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| Target General Information |
Top |
| Target ID |
T46000 |
Target Info
|
| Target Name |
MEK kinase kinase 3 (MAP4K3) |
| Synonyms |
RAB8IPL1; Mitogen-activated protein kinase kinase kinase kinase 3; MEKKK 3; MAPK/ERK kinase kinase kinase 3; Germinal center kinase-related protein kinase; GLK |
| Target Type |
Literature-reported Target |
| Gene Name |
MAP4K3 |
| Biochemical Class |
Kinase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Adapter proteins |
[+] 1 Adapter proteins |
+ |
| Interacting Protein Name |
Growth factor receptor-bound protein 2 (GRB2) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
SH2/SH3 adapter GRB2; Protein Ash; Growth factor receptor-bound protein 2; ASH; Adapter protein GRB2 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Yeast two hybrid |
[2] |
| References |
Top |
| REF 1 |
Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor. Nat Biotechnol. 2011 Jun 26;29(7):653-8.
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| REF 2 |
A human MAP kinase interactome. Nat Methods. 2010 Oct;7(10):801-5.
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