Binding Site Information of Target
Target General Information | Top | ||||
---|---|---|---|---|---|
Target ID | T34318 | Target Info | |||
Target Name | Cathelicidin antimicrobial peptide (CAMP) | ||||
Synonyms | upregulating cAMP; hCAP18; CAP18; CAMP; Antibacterial protein LL37; 18 kDa cationic antimicrobial protein | ||||
Target Type | Successful Target | ||||
Gene Name | CAMP | ||||
Biochemical Class | Cathelicidin family | ||||
UniProt ID |
Drug Binding Sites of Target | Top | |||||
---|---|---|---|---|---|---|
Ligand Name: Lauryl Dimethylamine-N-Oxide | Ligand Info | |||||
Structure Description | The structure of LL-37 crystallized in the presence LDAO | PDB:5NNK | ||||
Method | X-ray diffraction | Resolution | 1.80 Å | Mutation | No | [1] |
PDB Sequence |
LLGDFFRKSK
10 EKIGKEFKRI20 VQRIKDFLRN30 LVPR
|
|||||
|
||||||
Ligand Name: Dodecylphosphocholine | Ligand Info | |||||
Structure Description | The dimeric structure of LL-37 crystallized in DPC | PDB:5NNT | ||||
Method | X-ray diffraction | Resolution | 2.21 Å | Mutation | No | [1] |
PDB Sequence |
LLGDFFRKSK
10 EKIGKEFKRI20 VQRIKDFLRN30 LVPR
|
|||||
|
References | Top | ||||
---|---|---|---|---|---|
REF 1 | Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species. Sci Rep. 2017 Nov 13;7(1):15371. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.