| References |
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| REF 1 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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| REF 2 |
Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis. J Biol Chem. 2003 Jun 20;278(25):23130-40.
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| REF 3 |
The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9. J Biol Chem. 2005 Jan 7;280(1):174-82.
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| REF 4 |
Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein. J Biol Chem. 2003 Dec 26;278(52):52660-72.
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| REF 5 |
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature. 2001 Mar 1;410(6824):112-6.
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| REF 6 |
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell. 2000 Jul 7;102(1):43-53.
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| REF 7 |
Monomerization of cytosolic mature smac attenuates interaction with IAPs and potentiation of caspase activation. PLoS One. 2010 Oct 1;5(10). pii: e13094.
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| REF 8 |
Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ. J Biol Chem. 2002 Nov 15;277(46):44236-43.
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| REF 9 |
Knockdown of miR-182 promotes apoptosis via regulating RIP1 deubiquitination in TNF--treated triple-negative breast cancer cells. Tumour Biol. 2016 Oct;37(10):13733-13742.
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| REF 10 |
Survivin interacts with Smac/DIABLO in ovarian carcinoma cells but is redundant in Smac-mediated apoptosis. Exp Cell Res. 2005 Jan 1;302(1):69-82.
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| REF 11 |
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function. Nat Cell Biol. 2004 Sep;6(9):849-60.
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| REF 12 |
Structural basis of IAP recognition by Smac/DIABLO. Nature. 2000 Dec 21-28;408(6815):1008-12.
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| REF 13 |
The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9. Acta Crystallogr D Biol Crystallogr. 2009 Jan;65(Pt 1):58-66.
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| REF 14 |
Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac. J Biol Chem. 2003 Dec 5;278(49):49517-22.
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| REF 15 |
Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases. J Biol Chem. 2006 Jan 13;281(2):1080-90.
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| REF 16 |
The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation. J Biol Chem. 2014 Sep 12;289(37):25721-36.
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| REF 17 |
Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells. J Biol Chem. 2004 Apr 23;279(17):16963-70.
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| REF 18 |
Livin modulates the apoptotic effects of vesicular stomatotitis virus in lung adenocarcinoma. Int J Oncol. 2015 Nov;47(5):1775-82.
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| REF 19 |
Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway. Cell Death Differ. 2006 Dec;13(12):2079-88.
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| REF 20 |
Mechanism of XIAP-mediated inhibition of caspase-9. Mol Cell. 2003 Feb;11(2):519-27.
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| REF 21 |
Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. J Biol Chem. 2003 Mar 21;278(12):10055-60.
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| REF 22 |
A single amino acid change (Asp 53 --> Ala53) converts Survivin from anti-apoptotic to pro-apoptotic. Mol Biol Cell. 2004 Mar;15(3):1287-96.
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| REF 23 |
Survivin monomer plays an essential role in apoptosis regulation. J Biol Chem. 2011 Jul 1;286(26):23296-307.
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| REF 24 |
Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex. Clin Cancer Res. 2013 Feb 1;19(3):631-42.
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