Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T49888 Target Info
Target Name IKK complex-associated protein (IKBKAP)
Synonyms IkappaB kinase complexassociated protein; IkappaB kinase complex-associated protein; IKK complexassociated protein; IKAP; Elongator complex protein 1; ELP1
Target Type Literature-reported Target
Gene Name IKBKAP
UniProt ID
ELP1_HUMAN 
Target Interacting Proteins  Top
Acyltransferases [+] 2 Acyltransferases +
Beta-transducin repeats [+] 1 Beta-transducin repeats +
References  Top
REF 1 IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration. J Cell Sci. 2008 Mar 15;121(Pt 6):854-64.
REF 2 Purification and characterization of the human elongator complex. J Biol Chem. 2002 Jan 25;277(4):3047-52.
REF 3 The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents. PLoS Genet. 2009 Oct;5(10):e1000684.
REF 4 Dimerization of elongator protein 1 is essential for Elongator complex assembly. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10697-702.
REF 5 Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
REF 6 A census of human soluble protein complexes. Cell. 2012 Aug 31;150(5):1068-81.

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