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| Target General Information |
Top |
| Target ID |
T60636 |
Target Info
|
| Target Name |
Alpha-ketoglutarate dehydrogenase (OGDH) |
| Synonyms |
OGDC-E1; 2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase complex component E1 |
| Target Type |
Clinical trial Target |
| Gene Name |
OGDH |
| Biochemical Class |
Aldehyde/oxo donor oxidoreductase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Acyltransferases |
[+] 1 Acyltransferases |
+ |
| Interacting Protein Name |
Dihydrolipoamide S-succinyltransferase (DLST) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
DLTS |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Co-fractionation |
[1] |
| 2 |
Co-fractionation |
[2] |
| 3 |
Reconstituted Complex |
[3] |
| References |
Top |
| REF 1 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
|
| REF 2 |
A census of human soluble protein complexes. Cell. 2012 Aug 31;150(5):1068-81.
|
| REF 3 |
Subunit interactions in the mammalian alpha-ketoglutarate dehydrogenase complex. Evidence for direct association of the alpha-ketoglutarate dehydrogenase and dihydrolipoamide dehydrogenase components. J Biol Chem. 1998 Sep 11;273(37):24158-64.
|
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