Binding Site Information of Target
Target General Information | Top | ||||
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Target ID | T85616 | Target Info | |||
Target Name | Thioredoxin (TXN) | ||||
Synonyms | Trx; TRX1; TRDX; Surface-associated sulphydryl protein; Surface associated sulphydryl protein; SASP; ATL-derived factor; ADF | ||||
Target Type | Clinical trial Target | ||||
Gene Name | TXN | ||||
UniProt ID |
Drug Binding Sites of Target | Top | |||||
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Ligand Name: 2-Mercaptoethanesulfonic acid | Ligand Info | |||||
Structure Description | Crystal structures of thioredoxin with mesna at 1.85A resolution | PDB:4POM | ||||
Method | X-ray diffraction | Resolution | 1.85 Å | Mutation | Yes | [1] |
PDB Sequence |
GTMVKQIESK
8 TAFQKALKAA18 GDKLVVVDFS28 ATWCGPCKMI38 KPFFHSLSEK48 YSNVIFLEVD 58 VDDCQDVASE68 CEVKCMPTFQ78 FFKKGQKVGE88 FSGANKKKLE98 ATINKLV |
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Click to View More Binding Site Information of This Target and Ligand Pair |
References | Top | ||||
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REF 1 | BNP7787 Forms Novel Covalent |
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