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| Target General Information |
Top |
| Target ID |
T15439 |
Target Info
|
| Target Name |
C5a anaphylatoxin chemotactic receptor (C5AR1) |
| Synonyms |
CD88; C5aR; C5a-R; C5a anaphylatoxin chemotactic receptor 1; C5R1 |
| Target Type |
Successful Target |
| Gene Name |
C5AR1 |
| Biochemical Class |
GPCR rhodopsin |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Guanine nucleotide-binding |
[+] 1 Guanine nucleotide-binding |
+ |
| Interacting Protein Name |
Adenylate cyclase-inhibiting G alpha protein (GNAI2) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Co-localization |
[1] |
| 2 |
Co-purification |
[2] |
| References |
Top |
| REF 1 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
|
| REF 2 |
Stabilization of C5a receptor--G-protein interactions through ligand binding. J Cell Biochem. 1994 Jul;55(3):380-8.
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