| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T65116 | ||||
| Target Name | Ecto-5'-nucleotidase (CD73) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | Acid blue 25 | Drug Info | Ki = 15200 nM | [1] | |
| PSB-0952 | Drug Info | Ki = 260 nM | [1] | ||
| PSB-0963 | Drug Info | Ki = 150 nM | [1] | ||
| RB 2 | Drug Info | Ki = 3070 nM | [1] | ||
| References | |||||
| REF 1 | Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold. J Med Chem. 2010 Mar 11;53(5):2076-86. | ||||
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