Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T44515 | ||||
Target Name | Mycobacterium Nicotinate-nucleotide pyrophosphorylase (MycB nadC) | ||||
Type of Target |
Literature-reported |
||||
Drug Potency against Target | GMX1777 | Drug Info | IC50 = 25 nM | [1] | |
References | |||||
REF 1 | The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-... Mol Cell Biol. 2009 Nov;29(21):5872-88. | ||||
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