Target Validation Information
TTD ID T44515
Target Name Mycobacterium Nicotinate-nucleotide pyrophosphorylase (MycB nadC)
Type of Target
Literature-reported
Drug Potency against Target GMX1777 Drug Info IC50 = 25 nM [1]
References
REF 1 The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-... Mol Cell Biol. 2009 Nov;29(21):5872-88.

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