Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T52297 Target Info
Target Name Oxysterols receptor LXR-alpha (NR1H3)
Synonyms Nuclear receptor subfamily 1 group H member 3; Nuclear receptor LXRalpha; Nuclear orphan receptor LXR-alpha; Liver X receptor alpha; LXRalpha; LXRA
Target Type Patented-recorded Target
Gene Name NR1H3
Biochemical Class Nuclear hormone receptor
UniProt ID
NR1H3_HUMAN 
Target Interacting Proteins  Top
Nuclear hormone receptors [+] 3 Nuclear hormone receptors +
References  Top
REF 1 Small heterodimer partner SHP mediates liver X receptor (LXR)-dependent suppression of inflammatory signaling by promoting LXR SUMOylation specifically in astrocytes. Sci Signal. 2016 Aug 2;9(439):ra78.
REF 2 The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity. Mol Endocrinol. 2002 Sep;16(9):2065-76.
REF 3 Next-generation sequencing to generate interactome datasets. Nat Methods. 2011 Jun;8(6):478-80.
REF 4 Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Mol Cell Proteomics. 2005 Feb;4(2):205-13.
REF 5 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell. 2016 Feb 11;164(4):805-17.

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