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| Target General Information |
Top |
| Target ID |
T78567 |
Target Info
|
| Target Name |
Oncostatin-M-specific receptor beta (OSMR) |
| Synonyms |
Oncostatin-M-specific receptor subunit beta; OSMRB; Interleukin-31 receptor subunit beta; IL-31RB; IL-31R-beta; IL-31R subunit beta; IL-31 receptor subunit beta |
| Target Type |
Literature-reported Target |
| Gene Name |
OSMR |
| Biochemical Class |
Cytokine receptor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
Erbb2 tyrosine kinase receptor (HER2) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Tyrosine kinase-type cell surface receptor HER2; Tyrosine kinase receptor ErbB2; Receptor tyrosine-protein kinase erbB-2; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; P185erbB2; NGL; NEU proto-oncogene; NEU; MLN19; MLN 19; Metastatic lymph node gene 19 protein; HER2/neu; HER2 (erbB2/neu); HER-2; Erb2; Epidermal growth factor receptor 2; C-erbB-2 oncoprotein; C-erbB-2; CD340 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Co-localization |
[2] |
| References |
Top |
| REF 1 |
An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells. Oncogene. 2002 Jan 17;21(3):460-74.
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| REF 2 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
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