Target Validation Information
TTD ID	T21507
Target Name	Fatty acid-binding protein 5 (FABP5)
Type of Target	Patented-recorded
Drug Potency against Target	2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid	Drug Info	Ki = 3 nM	[2]
	2-(Carbazole-9-sulfonyl)-benzoic acid	Drug Info	IC50 = 17000 nM	[1]
	4-Carbazol-9-yl-butyric acid	Drug Info	IC50 = 6700 nM	[1]
	5-Carbazol-9-yl-pentanoic acid	Drug Info	IC50 = 3000 nM	[1]
	BMS-480404	Drug Info	Ki = 33 nM	[2]
	Hexadecanoic acid	Drug Info	IC50 = 1200 nM	[1]
References
REF 1	Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4445-8.
REF 2	NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein. J Med Chem. 2006 Aug 10;49(16):5013-7.

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