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| Target General Information |
Top |
| Target ID |
T14834 |
Target Info
|
| Target Name |
Cytosolic phospholipase A2 (GIVA cPLA2) |
| Synonyms |
Phospholipase A2 group IVA; PLA2G4; CPLA2 |
| Target Type |
Clinical trial Target |
| Gene Name |
PLA2G4A |
| Biochemical Class |
Carboxylic ester hydrolase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Annexin A2 (ANXA2) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Protein I; Placental anticoagulant protein IV; PAP-IV; p36; LPC2D; Lipocortin II; Chromobindin-8; Calpactin-1 heavy chain; Calpactin I heavy chain; CAL1H; ANX2L4; ANX2; Annexin-2; Annexin II |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Cytosolic phospholipase A2-p11 interaction controls arachidonic acid release as a function of epithelial cell confluence. Biochem J. 2004 Mar 1;378(Pt 2):307-15.
|
| REF 2 |
Mechanism of regulation of group IVA phospholipase A2 activity by Ser727 phosphorylation. J Biol Chem. 2008 Feb 15;283(7):3960-71.
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