Target Validation Information
TTD ID T19579
Target Name Interleukin 2 receptor beta (IL2RB)
Type of Target
Clinical trial
Action against Disease Model Medusa IL-2 Drug Info The potency of IL-2 is EC50 = 20.2+/-1.3 and 22.0+/-1.3 u/ml in Stimulation of natural killer activity in peripheral blood lymphocytes of healthy donors and melanoma patients respectively [1]
References
REF 1 Stimulation of natural killer activity in peripheral blood lymphocytes of healthy donors and melanoma patients in vitro: synergism between interleukin (IL)-12 and IL-15 or IL-12 and IL-2. Naunyn Schmiedebergs Arch Pharmacol. 1998 Sep;358(3):382-9.

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