-(benzylamino)-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL263062; BDBM50121242
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[1] | |||
| Compound Name |
(2R)-N-[(2S,3S)-1-[[(2S)-1-Amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]-1-[2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-methylbutanoylamino)propanoyl]amino]propanoyl]amino]acetyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL434694; BDBM50121227
Click to Show/Hide
|
||||
| Activity |
IC50 = 165000 nM
|
[1] | |||
| Compound Name |
(2S)-N-[(2S,3S)-1-[[(2R)-1-Amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]-1-[2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-methylbutanoylamino)propanoyl]amino]propanoyl]amino]acetyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790324; BDBM50369804
Click to Show/Hide
|
||||
| Activity |
IC50 = 165000 nM
|
[2] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 38 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-(benzylamino)-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149224; BDBM50121235
Click to Show/Hide
|
||||
| Activity |
IC50 = 260000 nM
|
[1] | |||
| Compound Name |
Val-His-Ala-Gly-Pro-Ile-NH-CH2-Ph
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790327; BDBM50369803
Click to Show/Hide
|
||||
| Activity |
IC50 = 260000 nM
|
[2] | |||
| Compound Name |
Ac-His-Ala-Gly-Pro-Ile-NH-CH2-Ph
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790319; BDBM50369816
Click to Show/Hide
|
||||
| Activity |
IC50 = 280000 nM
|
[2] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-Acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-(benzylamino)-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151381; BDBM50121236
Click to Show/Hide
|
||||
| Activity |
IC50 = 280000 nM
|
[1] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-3-methyl-1-oxo-1-(2-phenylethylamino)pentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151385; BDBM50121234
Click to Show/Hide
|
||||
| Activity |
IC50 = 325000 nM
|
[1] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-(3,3-diphenylpropylamino)-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433738; BDBM50121233
Click to Show/Hide
|
||||
| Activity |
IC50 = 365000 nM
|
[1] | |||
| Compound Name |
(2R)-N-[2-(Benzylcarbamoyl)cyclopentyl]-1-[2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-methylbutanoylamino)propanoyl]amino]-3-methylbutanoyl]amino]acetyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358023; BDBM50121232
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[1] | |||
| Compound Name |
Dav-His-Aib-Gly-Pro-Acp-NH-CH2-Ph
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1793899; BDBM50369805; 1-[[N-(3-Methylbutanoyl)-L-His-Aib-Gly-L-Pro-]amino]-N-benzylcyclopentane-1-carboxamide; Deaminovaline-His-2-aminoisobutyrate-Gly-Pro-2-aminocyclopentanecarboxylate-NH-CH2-Ph
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[2] | |||
| Compound Name |
Ac-Val-His-Ala-Gly-Pro-Acp-Ala-NH2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1793897; BDBM50369817; Ac-Val-His-Ala-Gly-Pro-2-aminocyclopentanecarboxylate-Ala-NH2
Click to Show/Hide
|
||||
| Activity |
IC50 = 680000 nM
|
[2] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]cyclopentyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2371033; BDBM50121226
Click to Show/Hide
|
||||
| Activity |
IC50 = 680000 nM
|
[1] | |||
| Compound Name |
(2S)-1-[2-[[2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-2-methylpropanoyl]amino]acetyl]-N-[(2R,3R)-1-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL300523; BDBM50087868
Click to Show/Hide
|
||||
| Activity |
IC50 = 760000 nM
|
[2] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-methylbutanoyl]amino]acetyl]-N-[(2S,3S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358478; BDBM50121222
Click to Show/Hide
|
||||
| Activity |
IC50 = 760000 nM
|
[1] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(1R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-2-oxo-1-phenylethyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148477; BDBM50121240
Click to Show/Hide
|
||||
| Activity |
IC50 = 820000 nM
|
[1] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(1S)-2-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-2-oxo-1-phenylethyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295942; BDBM50087875
Click to Show/Hide
|
||||
| Activity |
IC50 = 820000 nM
|
[2] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2R,3R)-1-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52165; BDBM50087882
Click to Show/Hide
|
||||
| Activity |
IC50 = 850000 nM
|
[2] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151384; BDBM50121237
Click to Show/Hide
|
||||
| Activity |
IC50 = 850000 nM
|
[1] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(1S)-2-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-2-oxo-1-phenylethyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151360; BDBM50121225
Click to Show/Hide
|
||||
| Activity |
IC50 = 970000 nM
|
[1] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(1R)-2-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-2-oxo-1-phenylethyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL300089; BDBM50087855
Click to Show/Hide
|
||||
| Activity |
IC50 = 970000 nM
|
[2] | |||
| Compound Name |
N-{1-[1-[1-(2-{2-[1-(1-Carbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-pyrrolidin-1-yl}-2-oxo-ethylcarbamoyl)-ethylcarbamoyl]-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-2-methyl-propyl}-succinamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3085530; BDBM50121231; Suc-Val-His-Ala-Gly-Pro-Ile-Ala-NH2; Succinyl-Val-His-Ala-Gly-Pro-Ile-Ala-NH2
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[1] | |||
| Compound Name |
(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-N-[(2R)-1-amino-1-oxopropan-2-yl]pentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424038; BDBM50087854
Click to Show/Hide
|
||||
| Activity |
IC50 = 1300000 nM
|
[2] | |||
| Compound Name |
(2S)-2-[[(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-amino-1-oxopropan-2-yl]pentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL356248; BDBM50121243
Click to Show/Hide
|
||||
| Activity |
IC50 = 1300000 nM
|
[1] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-(benzhydrylamino)-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790325; BDBM50369807
Click to Show/Hide
|
||||
| Activity |
IC50 = 1500000 nM
|
[2] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341860; BDBM50121239
Click to Show/Hide
|
||||
| Activity |
IC50 = 1500000 nM
|
[1] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S)-1-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL297131; BDBM50087874
Click to Show/Hide
|
||||
| Activity |
IC50 = 1500000 nM
|
[2] | |||
| Compound Name |
(2R)-2-[[(2S,3S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-Amino-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790322; BDBM50369814
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[2] | |||
| Compound Name |
2-(2-{[1-(2-{2-[2-Amino-3-(3H-imidazol-4-yl)-propionylamino]-propionylamino}-acetyl)-pyrrolidine-2-carbonyl]-amino}-3-methyl-pentanoylamino)-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL356871; His-Ala-Gly-Pro-Ile-Ala-NH2; His87-Ala-Gly-Pro-Ile-Ala92; BDBM50121224
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[1] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790309; BDBM50369813
Click to Show/Hide
|
||||
| Activity |
IC50 = 2100000 nM
|
[2] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151816; BDBM50121229
Click to Show/Hide
|
||||
| Activity |
IC50 = 2100000 nM
|
[1] | |||
| Compound Name |
(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-N-[(2S)-1-[[2-[(2R)-2-[[(2S,3S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxopropan-2-yl]pentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL150749; BDBM50121241
Click to Show/Hide
|
||||
| Activity |
IC50 = 2500000 nM
|
[1] | |||
| Compound Name |
(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-N-[(2S)-1-[[2-[(2S)-2-[[(2R,3R)-1-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxopropan-2-yl]pentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL49783; BDBM50087872
Click to Show/Hide
|
||||
| Activity |
IC50 = 2500000 nM
|
[2] | |||
| Compound Name |
(2R)-N-[(2S,3S)-1-[[(2S)-1-Amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]-1-[2-[[(2S)-2-[3-(1H-imidazol-5-yl)propanoylamino]propanoyl]amino]acetyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148546; BDBM50121230
Click to Show/Hide
|
||||
| Activity |
IC50 = 2600000 nM
|
[1] | |||
| Compound Name |
(2S)-N-[(2S,3S)-1-[[(2R)-1-Amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]-1-[2-[[(2S)-2-[3-(1H-imidazol-5-yl)propanoylamino]propanoyl]amino]acetyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790323; BDBM50369815
Click to Show/Hide
|
||||
| Activity |
IC50 = 2600000 nM
|
[2] | |||
| Compound Name |
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[2-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-2-oxoethyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148657; BDBM50121223
Click to Show/Hide
|
||||
| Activity |
IC50 = 2800000 nM
|
[1] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[2-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-2-oxoethyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433082; BDBM50087866
Click to Show/Hide
|
||||
| Activity |
IC50 = 2800000 nM
|
[2] | |||
| Compound Name |
4-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-N-[(2R)-1-amino-1-oxopropan-2-yl]piperidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296587; BDBM50087870
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[2] | |||
| Compound Name |
Dah-Ala-GLy-PrIle-NH-CH2-Ph
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790318; BDBM50369818; Deaminohistidine (dihydrourocanic acid)-Ala-GLy-Pro-Ile-NH-CH2-Ph
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[2] | |||
| Compound Name |
Dav-His-Aib-Gly-Pro-Ile-NH-CH2-Ph
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL432322; BDBM50087857; Deaminovaline-His-Aib-Gly-Pro-Ile-NH-CH2-Ph
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[2] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[1-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-2-methyl-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL276363; BDBM50087873
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[2] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Molecular docking and 3D-QSAR studies on gag peptide analogue inhibitors interacting with human cyclophilin A. J Med Chem. 2002 Nov 21;45(24):5249-59. | ||||
| REF 2 | Design of a Gag pentapeptide analogue that binds human cyclophilin A more efficiently than the entire capsid protein: new insights for the development of novel anti-HIV-1 drugs. J Med Chem. 2000 May 4;43(9):1770-9. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.