Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T99912 | Target Info | |||
| Target Name | Kynureninase (KYNU) | ||||
| Synonyms |
L-kynurenine hydrolase; KYNU
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| Target Type | Preclinical Target | ||||
| Gene Name | KYNU | ||||
| Biochemical Class | Carbon-carbon bonds hydrolase | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-[(Benzyloxy)carbonyl]-3-[methoxy(phenyl)phosphoryl]-L-alanine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL85072; CTK0A4460; DTXSID50658292; BDBM50288258; L-Alanine, 3-(methoxyphenylphosphinyl)-N-[(phenylmethoxy)carbonyl]-; (R)-2-Benzyloxycarbonylamino-3-(methoxy-phenyl-phosphinoyl)-propionic acid
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| Activity |
Ki = 880000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis of phosphinic acid transition state analogues for the reaction catalysed by kynureninase. Bioorg Med Chem Lett. 1996 Nov 19;6(22):2643-6. | ||||
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