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Target General Information |
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Target ID |
T93923 |
Target Info
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Target Name |
Co-stimulatory molecule 4-1BB (CD137) |
Synonyms |
Tumor necrosis factor receptor superfamily member 9; T-cell antigen ILA; T-cell antigen 4-1BB homolog; ILA; CDw137; 4-1BB ligand receptor |
Target Type |
Clinical trial Target |
Gene Name |
TNFRSF9 |
Biochemical Class |
Cytokine receptor |
UniProt ID |
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Targeted Antigens of CAR-T Cell Therapy |
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CAR T-Cell Therapy Drug(s) |
CD137 CAR-T Cell |
Drug Info
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Phase 1/2 |
B-cell lymphoma |
[1] |
MG7-CART |
Drug Info
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Phase 1/2 |
Acute myeloid leukaemia |
[2] |
References |
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REF 1 |
ClinicalTrials.gov (NCT02965092) CD19 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With B-cell Malignancies
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REF 2 |
ClinicalTrials.gov (NCT02862704) A Study of MG7 Redirected Autologous T Cells for Advanced MG7 Positive Liver Metastases(MG7-CART)
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