| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T43721 | ||||
| Target Name | Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | GLYCYRRHIZIN | Drug Info | IC50 = 1 nM | [1] | |
| References | |||||
| REF 1 | 4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabeti... Bioorg Med Chem Lett. 2009 Aug 1;19(15):4455-8. | ||||
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