Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T48881 Target Info
Target Name Herpes virus entry mediator ligand (CD258)
Synonyms UNQ391/PRO726; Tumor necrosis factor ligand superfamily member 14, soluble form; Tumor necrosis factor ligand superfamily member 14; LIGHT; Herpesvirus entry mediator ligand; HVEML; HVEM-L
Target Type Clinical trial Target
Gene Name TNFSF14
Biochemical Class Cytokine: tumor necrosis factor
UniProt ID
TNF14_HUMAN 
Target Interacting Proteins  Top
Other proteins [+] 2 Other proteins +
Interacting Target Name Herpesvirus entry mediator (CD270) Literature-reported Target Interacting Protein Info
UniProt ID
TNR14_HUMAN 
Synonyms UNQ329/PRO509; Tumor necrosis factor receptor-like 2; Tumor necrosis factor receptor superfamily member 14; TR2; HVEM; HveA; Herpesvirus entry mediator A; Herpes virus entry mediator A
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Reconstituted Complex [2]
Interacting Protein Name Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) Interacting Protein Interacting Protein Info
UniProt ID
TNF6B_HUMAN 
Synonyms DCR3; DJ583P15.1.1; M68; M68E; TR6
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Reconstituted Complex [2]
References  Top
REF 1 A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis. J Biol Chem. 1999 May 14;274(20):13733-6.
REF 2 Modulation of T-cell responses to alloantigens by TR6/DcR3. J Clin Invest. 2001 Jun;107(11):1459-68.

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