| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T58716 | ||||
| Target Name | Sphingomyelin phosphodiesterase 4 (SMPD4) | ||||
| Type of Target |
Discontinued |
||||
| Action against Disease Model | ND1251 | Drug Info | DE4 inhibitor ND1251 (Neuro3D) has shown significant antidepressant activity in the mouse and rat | [1] | |
| References | |||||
| REF 1 | Keynote review: phosphodiesterase-4 as a therapeutic target. Drug Discov Today. 2005 Nov 15;10(22):1503-19. | ||||
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