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| Target General Information |
Top |
| Target ID |
T36581 |
Target Info
|
| Target Name |
MAPK-activated protein kinase 3 (MAPKAPK3) |
| Synonyms |
MAPKAPK3 |
| Target Type |
Literature-reported Target |
| Gene Name |
MAPKAPK3 |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 2 Kinases |
+ |
| Interacting Target Name |
Stress-activated protein kinase 2a (p38 alpha) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
SAPK2A; P38 Mitogen-activatedprotein kinase alpha; P38 mitogen activatedprotein kinase; MXI2; Mitogen-activated protein kinase p38 alpha; Mitogen-activated protein kinase 14; MAX-interacting protein 2; MAPK 14; MAP kinase p38alpha; MAP kinase p38 alpha; MAP kinase MXI2; MAP kinase 14; Cytokine suppressive anti-inflammatory drug-binding protein; Cytokine suppressive anti-inflammatory drug binding protein; CSPB1; CSBP2; CSBP1; CSBP; CSAID-binding protein; CSAID binding protein; CRK1 |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Biochemical Activity |
[2] |
| 3 |
Co-localization |
[3] |
| Interacting Target Name |
Stress-activated protein kinase 2b (p38 beta) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Stress-activated protein kinase-2; SAPK2b; SAPK2; PRKM11; P38b; P38-2; P38 Mitogen-activated protein kinase beta; Mitogen-activated protein kinase p38 beta; Mitogen-activated protein kinase 11; MAPK 11; MAP kinase p38 beta; MAP kinase 11 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[4] |
| 2 |
Yeast two hybrid |
[5] |
| References |
Top |
| REF 1 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
|
| REF 2 |
MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes. Blood. 2004 Dec 15;104(13):4260-8.
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| REF 3 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
|
| REF 4 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep. 2013 Apr 25;3(4):1306-20.
|
| REF 5 |
Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536.
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