| References |
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| REF 1 |
FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes. J Biol Chem. 2003 Jun 20;278(25):22600-8.
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| REF 2 |
FKBP12 binding modulates ryanodine receptor channel gating. J Biol Chem. 2001 May 18;276(20):16931-5.
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| REF 3 |
In smooth muscle, FK506-binding protein modulates IP3 receptor-evoked Ca2+ release by mTOR and calcineurin. J Cell Sci. 2005 Dec 1;118(Pt 23):5443-51.
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| REF 4 |
FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain. J Biol Chem. 1997 Oct 31;272(44):27582-8.
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| REF 5 |
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol. 2004 Nov;6(11):1122-8.
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| REF 6 |
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol. 2004 Jul 27;14(14):1296-302.
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| REF 7 |
Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. Science. 1996 Jul 12;273(5272):239-42.
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| REF 8 |
Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. Acta Crystallogr D Biol Crystallogr. 1999 Apr;55(Pt 4):736-44.
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| REF 9 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
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| REF 10 |
Dual-color click beetle luciferase heteroprotein fragment complementation assays. Chem Biol. 2010 Sep 24;17(9):1018-29.
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| REF 11 |
Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells. J Biol Chem. 1995 Jan 13;270(2):815-22.
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| REF 12 |
Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12288-93.
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| REF 13 |
Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12. Science. 1994 Jul 29;265(5172):674-6.
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| REF 14 |
Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Mol Cell Biol. 1995 Jul;15(7):3479-86.
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| REF 15 |
FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor. J Mol Endocrinol. 2006 Jun;36(3):569-79.
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| REF 16 |
Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells. Nat Methods. 2005 Jun;2(6):427-33.
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| REF 17 |
FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin. J Biol Chem. 1996 Dec 20;271(51):32923-9.
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| REF 18 |
Mutation of FKBP associated protein 48 (FAP48) at proline 219 disrupts the interaction with FKBP12 and FKBP52. Regul Pept. 2001 Mar 2;97(2-3):147-52.
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