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REF 1 |
c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination. J Immunol. 2002 Oct 1;169(7):3793-800.
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REF 2 |
Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1. Science. 1997 Oct 3;278(5335):124-8.
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REF 3 |
Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45. Blood Cells Mol Dis. 2006 Mar-Apr;36(2):308-14.
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REF 4 |
Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells. J Biol Chem. 1996 Oct 25;271(43):27130-7.
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REF 5 |
The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase. J Biol Chem. 1995 Aug 11;270(32):19141-50.
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REF 6 |
Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase. J Biol Chem. 1997 Jan 10;272(2):739-45.
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REF 7 |
A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytes. Exp Cell Res. 2003 Sep 10;289(1):184-94.
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REF 8 |
Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases. J Biol Chem. 1998 Apr 10;273(15):8867-74.
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REF 9 |
Biochemical basis for the requirement of kinase activity for Cbl-dependent ubiquitinylation and degradation of a target tyrosine kinase. J Biol Chem. 2004 Aug 20;279(34):36132-41.
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REF 10 |
Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation. J Biol Chem. 2004 Aug 27;279(35):36259-67.
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REF 11 |
Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl. FEBS Lett. 2004 Nov 19;577(3):555-62.
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REF 12 |
The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6439-44.
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REF 13 |
Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G. J Biol Chem. 1996 Apr 5;271(14):8435-42.
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REF 14 |
Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins. J Biol Chem. 1996 Jun 14;271(24):14554-9.
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REF 15 |
Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways. J Biol Chem. 1995 Jun 16;270(24):14347-51.
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REF 16 |
Activation of NMDA receptors and L-type voltage-gated calcium channels mediates enhanced formation of Fyn-PSD95-NR2A complex after transient brain ischemia. Brain Res. 2002 Nov 15;955(1-2):123-32.
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REF 17 |
The effect of transient global ischemia on the interaction of Src and Fyn with the N-methyl-D-aspartate receptor and postsynaptic densities: possible involvement of Src homology 2 domains. J Cereb Blood Flow Metab. 1999 Aug;19(8):880-8.
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REF 18 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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REF 19 |
Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN. EMBO Rep. 2006 Oct;7(10):1023-9.
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REF 20 |
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell. 2012 Aug 31;150(5):987-1001.
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REF 21 |
Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. J Exp Med. 1997 Apr 7;185(7):1253-9.
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REF 22 |
Molecular alterations of the Fyn-complex occur as late events of human T cell activation. Eur J Immunol. 1999 Apr;29(4):1175-87.
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REF 23 |
An acidic extracellular pH disrupts adherens junctions in HepG2 cells by Src kinases-dependent modification of E-cadherin. J Cell Biochem. 2009 Nov 1;108(4):851-9.
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REF 24 |
Identification of novel human WW domain-containing proteins by cloning of ligand targets. J Biol Chem. 1997 Jun 6;272(23):14611-6.
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REF 25 |
Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin. J Neurochem. 2003 Jan;84(2):253-65.
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REF 26 |
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases. J Biol Chem. 2001 May 18;276(20):17199-205.
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REF 27 |
Epidermal growth factor stimulates RSK2 activation through activation of the MEK/ERK pathway and src-dependent tyrosine phosphorylation of RSK2 at Tyr-529. J Biol Chem. 2008 Feb 22;283(8):4652-7.
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REF 28 |
Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau. J Neurosci. 2002 Feb 1;22(3):698-707.
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REF 29 |
Disease-related modifications in tau affect the interaction between Fyn and Tau. J Biol Chem. 2005 Oct 21;280(42):35119-25.
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REF 30 |
T cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T). J Exp Med. 1993 Dec 1;178(6):2107-13.
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REF 31 |
Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130. J Biol Chem. 1998 Oct 2;273(40):25789-95.
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REF 32 |
Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7493-8.
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REF 33 |
Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. PLoS One. 2012;7(6):e38540.
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REF 34 |
UCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drug. Oncogene. 2002 Mar 27;21(13):2037-50.
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REF 35 |
SKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activation. J Biol Chem. 2002 Oct 25;277(43):40420-7.
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REF 36 |
Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes. J Biol Chem. 1997 Jun 27;272(26):16077-80.
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REF 37 |
Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases. Curr Biol. 1996 Aug 1;6(8):981-8.
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REF 38 |
Sustained activation of N-WASP through phosphorylation is essential for neurite extension. Dev Cell. 2002 Nov;3(5):645-58.
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REF 39 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
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REF 40 |
Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. BMC Immunol. 2009 Oct 6;10:53.
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REF 41 |
Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor. FEBS Lett. 2001 Dec 7;509(2):255-62.
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REF 42 |
Defective thymocyte maturation by transgenic expression of a truncated form of the T lymphocyte adapter molecule and Fyn substrate, Sin. J Immunol. 2002 Dec 15;169(12):6900-9.
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REF 43 |
A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.
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REF 44 |
p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction. Mol Cell Biol. 2003 Apr;23(7):2287-97.
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REF 45 |
Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho. J Cell Biol. 2003 Jul 7;162(1):99-111.
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REF 46 |
RA70 is a src kinase-associated protein expressed ubiquitously. Biochem Biophys Res Commun. 1998 Nov 27;252(3):738-42.
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REF 47 |
Identification and characterization of a novel Pyk2/related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation. J Biol Chem. 2003 Oct 24;278(43):42225-33.
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REF 48 |
TOM1L is involved in a novel signaling pathway important for the IL-2 production in Jurkat T cells stimulated by CD3/CD28 co-ligation. Mediators Inflamm. 2009;2009:416298.
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REF 49 |
'Srcasm: a novel Src activating and signaling molecule. J Biol Chem. 2002 Jan 25;277(4):2812-22.
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REF 50 |
Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells. J Biol Chem. 1998 Nov 27;273(48):31932-8.
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REF 51 |
Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte. J Biol Chem. 2001 Jun 15;276(24):20849-57.
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