| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T40785 | ||||
| Target Name | Fungal Papulacandin B resistance protein 1 (Fung FKS1) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | ACULEACIN A | Drug Info | IC50 = 8000 nM | [1] | |
| L-692289 | Drug Info | IC50 = 70 nM | |||
| References | |||||
| REF 1 | Synthesis, anti-fungal and 1,3--D-glucan synthase inhibitory activities of caffeic and quinic acid derivatives. Bioorg Med Chem. 2010 Oct 1;18(19):7009-14. | ||||
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