| References |
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| REF 1 |
Association between Presenilin-1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTR neurotrophin receptor. J Neurochem. 2009 Jan;108(1):216-30.
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| REF 2 |
TRAF6 stimulates the tumor-promoting effects of TGF type I receptor through polyubiquitination and activation of presenilin 1. Sci Signal. 2014 Jan 7;7(307):ra2.
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| REF 3 |
APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes. J Biol Chem. 2003 Feb 28;278(9):7374-80.
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| REF 4 |
Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity. Neurobiol Dis. 2004 Nov;17(2):260-72.
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| REF 5 |
Interactome mapping suggests new mechanistic details underlying Alzheimer's disease. Genome Res. 2011 Mar;21(3):364-76.
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| REF 6 |
Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates. Neurobiol Dis. 2003 Nov;14(2):194-204.
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| REF 7 |
Active gamma-secretase complexes contain only one of each component. J Biol Chem. 2007 Nov 23;282(47):33985-93.
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| REF 8 |
Direct association of presenilin-1 with beta-catenin. FEBS Lett. 1998 Aug 14;433(1-2):73-7.
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| REF 9 |
A structural switch of presenilin 1 by glycogen synthase kinase 3beta-mediated phosphorylation regulates the interaction with beta-catenin and its nuclear signaling. J Biol Chem. 2007 May 11;282(19):14083-93.
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