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Target General Information |
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Target ID |
T61657 |
Target Info
|
Target Name |
Retinoic acid receptor beta (RARB) |
Synonyms |
RAR-epsilon; RAR-beta; Nuclear receptor subfamily 1 group B member 2; NR1B2; HBV-activated protein; HAP |
Target Type |
Successful Target |
Gene Name |
RARB |
Biochemical Class |
Nuclear hormone receptor |
UniProt ID |
|
Target Interacting Proteins |
Top |
Nuclear hormone receptors |
[+] 3 Nuclear hormone receptors |
+ |
Interacting Target Name |
Retinoic acid receptor RXR-gamma (RXRG) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Retinoid X receptor gamma; Nuclear receptor subfamily 2 group B member 3; NR2B3 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Yeast two hybrid |
[1] |
2 |
Yeast two hybrid |
[2] |
3 |
Yeast two hybrid |
[3] |
Interacting Target Name |
Retinoic acid receptor RXR-beta (RXRB) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Retinoid X receptor beta; Nuclear receptor subfamily 2 group B member 2; NR2B2 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Yeast two hybrid |
[2] |
2 |
Yeast two hybrid |
[3] |
Interacting Target Name |
Retinoic acid receptor alpha (RARA) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
RAR-alpha; RAR alpha; Nuclear receptor subfamily 1 group B member 1; NR1B1 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[4] |
2 |
Co-localization |
[5] |
References |
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REF 1 |
An atlas of combinatorial transcriptional regulation in mouse and man. Cell. 2010 Mar 5;140(5):744-52.
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REF 2 |
A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.
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REF 3 |
Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Mol Cell Proteomics. 2005 Feb;4(2):205-13.
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REF 4 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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REF 5 |
Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma. PLoS One. 2011;6(10):e26236.
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