Target Validation Information
TTD ID T41201
Target Name Dehydropeptidase I (DPEP1)
Type of Target
Successful
Drug Potency against Target Cilastatin Drug Info IC50 = 100 nM [1]
References
REF 1 The renal membrane dipeptidase (dehydropeptidase I) inhibitor, cilastatin, inhibits the bacterial metallo-beta-lactamase enzyme CphA. Antimicrob Agents Chemother. 1995 Jul;39(7):1629-31.

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