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Target General Information |
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Target ID |
T20221 |
Target Info
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Target Name |
Lymphotoxin-beta (LTB) |
Synonyms |
Tumor necrosis factor ligand superfamily member 3; Tumor necrosis factor C; TNF-C; LTB; LT-beta |
Target Type |
Literature-reported Target |
Gene Name |
LTB |
Biochemical Class |
Cytokine: tumor necrosis factor |
UniProt ID |
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Target Interacting Proteins |
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Other proteins |
[+] 1 Other proteins |
+ |
Interacting Target Name |
Lymphotoxin-alpha (LTA) |
Clinical trial Target |
Interacting Protein Info
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UniProt ID |
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Synonyms |
Tumor necrosis factor ligand superfamily member 1; TNFSF1; TNF-beta; TNFB; LT-alpha |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[1] |
2 |
Reconstituted Complex |
[2] |
References |
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REF 1 |
Characterization of surface lymphotoxin forms. Use of specific monoclonal antibodies and soluble receptors. J Immunol. 1995 Jan 1;154(1):33-46.
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REF 2 |
The lymphotoxin-alpha (LTalpha) subunit is essential for the assembly, but not for the receptor specificity, of the membrane-anchored LTalpha1beta2 heterotrimeric ligand. J Biol Chem. 1997 Aug 1;272(31):19451-6.
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