Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T10899 Target Info
Target Name Ubiquitin carboxyl-terminal hydrolase 37 (USP37)
Synonyms Ubiquitin-specific-processing protease 37; Ubiquitin thioesterase 37; KIAA1594; Deubiquitinating enzyme 37
Target Type Literature-reported Target
Gene Name USP37
Biochemical Class Peptidase
UniProt ID
UBP37_HUMAN 
Target Interacting Proteins  Top
Ubiquitin related proteins [+] 4 Ubiquitin related proteins +
Other proteins [+] 3 Other proteins +
References  Top
REF 1 Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37. J Biol Chem. 2014 Jan 24;289(4):2415-23.
REF 2 A strategy for modulation of enzymes in the ubiquitin system. Science. 2013 Feb 1;339(6119):590-5.
REF 3 Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25. Sci Rep. 2017 Mar 22;7:45037.
REF 4 Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry. Mol Cell. 2011 May 20;42(4):511-23.
REF 5 The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression. Curr Biol. 2015 Aug 31;25(17):2290-9.
REF 6 Skp1-Cul1-F-box ubiquitin ligase (SCF(TrCP))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry. J Biol Chem. 2012 Nov 9;287(46):39021-9.
REF 7 Defining the human deubiquitinating enzyme interaction landscape. Cell. 2009 Jul 23;138(2):389-403.

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