Binding Site Information of Target

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Target General Information
Drug Binding Sites of Target
References
Target General Information  Top
Target ID T67801 Target Info
Target Name Lactotransferrin (LTF)
Synonyms Talalactoferrin; Lactoferrin; LF; Growth-inhibiting protein 12; GIG12
Target Type Clinical trial Target
Gene Name LTF
Biochemical Class Transferrin
UniProt ID
TRFL_HUMAN
Drug Binding Sites of Target  Top
Ligand Name: Lauric acid Ligand Info
Structure Description Structure of C12-LF11 bound to the DPC micelles PDB:2GMC
Method Solution NMR Resolution N.A. Mutation No [1]
PDB Sequence
FQWQRNIRKV
10
R
Residue
Distance (Å)
PHE1
1.655
GLN2
2.147
Residue
Distance (Å)
TRP3
2.075
GLN4
2.165
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References  Top
REF 1 The acyl group as the central element of the structural organization of antimicrobial lipopeptide. J Am Chem Soc. 2007 Feb 7;129(5):1022-3.

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