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Target General Information |
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Target ID |
T57700 |
Target Info
|
Target Name |
Tyrosine-protein kinase Kit (KIT) |
Synonyms |
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; p145 c-kit; Proto-oncogene tyrosine-protein kinase Kit; Proto-oncogene c-Kit; Piebald trait protein; PBT; Mast/stem cell growth factor receptor Kit; CD117 antigen; CD117; C-kit |
Target Type |
Successful Target |
Gene Name |
KIT |
Biochemical Class |
Kinase |
UniProt ID |
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Targeted Antigens of CAR-T Cell Therapy |
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CAR T-Cell Therapy Drug(s) |
CART-117 cells |
Drug Info
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Phase 1 |
Myelodysplastic syndrome |
[1] |
CAR-T cells targeting CD117 |
Drug Info
|
Preclinical |
Acute myeloid leukaemia |
[2] |
References |
Top |
REF 1 |
ClinicalTrials.gov (NCT03291444) CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS
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REF 2 |
ClinicalTrials.gov (NCT03473457) CAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia
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