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Target General Information |
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Target ID |
T55959 |
Target Info
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Target Name |
Dopamine transporter (DAT) |
Synonyms |
Solute carrier family 6 member 3; Sodium-dependent dopamine transporter; DAT1; DAT; DA transporter |
Target Type |
Successful Target |
Gene Name |
SLC6A3 |
Biochemical Class |
Neurotransmitter:sodium symporter |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-491-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
aguggggaacccuuccaugagg
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miRNA Species |
Homo sapiens |
Evidence Score (E-score) |
1 |
+ |
1 |
GFP Reporter Assay; Luciferase Reporter Assay; Western Blot |
[1] |
Representative Target(s) Regulated by This miRNA |
Apoptosis regulator Bcl-xL (BCL-xL)
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Target Info
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Cellular tumor antigen p53 (TP53)
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Target Info
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References |
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REF 1 |
miR-137 and miR-491 Negatively Regulate Dopamine Transporter Expression and Function in Neural Cells. Neurosci Bull. 2016 Dec;32(6):512-522.
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