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| Target General Information |
Top |
| Target ID |
T44141 |
Target Info
|
| Target Name |
Angiopoietin-1 (ANGPT1) |
| Synonyms |
Angiopoietin1; ANGPT1; ANG1; ANG-1 |
| Target Type |
Clinical trial Target |
| Gene Name |
ANGPT1 |
| Biochemical Class |
Fibrinogen protein |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
Angiopoietin 1 receptor (TEK) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
VMCM1; VMCM; Tyrosine-protein kinase receptor TIE-2; Tyrosine-protein kinase receptor TEK; Tyrosine kinase with Ig and EGF homology domains-2; Tunica interna endothelial cell kinase; TIE2; P140 TEK; hTIE2; Endothelial tyrosine kinase; Endothelial Cell-Specific Receptor TIE-2; CD202b antigen; CD202b |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[1] |
| References |
Top |
| REF 1 |
Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats. J Biol Chem. 2003 Jan 17;278(3):1721-7.
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