Binding Site Information of Target
Target General Information | Top | ||||
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Target ID | T12097 | Target Info | |||
Target Name | Melanoma-associated antigen 4 (MAGEA4) | ||||
Synonyms | MAGE4; MAGE-X2 antigen; MAGE-X2; MAGE-41 antigen; MAGE-41; MAGE-4 protein; MAGE-4 antigen; Cancer/testis antigen 1.4; CT1.4 | ||||
Target Type | Clinical trial Target | ||||
Gene Name | MAGEA4 | ||||
Biochemical Class | Melanoma associated antigen | ||||
UniProt ID |
Drug Binding Sites of Target | Top | |||||
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Ligand Name: 2-(2-{2-[2-(2-Methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethanol | Ligand Info | |||||
Structure Description | CRYSTAL STRUCTURE OF HLA-A*0201/MAGE-A4-PEPTIDE COMPLEX | PDB:1I4F | ||||
Method | X-ray diffraction | Resolution | 1.40 Å | Mutation | No | [1] |
PDB Sequence |
GVYDGREHTV
10
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References | Top | ||||
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REF 1 | High-resolution structure of HLA-A*0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene. J Mol Biol. 2001 Jul 27;310(5):1167-76. |
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