Binding Site Information of Target

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Target General Information
Drug Binding Sites of Target
References
Target General Information  Top
Target ID T57059 Target Info
Target Name E2F transcription factor 1 (E2F1)
Synonyms pRB-binding protein E2F-1; Transcription factor E2F1; Retinoblastoma-binding protein 3; Retinoblastoma-associated protein 1; RBBP3; RBBP-3; RBAP-1; PBR3; E2F-1
Target Type Clinical trial Target
Gene Name E2F1
UniProt ID
E2F1_HUMAN
Drug Binding Sites of Target  Top
Ligand Name: SDMA Ligand Info
Structure Description Crystal structure of human TDRD1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide PDB:5M9N
Method X-ray diffraction Resolution 1.95 Å Mutation No [1]
PDB Sequence
GG
Residue
Distance (Å)
GLY7
1.340
Residue
Distance (Å)
GLY9
1.335
References  Top
REF 1 Crystal structure of human TDRD1 extended Tudor domain in complex with a symmetrically

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