Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T61792 Target Info
Target Name Multidrug resistance-associated protein 2 (ABCC2)
Synonyms MRP2; Canalicular multispecific organic anion transporter 1; Canalicular multidrug resistance protein; CMRP; CMOAT1; CMOAT; ATP-binding cassette, sub-family C, member 2; ATP-binding cassette sub-family C member 2
Target Type Literature-reported Target
Gene Name ABCC2
Biochemical Class ABC transporter
UniProt ID
MRP2_HUMAN 
Target Interacting Proteins  Top
Other proteins [+] 1 Other proteins +
Interacting Target Name PDZ domain containing-protein (PDZK1) Literature-reported Target Interacting Protein Info
UniProt ID
NHRF3_HUMAN 
Synonyms Sodium-hydrogen exchanger regulatory factor 3; PDZD1; PDZ domain-containing protein 1; NHERF-3; NHERF3; NaPi-Cap1; Na/Pi cotransporter C-terminal-associated protein 1; Na(+)/H(+) exchanger regulatory factor 3; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; Multi-PDZ domain containing adaptor protein; CFTR-associated protein of 70 kDa; CAP70
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-localization [1]
2 Yeast two hybrid [2]
References  Top
REF 1 ATP-binding cassette transporter isoform C2 localizes to the apical plasma membrane via interactions with scaffolding protein. J Biochem. 2011 Feb;149(2):177-89.
REF 2 PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein. Lab Invest. 1999 Sep;79(9):1161-70.

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