Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T12797 | Target Info | |||
| Target Name | Bcl-2-related protein A1 (BCL2A1) | ||||
| Synonyms | Protein GRS; Protein BFL-1; Hemopoietic-specific early response protein; HBPA1; GRS; Bcl2-L-5; Bcl-2-like protein 5; BFL1; BCL2L5 | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | BCL2A1 | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: Hydroxydimethylarsine Oxide | Ligand Info | |||||
| Structure Description | Crystal Structure of Bcl-2-related protein A1 | PDB:5WHI | ||||
| Method | X-ray diffraction | Resolution | 1.69 Å | Mutation | Yes | [1] |
| PDB Sequence |
SEFGYIYRLA
13 QDYLQSVLQI23 PQSGPSKTSR35 VLQNVAFSVQ45 KEVEKNLKSC55 LDNVNVVSVD 65 TARTLFNQVM75 EKEFEDGIIN85 WGRIVTIFAF95 EGILIKKLLR105 QQIAPDVDTY 115 KEISYFVAEF125 IMNNTGEWIR135 QNGGWENGFV145 KKFEPK
|
|||||
|
|
||||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor. Structure. 2018 Jan 2;26(1):153-160.e4. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.