Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T46937 | ||||
Target Name | P2Y purinoceptor 12 (P2RY12) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | PSB-0702 | Drug Info | Ki = 21 nM | [1] | |
PSB-0739 | Drug Info | Ki = 24.9 nM | [1] | ||
References | |||||
REF 1 | High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. J Med Chem. 2009 Jun 25;52(12):3784-93. | ||||
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