| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T14263 | ||||
| Target Name | Phospholipase D (PLD) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | Afimoxifene | Drug Info | IC50 = 44 nM | [1] | |
| HALOPEMIDE | Drug Info | IC50 = 6500 nM | [1] | ||
| References | |||||
| REF 1 | Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol. 2009 Feb;5(2):108-17. | ||||
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