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Target General Information |
Top |
Target ID |
T97897 |
Target Info
|
Target Name |
Lipid droplet-associated protein (PLIN1) |
Synonyms |
PLIN1; PERI |
Target Type |
Literature-reported Target |
Gene Name |
PLIN1 |
UniProt ID |
|
Target Interacting Proteins |
Top |
Ester hydrolases |
[+] 1 Ester hydrolases |
+ |
Interacting Target Name |
Hormone sensitive lipase (LIPE) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
HSL; Hormone-sensitive lipase |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[1] |
2 |
Fluorescence Resonance Energy Transfer |
[2] |
3 |
Protein-Fragment Complementation Assay |
[2] |
References |
Top |
REF 1 |
Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins. J Biol Chem. 2009 Nov 13;284(46):32116-25.
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REF 2 |
Analysis of lipolytic protein trafficking and interactions in adipocytes. J Biol Chem. 2007 Feb 23;282(8):5726-35.
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