| References |
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| REF 1 |
The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Elife. 2018 May 30;7. pii: e31879.
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| REF 2 |
RNA helicase A interacts with RISC in human cells and functions in RISC loading. Mol Cell. 2007 May 25;26(4):523-37.
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| REF 3 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
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| REF 4 |
HEXIM1 down-regulates hypoxia-inducible factor-1 protein stability. Biochem J. 2013 Dec 1;456(2):195-204.
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| REF 5 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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| REF 6 |
The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes. EMBO Rep. 2008 Jun;9(6):569-75.
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| REF 7 |
The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1. Oncogene. 2005 Aug 25;24(36):5576-88.
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| REF 8 |
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol Cell. 2005 Aug 19;19(4):535-45.
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| REF 9 |
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E15-24.
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| REF 10 |
Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. Mol Cell. 2003 Oct;12(4):971-82.
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| REF 11 |
MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner. Mol Cell Biol. 2003 Jul;23(14):4859-69.
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| REF 12 |
A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb. Mol Cell Biol. 2004 Jun;24(12):5094-105.
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| REF 13 |
Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor. EMBO J. 2004 Jul 7;23(13):2608-19.
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| REF 14 |
Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat. J Biol Chem. 2005 Jul 1;280(26):24968-77.
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| REF 15 |
Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription. J Biol Chem. 2005 Apr 22;280(16):16368-76.
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| REF 16 |
Identification of HEXIM1 as a positive regulator of p53. J Biol Chem. 2012 Oct 19;287(43):36443-54.
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| REF 17 |
A high-throughput approach for measuring temporal changes in the interactome. Nat Methods. 2012 Sep;9(9):907-9.
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