Target Regulator(s) Information (MicroRNA)

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Target General Information
The microRNAs (miRNAs) Regulating This Target
References
Target General Information  Top
Target ID T14306 Target Info
Target Name CASP8-FADD-like regulator (CFLAR)
Synonyms cFLIP; c-FLIP; Usurpin; MRIT; MACHrelated inducer of toxicity; MACH-related inducer of toxicity; Inhibitor of FLICE; IFLICE; I-FLICE; FLAME1; FLAME-1; FADDlike antiapoptotic molecule 1; FADD-like antiapoptotic molecule 1; Cellular FLICElike inhibitory protein; Cellular FLICE-like inhibitory protein; Casper; Caspaselike apoptosis regulatory protein; Caspaseeightrelated protein; Caspase-like apoptosis regulatory protein; Caspase-eight-related protein; Caspase homolog; CLARP; CASP8AP1; CASP8 and FADDlike apoptosis regulator subunit p12; CASP8 and FADDlike apoptosis regulator; CASP8 and FADD-like apoptosis regulator; CASH
Target Type Literature-reported Target
Gene Name CFLAR
Biochemical Class Peptidase
UniProt ID
O15519
The microRNAs (miRNAs) Regulating This Target  Top
miRNA Mature ID hsa-miR-512-3p miRNA Info
miRNA Mature AC
MIMAT0002823
Sequence aagugcugucauagcugagguc
miRNA Species Homo sapiens
Evidence Score (E-score) 1 +
1 Luciferase Reporter Assay [1]
Representative Target(s) Regulated by This miRNA CASP8-FADD-like regulator (CFLAR) Target Info
CFLAR_HUMAN
References  Top
REF 1 Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells. Oncol Rep. 2010 May;23(5):1457-62.

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