Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T19579 | ||||
Target Name | Interleukin 2 receptor beta (IL2RB) | ||||
Type of Target |
Clinical trial |
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Action against Disease Model | Medusa IL-2 | Drug Info | The potency of IL-2 is EC50 = 20.2+/-1.3 and 22.0+/-1.3 u/ml in Stimulation of natural killer activity in peripheral blood lymphocytes of healthy donors and melanoma patients respectively | [1] | |
References | |||||
REF 1 | Stimulation of natural killer activity in peripheral blood lymphocytes of healthy donors and melanoma patients in vitro: synergism between interleukin (IL)-12 and IL-15 or IL-12 and IL-2. Naunyn Schmiedebergs Arch Pharmacol. 1998 Sep;358(3):382-9. | ||||
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