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Target General Information |
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Target ID |
T86323 |
Target Info
|
Target Name |
Neural cell adhesion molecule 1 (NCAM1) |
Synonyms |
NCAM-1; NCAM; N-CAM-1; MSK39; CD56 |
Target Type |
Clinical trial Target |
Gene Name |
NCAM1 |
UniProt ID |
|
Targeted Antigens of CAR-T Cell Therapy |
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CAR T-Cell Therapy Drug(s) |
CD56 CAR T cells |
Drug Info
|
Phase 1/2 |
Multiple myeloma |
[1] |
CD56-specific gene-engineered T cells |
Drug Info
|
Phase 1/2 |
Acute myeloid leukaemia |
[2] |
CART-56 cells |
Drug Info
|
Phase 1 |
Myelodysplastic syndrome |
[3] |
CAR-T cells targeting CD56 |
Drug Info
|
Clinical trial |
Multiple myeloma |
[4] |
CAR-T cells targeting CD56 |
Drug Info
|
Preclinical |
Acute myeloid leukaemia |
[5] |
References |
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REF 1 |
ClinicalTrials.gov (NCT03271632) Multi-CAR T Cell Therapy in the Treatment of Multiple Myeloma
|
REF 2 |
ClinicalTrials.gov (NCT03222674) Multi-CAR T Cell Therapy for Acute Myeloid Leukemia
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REF 3 |
ClinicalTrials.gov (NCT03291444) CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS
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REF 4 |
ClinicalTrials.gov (NCT03473496) CAR-T Cells Therapy in Relapsed/Refractory Multiple Myeloma
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REF 5 |
ClinicalTrials.gov (NCT03473457) CAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia
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