Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T75210 Target Info
Target Name LDL receptor related protein-2 (LRP-2)
Synonyms Megalin; Lowdensity lipoprotein receptorrelated protein 2; Low-density lipoprotein receptor-related protein 2; Gp330; Glycoprotein 330
Target Type Literature-reported Target
Gene Name LRP2
Biochemical Class Low density lipoprotein receptor
UniProt ID
LRP2_HUMAN 
Target Interacting Proteins  Top
Microtubule-associated [+] 1 Microtubule-associated +
Other proteins [+] 1 Other proteins +
References  Top
REF 1 Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins. Biochem J. 2003 Jul 15;373(Pt 2):381-91.
REF 2 Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. J Biol Chem. 2000 Aug 18;275(33):25616-24.
REF 3 GAIP, GIPC and Galphai3 are concentrated in endocytic compartments of proximal tubule cells: putative role in regulating megalin's function. J Am Soc Nephrol. 2002 Apr;13(4):918-27.
REF 4 Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule. J Cell Sci. 2003 Feb 1;116(Pt 3):453-61.

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