Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T89793 Target Info
Target Name Transducin beta-like 1X-related protein 1 (TBL1XR1)
Synonyms Transducin betalike 1Xrelated protein 1; TBLR1; TBL1related protein 1; TBL1-related protein 1; Nuclear receptor corepressor/HDAC3 complexsubunit TBLR1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; IRA1; Fboxlike/WD repeatcontaining protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1XR1
Target Type Literature-reported Target
Gene Name TBL1XR1
UniProt ID
TBL1R_HUMAN 
Target Interacting Proteins  Top
Carbon-nitrogen hydrolases [+] 2 Carbon-nitrogen hydrolases +
Transcription regulators [+] 1 Transcription regulators +
References  Top
REF 1 Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol. 2011 Mar;29(3):255-65.
REF 2 Function of multiple Lis-Homology domain/WD-40 repeat-containing proteins in feed-forward transcriptional repression by silencing mediator for retinoic and thyroid receptor/nuclear receptor corepressor complexes. Mol Endocrinol. 2008 May;22(5):1093-104.
REF 3 The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations in TNFAIP3 followed by mutations in TBL1XR1 and CREBBP. Oncotarget. 2017 Mar 7;8(10):17038-17049.
REF 4 Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation. Mol Cell Proteomics. 2011 Feb;10(2):M110.004317.
REF 5 Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1. EMBO J. 2003 Mar 17;22(6):1336-46.

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